Protein Alignment nmd and Fign

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001099954.1
• Gene: Fign / 295649
• RGDID: 1308174
• Length: 759
• Species: Rattus norvegicus
• Alignment Length: 313
• Identity: 95/313 - (30%)
• Similarity: 161/313 - (51%)
• Gaps: 27/313 - (8%)

  Fly    44 TSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELM-IASHLVVPADITVSWADIAGLDSVIQ 107
            ||.|..     .:||||.              :|..|: :.::.::.....|.|:||||||.|..
  Rat   451 TSSNHS-----VDEQLKN--------------TDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKA 496

  Fly   108 ELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKW 172
            .::|.|:.|:...|.|  |.|...|:.:||.||.|.||||:.:..|.:.|..|..:..:.|..||
  Rat   497 VIKEEVLWPVLRSDAF--SGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKW 559

  Fly   173 YGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTV 237
            .||::|:..|.|.:|...:|.:||:.:||..|.|:...:|...:.|:|:|:|..|.:.|:|...:
  Rat   560 LGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQI 624

  Fly   238 IVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDIL-KLILQSEEVSQDVDLNRLSKLTNGFS 301
            :|:.||::|:::|:::.|....:..|.||..|.|..|: :|:.|......|.:...|.:.|.|||
  Rat   625 VVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFS 689

  Fly   302 GSDLREMCRNASVYRMRQLITSRDPSATALDRNNVR-ITMDDLLGSHLKIKES 353
            |.|:..:|:.|:|..:..:..:   ..:|:..:.:| ||..|...:..||:.|
  Rat   690 GLDVAHLCQEAAVGPLHAMPAT---DLSAIMPSQLRPITYQDFENAFCKIQPS 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	57/164 (35%)
		AAA_lid_3	287..323	CDD:465537	11/35 (31%)
Fign	NP_001099954.1	RecA-like_fidgetin	487..650	CDD:410931	57/164 (35%)
		AAA_lid_3	675..>706	CDD:465537	11/30 (37%)
		Vps4_C	<723..756	CDD:462762	6/17 (35%)