DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Iqca1l

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_808344.3	Gene:	Iqca1l / 231045	MGIID:	3045319	Length:	825	Species:	Mus musculus

Alignment Length:	372	Identity:	81/372 - (21%)
Similarity:	153/372 - (41%)	Gaps:	88/372 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 TSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAG----LDS 104
            :.|.||:..:..:..:..|.|              ||:|...:...|.:|:|  |..|    |.|
Mouse   477 SGKKKKEKDLTPDRSVDSLFE--------------ELVIIGLIKKSALVTLS--DYIGDCLYLGS 525

  Fly   105 VIQ-----------ELRESV----VLPIQHKDLFKHSKLWQAP--KGVLLHGPPGCGKTLIAKAT 152
            .:.           ::|:::    ||.:...|:  |:   .||  :.:||.||.|.||.::.:|.
Mouse   526 TLTLANKMPMPSLFDIRQNMALYGVLRLGSHDI--HT---MAPLVRSILLVGPSGMGKKMLVQAV 585

  Fly   153 AKEAGMRFINLDVAILTDKWYGE--SQKLTSAVFSLASRIEPCIIFIDEID-SFLR-----SRNM 209
            ..|.|....:|....|..|:.|:  :|.|...||.:|..::|.:|:|...: :|.:     .|.|
Mouse   586 CTETGANLFDLSPDNLMGKYPGKNGAQLLVHIVFKVARLLQPSVIWIGNTEKTFYKKVPKEERTM 650

  Fly   210 NDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLD-KAIVRRMPAQFHIGLPSETQRKD 273
            :...    :|...|.....||  ....|:::|.|.|||..: |.:.|.......|..|....|..
Mouse   651 DPKR----IKKDLMRATKQLS--PGDRVMLIGTTERPQLAEMKGLCRFYERILFIPRPDYASRYV 709

  Fly   274 ILKLILQSE----EVSQDVDLNRLSKLTNGFSGSDLREMCRNA-SVYRMRQLI------------ 321
            :.|.:::|:    :::..:|::.|:::::|::.|.:.:..::. :..|:.|||
Mouse   710 LWKRMIESQGRGVQLTSSLDVSALARVSDGYTPSHILQSIQSVLTERRLLQLIKKPLVASEFVGH 774

  Fly   322 -TSRDP-------------SATALDRNNVRITMDDLLGSHLKIKESK 354
             ...||             ..|.|.:.|::.|.|.|.....::.:.|
Mouse   775 LARLDPVYREEEESLKEWFFKTPLGKKNMKFTKDQLEAEEARLTKEK 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	39/144 (27%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	38/138 (28%)
Iqca1l	NP_808344.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..378
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	459..487		3/9 (33%)
		SpoVK	<566..745	CDD:223540	46/184 (25%)
		AAA	568..701	CDD:278434	38/138 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810