DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and TER94

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	121/351 - (34%)
Similarity:	186/351 - (52%)	Gaps:	37/351 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DNFGLGGSDLSKGQIFQVLVRLSVASLITYYSVKWMMNQMD--PTSKNKKKAKVLAEEQLKRLA- 63
            ::.|..|:||              |||.:..:::.:..:||  ....:|..|:|||.     ||
  Fly   424 ESHGHVGADL--------------ASLCSEAALQQIREKMDLIDLEDDKIDAEVLAS-----LAV 469

  Fly    64 EQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKL 128
            ..|.|:....:.|...|. .:.:.||   ..:|.||.||:||.:||:|.|..|::|.|.|....:
  Fly   470 TMENFRYAMTKSSPSALR-ETVVEVP---NTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGM 530

  Fly   129 WQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPC 193
             |..:|||.:|||||||||:|||.|.|....||::....|...|:|||:.....:|..|....||
  Fly   531 -QPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPC 594

  Fly   194 IIFIDEIDSFLRSR--NMNDHEATA-MMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVR 255
            ::|.||:||..::|  |:.|....| .:..|.:...||:....|  |.::||||||..:|.||:|
  Fly   595 VLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKN--VFIIGATNRPDIIDPAILR 657

  Fly   256 --RMPAQFHIGLPSETQRKDILKLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMR 318
              |:....:|.||.:..|:.|||..|:...::::|||..::|:|.||||:||.|:|:.|....:|
  Fly   658 PGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIR 722

  Fly   319 QLITS--RDPSATALDRNNVRITMDD 342
            |.|.:  |.....|.::|:. :.||:
  Fly   723 QAIEAEIRREKERAENQNSA-MDMDE 747

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	54/138 (39%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	53/134 (40%)
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	121/351 (34%)
		CDC48_N	47..129	CDD:280513
		CDC48_2	153..213	CDD:215011
		AAA	263..392	CDD:278434
		AAA	536..669	CDD:278434	53/134 (40%)
		Vps4_C	<741..783	CDD:286426	2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810