DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and prx-1

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_510386.2	Gene:	prx-1 / 181538	WormBaseID:	WBGene00004191	Length:	996	Species:	Caenorhabditis elegans

Alignment Length:	344	Identity:	97/344 - (28%)
Similarity:	170/344 - (49%)	Gaps:	35/344 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DPTSKNKKKAKVLAEEQLKRLAEQEGFK--LRGQEF-------SDYELMIASHL--VVPADITVS 95
            |..|:..||:......::::||.....:  ::|.::       ..:|..:|..:  :....:..:
Worm   662 DIISEIVKKSDGYTFSEIEKLAVSINVECAIKGVKYITEIEVEKAFECFVAGKMGKIEDGQVLPT 726

  Fly    96 WADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRF 160
            ..|:.|:....:.|.:.::.|.::..||:...: ...||:|||||.||||||:|.||...:....
Worm   727 MEDVGGMFEQKKLLEQVIIWPRKYPQLFESVGV-PVSKGILLHGPSGCGKTLLANATISNSNFSV 790

  Fly   161 INLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMML 225
            :|:....|..|:.|.|::....||..|....|||:|.||:||....|..:....|..:..|.:..
Worm   791 VNVKGPELLSKYIGASEENVRLVFEKARSCAPCILFFDELDSLAPKRGHDSTGVTDRVVNQLLTE 855

  Fly   226 WDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQF--HI--GLPSETQRKDILKLILQSEEVSQ 286
            .|| :......||::|.|:|...:|.|::|  |.:|  |:  |.|.:|:|.||:| :|.::....
Worm   856 LDG-AEGGMKGVIILGCTSRIDLIDDALLR--PGRFDHHVYCGHPEKTERLDIMK-VLTNKLKPT 916

  Fly   287 DVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNNVRI---TMDDLLGSHL 348
            |||...|::.|:|:||:||:.:..||..|..||:....|    .|:.:||.|   :::.:....:
Worm   917 DVDFECLAQKTDGWSGADLQLLFTNAQFYNARQIAKEED----GLEEDNVPIDQASIESVFNDSI 977

  Fly   349 -KIKESKMHTSSLFLENRI 366
             |.|.|:       ::|||
Worm   978 PKPKRSQ-------VDNRI 989

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	49/137 (36%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	46/133 (35%)
prx-1	NP_510386.2	PEX-1N	103..179	CDD:370392
		P-loop_NTPase	481..>522	CDD:393306
		SpoVK	511..938	CDD:223540	81/280 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000