DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Spata5

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_008759154.1	Gene:	Spata5 / 361935	RGDID:	1310478	Length:	893	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	93/275 - (33%)
Similarity:	154/275 - (56%)	Gaps:	5/275 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 VSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGM 158
            |::..|.||:|.::.:||.:.||::..:|||...: .||:|:||:||||.|||:||:|.|.|.|.
  Rat   350 VTYDMIGGLNSQLKAIREIIELPLKQPELFKSYGI-PAPRGLLLYGPPGTGKTMIARAVANEVGA 413

  Fly   159 RFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFM 223
            ....::...:..|:|||::.....:|:.|:...|.||||||:|:....|.....|....:....:
  Rat   414 YVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQSEVEKRVVASLL 478

  Fly   224 MLWDGL-STNANSTVIVMGATNRPQDLDKAIVR--RMPAQFHIGLPSETQRKDIL-KLILQSEEV 284
            .|.||: |..:...|:|:|||||||.||.|:.|  |...:..||:|:...|.||| ||:.:...:
  Rat   479 TLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDILQKLLRRVPHL 543

  Fly   285 SQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNNVRITMDDLLGSHLK 349
            ....:|.||:...:|:.|:||:.:|..|.:|.:|:::..:.....:.....|:||::|.|.....
  Rat   544 LTKAELLRLANNAHGYVGADLKALCNEAGLYALRRVLRKQPNLPDSKVAGMVKITLNDFLQGMND 608

  Fly   350 IKESKMHTSSLFLEN 364
            |:.|.|...::.:.|
  Rat   609 IRPSAMREVAIDVPN 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	53/136 (39%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	50/132 (38%)
Spata5	XP_008759154.1	CDC48_N	64..132	CDD:304500
		SpoVK	370..882	CDD:223540	86/255 (34%)
		AAA	390..522	CDD:278434	49/131 (37%)
		AAA	664..796	CDD:278434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900