Protein Alignment nmd and vps4

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_593086.1
• Gene: vps4 / 2542054
• PomBaseID: SPAC2G11.06
• Length: 432
• Species: Schizosaccharomyces pombe
• Alignment Length: 363
• Identity: 114/363 - (31%)
• Similarity: 187/363 - (51%)
• Gaps: 65/363 - (17%)

  Fly    46 KNKKKAKVLAEEQLKRLAEQEGFKLRGQE----------------------------FSDYELM- 81
            ||:|..:::..:.::.|...|..|:..||                            .||.:.:
pombe    48 KNEKSKEIIRSKVIEYLDRAEKLKVYLQEKNNQISSKSRVSNGNVEGSNSPTANEALDSDAKKLR 112

  Fly    82 --IASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHS-KLWQAPKGVLLHGPPGC 143
              :.|.::|... .|.|.|||||::..:.|:|:|:|||:...||.|. |.|   .|:||:||||.
pombe   113 SALTSAILVEKP-NVRWDDIAGLENAKEALKETVLLPIKLPQLFSHGRKPW---SGILLYGPPGT 173

  Fly   144 GKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRN 208
            ||:.:|||.|.|||..|.::..:.|..||.|||::|...:|.:|...:|.|||||||||...||:
pombe   174 GKSYLAKAVATEAGSTFFSISSSDLVSKWMGESERLVRQLFEMAREQKPSIIFIDEIDSLCGSRS 238

  Fly   209 MNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKD 273
            ..:.|::..:||:|::..:|:..: .|.|:|:||||.|..||.||.||...:.:|.||:...|..
pombe   239 EGESESSRRIKTEFLVQMNGVGKD-ESGVLVLGATNIPWTLDSAIRRRFEKRIYIPLPNAHARAR 302

  Fly   274 ILKL---ILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSR----------- 324
            :.:|   .:.||..||  |...|:|:|:|:||||:..:.|:|.:..:|::.|:.
pombe   303 MFELNVGKIPSELTSQ--DFKELAKMTDGYSGSDISIVVRDAIMEPVRRIHTATHFKEVYDNKSN 365

  Fly   325 ----------DPSATALDRNNVRITMDDLLGSHLKIKE 352
                      ||.  |.:.:.:.:..:|::...|.:::
pombe   366 RTLVTPCSPGDPD--AFESSWLEVNPEDIMEPKLTVRD 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	73/165 (44%)
		AAA_lid_3	287..323	CDD:465537	12/35 (34%)
vps4	NP_593086.1	cell_div_CdvC	34..430	CDD:468935	114/363 (31%)
		P-loop containing Nucleoside Triphosphate Hydrolases	123..292	CDD:476819	75/173 (43%)