DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Pex6

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_663463.1	Gene:	Pex6 / 224824	MGIID:	2385054	Length:	981	Species:	Mus musculus

Alignment Length:	312	Identity:	99/312 - (31%)
Similarity:	161/312 - (51%)	Gaps:	29/312 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LAEQE-------GFKLRGQEFSDY--ELMIASHLVV--PADITVSWADIAGLDSVIQELRESVVL 115
            |:|::       ||.|..::|...  :|..|....|  |...:|||.|:.||..|.:|:.|::.|
Mouse   660 LSEEDEGDLCVAGFPLLAEDFGQALDQLQTAHSQAVGAPRIPSVSWHDVGGLQDVKKEILETIQL 724

  Fly   116 PIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLT 180
            |::|.:|.   .|.....|:|||||||.||||:|||.|.|..:.|:::....|.:.:.|:|::..
Mouse   725 PLEHPELL---SLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENV 786

  Fly   181 SAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAM--MKTQFMMLWDGLSTNANSTVIVMGAT 243
            ..||:.|....|||||.||:||...||..:......|  :.:|.:...|||  ::...|.|:|||
Mouse   787 REVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGL--HSTQDVFVIGAT 849

  Fly   244 NRPQDLDKAIVRRMPAQF----HIGLPSE-TQRKDILKLILQSEEVSQDVDL-NRLSKLTNGFSG 302
            |||..||.|::|  |.:|    .:|...: ..:..:|..|.:..::...|.| |.|.......:|
Mouse   850 NRPDLLDPALLR--PGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLANVLDCCPPQLTG 912

  Fly   303 SDLREMCRNASVYRMRQLITSRD-PSATALDRNNVRITMDDLLGSHLKIKES 353
            :||..:|.:|.:..:::.:  || .....|..:.:.:||:|||.:..:::.|
Mouse   913 ADLYSLCSDAMMTALKRRV--RDLEEGLELRSSALLLTMEDLLQAAARLQPS 962

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	55/139 (40%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	53/135 (39%)
Pex6	NP_663463.1	SpoVK	464..968	CDD:223540	99/312 (32%)
		AAA	467..596	CDD:278434
		AAA	744..872	CDD:278434	51/131 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900