Protein Alignment nmd and mei-1

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001370150.1
• Gene: mei-1 / 172612
• WormBaseID: WBGene00003183
• Length: 475
• Species: Caenorhabditis elegans
• Alignment Length: 230
• Identity: 86/230 - (37%)
• Similarity: 134/230 - (58%)
• Gaps: 6/230 - (2%)

  Fly    93 TVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKL-WQAPKGVLLHGPPGCGKTLIAKATAKEA 156
            |:|..||.|:..|.|.|.|:|.||:...:.|:..:. |   |.::|.||||.||||||:|.|.|:
 Worm   189 TMSLDDIIGMHDVKQVLHEAVTLPLLVPEFFQGLRSPW---KAMVLAGPPGTGKTLIARAIASES 250

  Fly   157 GMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSR-NMNDHEATAMMKT 220
            ...|..:....|:.||.|:|:|:...:|.||....|.||||||||:....| |..:|||:..:|:
 Worm   251 SSTFFTVSSTDLSSKWRGDSEKIVRLLFELARFYAPSIIFIDEIDTLGGQRGNSGEHEASRRVKS 315

  Fly   221 QFMMLWDGLSTNANS-TVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEV 284
            :|::..||.....:| .|.|:.|||.|.:||:|:.||...:..|.||....||.:::..::....
 Worm   316 EFLVQMDGSQNKFDSRRVFVLAATNIPWELDEALRRRFEKRIFIPLPDIDARKKLIEKSMEGTPK 380

  Fly   285 SQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQ 319
            |.:::.:.|:..|.||||:|:..:||.|::..:|:
 Worm   381 SDEINYDDLAARTEGFSGADVVSLCRTAAINVLRR 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	67/167 (40%)
		AAA_lid_3	287..323	CDD:465537	11/33 (33%)
mei-1	NP_001370150.1	SpoVK	53..414	CDD:440232	85/227 (37%)
		RecA-like_VPS4-like	195..359	CDD:410917	66/166 (40%)