Protein Alignment nmd and Vps4b

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001020887.1
• Gene: Vps4b / 360834
• RGDID: 1305969
• Length: 444
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 111/314 - (35%)
• Similarity: 172/314 - (54%)
• Gaps: 26/314 - (8%)

  Fly    46 KNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSD------YELMIASHLVVPADITVSWADIAGLDS 104
            |.||..|.:.||| ....:::|....|:..||      .:..:...:|:... .|.|:|:|||:.
  Rat    79 KEKKPQKPMKEEQ-SGPVDEKGNDSDGEAESDDPEKKKLQNQLQGAIVIERP-NVKWSDVAGLEG 141

  Fly   105 VIQELRESVVLPIQHKDLFKHSKL-WQAPKGVLLHGPPGCGKTLIAKATAKEA-GMRFINLDVAI 167
            ..:.|:|:|:|||:...||...:. |   :|:||.||||.||:.:|||.|.|| ...|.::..:.
  Rat   142 AKEALKEAVILPIKFPHLFTGKRTPW---RGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSD 203

  Fly   168 LTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTN 232
            |..||.|||:||...:|.||...:|.|||||||||...||:.|:.||...:||:|::...|:..:
  Rat   204 LVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVD 268

  Fly   233 ANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEVS-QDVDLNRLSKL 296
             |..::|:||||.|..||.||.||...:.:|.||....|..:.:|.|.|.:.| .:.|...|.:.
  Rat   269 -NDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRK 332

  Fly   297 TNGFSGSDLREMCRNASVYRMRQLITS------RDPSATALDRNNVRITMDDLL 344
            |:|:||:|:..:.|:|.:..:|::.::      |.||     |.:....::|||
  Rat   333 TDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPS-----RADPNCIVNDLL 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	72/166 (43%)
		AAA_lid_3	287..323	CDD:465537	10/35 (29%)
Vps4b	NP_001020887.1	MIT_VPS4	7..69	CDD:239141
		RecA-like_VPS4	128..298	CDD:410929	74/174 (43%)
		AAA_lid_3	325..366	CDD:465537	10/40 (25%)
		Vps4_C	381..441	CDD:462762	1/1 (100%)