Protein Alignment cas and casz1

DIOPT Version :10

• Sequence 1: NP_524677.1
• Gene: cas / 44018
• FlyBaseID: FBgn0004878
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_009295241.1
• Gene: casz1 / 559053
• ZFINID: ZDB-GENE-060130-108
• Length: 2022
• Species: Danio rerio
• Alignment Length: 850
• Identity: 215/850 - (25%)
• Similarity: 332/850 - (39%)
• Gaps: 232/850 - (27%)

  Fly    12 YMMNLMKQ--------QQQMQLQLPQQQQQQQLAGYTYTQNEDISSSTSVQQQQQQQQEQLQQPQ 68
            |..|.|.:        .||::.:|.::...::|...|       |..:|:..::..::.:..:.:
Zfish   234 YAANTMNEFLNMFGYDDQQVRDELAKKISFEKLKAAT-------SDPSSLSSEEATRRARFSKYE 291

  Fly    69 PDLRKTRTHKR----ISSQNTNCSSSRSCSPNSNLIAFQP--------QQYPGATAATPSTPNSH 121
            ..:||.:..:.    :.::....:|..:.:|..:....||        |.:|.......|:.|..
Zfish   292 EYIRKLKAGETLPWPVHTKPEVLNSKMTLTPEKSAALIQPTLTAGSEGQIFPPGMDHKQSSLNPA 356

  Fly   122 PSNLVNQMLLQSLPPLTQLMLQQQQQQHLLTTSN------------------LLLTP-------- 160
            |:|..:...|.|........:|:.:....|...|                  .|..|
Zfish   357 PTNQSHIQNLASRASKYDYFIQKLKMGESLREQNGNSYKRPSKYDLENVKFLHLFKPGEGNPDMG 421

  Fly   161 ---------THTPSSL----------GKQDPLQHPLLLGQFAGSEQMATNNFLQSSTVTSTPIER 206
                     ...||..          ||.||   |:|                 ||.:.:|
Zfish   422 GAIAFKTGKVGRPSKYDIRNIQKLIPGKVDP---PVL-----------------SSVLPAT---- 462

  Fly   207 EKAATPAP---SAGATAGNLSAAQVKFEQESADDDEDDDKPLSSLTSCSSSGHTNASSEKLLLSG 268
              |.||.|   :..|.||.:....:..:||                     ||...:::.:..|
Zfish   463 --AGTPGPPVINTAAPAGVVGPPGLPMDQE---------------------GHLGFNTDFMKSS- 503

  Fly   269 VHPLESTTDSLDSPSMYTPVKQPADSSYGLITPVDSDLTPNTPLQPTQTISLLTPPSSEQSKSLV 333
                .|.|||:.:               |.::.|.:.|.|..|  .|:.:::..
Zfish   504 ----FSKTDSITT---------------GTVSSVKNGLPPEKP--ATEDVNVYQ----------- 536

  Fly   334 SLSAASGLDALLQNEEVLKNLRKVSSYLECENSLCRQENLREHFHCHEEPCQGKILSKKDDIIRH 398
                              |.:.:.|....|.:..|..: .|||:||.:..|..:..:.|.|:|||
Zfish   537 ------------------KYIARFSGSQHCGHVHCAYQ-YREHYHCMDPECNYQRFTSKQDVIRH 582

  Fly   399 LKWHKKRKESLKLGFARFSSSDDCAPAYGEGCAYNWKQTHYHCVYEHCPKVYVSTSDVQMHANFH 463
            ...||||..||:.||.|||..|||: .|..||..|.|.|||||:...|.|||.|||||..|.|||
Zfish   583 YNMHKKRDNSLQHGFMRFSPLDDCS-VYYHGCHLNGKSTHYHCMQVACNKVYTSTSDVMTHENFH 646

  Fly   464 RKDSEIVNEGFRRFRAHETCRIEDCPFFGKKISHYHCCREGCTHTFKNKADMDKHKTYHLKDHQL 528
            :|:::::|:||:||||.|.|....|.|:.:|.:|:||.|.|||.|||||.|::|||:||:||...
Zfish   647 KKNAQLINDGFQRFRAVEDCGTVGCQFYAQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAY 711

  Fly   529 KMDGFKKILKTEVCPFDACKFSTVCNHIHCVREGCDYILHSSSQMISHKRKHDRQDGEQAYQQFK 593
            ..|||||..|.|.|.::.|.:|...||.||:|:||.:...|:|||.||||||:|       :..:
Zfish   712 AKDGFKKFYKYEECKYEGCVYSKATNHFHCIRQGCGFTFTSTSQMTSHKRKHER-------RHIR 769

  Fly   594 IKQDVEESSLDAMPQQQQQQQQQQPTSLSQSQSSSSVCGGSNTSTPLSSLSAEHFLARKRGRPPK 658
            ....:..:|...:|:::|.:           .|:..:...|..|:..|||||.
Zfish   770 SSGVLGLTSSFLLPKEEQDE-----------SSNDDLMDYSAISSKNSSLSAS------------ 811

  Fly   659 KIQLPADAQQSEAKRL-------KVEDESSNPAMLLPQSQPAAAVHPLTSGLFPGLLP------- 709
                |...|.|....|       ....:|..|...||   ||:.:..|.|...|..:|
Zfish   812 ----PTTQQSSTIPHLLPTPTTTMCSSQSVKPTAALP---PASRISTLLSQALPSNVPMALALSN 869

  Fly   710 ---AAAAPGVDPTAPNFQL---THLMALFQLQNPLFYQNLYPGMTQNSSMLGNLAALSAASAAAA 768
               |.|:....|..|...:   .....|......:.:......:.|.|:..|:|||.:.||...:
Zfish   870 SALAGASNAFFPLIPRMPMPLPPSAAGLISAATSVAHSMPSDSLPQTSTPTGDLAAATVASTPTS 934

  Fly   769 AAAAA 773
            .||::
Zfish   935 FAASS 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cas	NP_524677.1	None
casz1	XP_009295241.1	DUF5585	<813..>1025	CDD:465521	28/129 (22%)