Protein Alignment nmd and pch-2

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_495711.1
• Gene: pch-2 / 174313
• WormBaseID: WBGene00008641
• Length: 424
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 84/399 - (21%)
• Similarity: 157/399 - (39%)
• Gaps: 103/399 - (25%)

  Fly     6 LGGSDLSKGQIFQVLVRLSV-ASLITYYSVKWMMNQMDPTSKNKKKAKVLAEEQLKRLAEQEGFK 69
            :|..:|..|::|:.:..|:: .|.|..|.    :::..|.|:|              :.:.:|
 Worm    71 IGTCELRDGELFENVNDLTINPSNIHVYK----LHKDGPLSQN--------------IGDDDG-- 115

  Fly    70 LRGQEFSDYELMIASHL-VVP-ADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAP 132
                    .|.:|.|.| .:| .:....|.::....::..|:...|....:..:...::|:....
 Worm   116 --------DESIIGSQLWQLPCVEFDSIWENLIYDSNLKNEVMSYVAALARLSEKHVNTKIINVN 172

  Fly   133 KGVLLHGPPGCGKTLIAKATAKEAGMR---------FINLDVAILTDKWYGESQKLTSAVFSLAS 188
            :.:||.||||.|||.:.|..|:...:|         .:.::...|..||:.||.||...:|....
 Worm   173 RLILLTGPPGTGKTSLCKGLAQHLSIRMNDKYSKSVMLEINSHSLFSKWFSESGKLVQKMFDQID 237

  Fly   189 RI---EPCIIF--IDEIDSF--------LRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVM 240
            .:   |.|::|  |||::|.        .||...:...|...:.||.    |.:....|  |:::
 Worm   238 ELAEDEKCMVFVLIDEVESLGMCRESSSSRSEPSDAIRAVNALLTQI----DRIRRRDN--VLIL 296

  Fly   241 GATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILK-LILQSEEVSQDVD--------------- 289
            ..:|....||||:|.|.....::|.||:..|..:|| .|::...:...:|
 Worm   297 CTSNLESTLDKALVDRADIVKNVGQPSDFARYSMLKSSIMELARIGVVIDNEVHTDYWPQDICDT 361

  Fly   290 ----------LNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNNVRITMDDLL 344
                      |.::::...|.||         .::..:..|:.|:.|..|        ||:.:.:
 Worm   362 KAPRNEFTEILFKIAQEARGLSG---------RAISMLPTLVYSKSPEET--------ITLPNCM 409

  Fly   345 GSHLK-IKE 352
            ...|: :||
 Worm   410 NLFLEAVKE 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	45/186 (24%)
		AAA_lid_3	287..323	CDD:465537	6/60 (10%)
pch-2	NP_495711.1	McrB	13..>204	CDD:441011	33/160 (21%)
		RecA-like_Pch2-like	121..319	CDD:410916	49/203 (24%)