Protein Alignment cas and Casz1

DIOPT Version :9

• Sequence 1: NP_524677.1
• Gene: cas / 44018
• FlyBaseID: FBgn0004878
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_008762539.1
• Gene: Casz1 / 313713
• RGDID: 1563533
• Length: 1889
• Species: Rattus norvegicus
• Alignment Length: 766
• Identity: 231/766 - (30%)
• Similarity: 323/766 - (42%)
• Gaps: 165/766 - (21%)

  Fly    83 QNTNCSSSRSCSPNSNLIAFQPQQYPGATAATPSTPNSHPSNLVNQMLLQSLPPLTQLMLQQQQQ 147
            |||....:|.       |:|: :.:.|:|          |..:.:.||..|...|::.....:.:
  Rat   216 QNTRDELARK-------ISFE-KLHAGST----------PEVVASSMLPSSEDTLSKRARFSKYE 262

  Fly   148 QHL--LTTSNLLLTPTHTPSSLGKQDPLQHPLLLGQFAGSEQMATNNFLQSSTVTSTPIEREKAA 210
            :::  |.....|..|.|...:..:             ||.|.:..   |.|..:.|.....|..|
  Rat   263 EYIRKLKAGEQLPWPAHGSKAEDR-------------AGKEVVGP---LPSLRLPSNTAHLETKA 311

  Fly   211 T--PAPS-AGATAGNLSAAQVKFEQESADDDEDDDKPLSSLTSCSS----SGHTNASSEKLLLSG 268
            |  |.|| :.....||.|...|:           |..:..|.:..|    :|.|.....|..|..
  Rat   312 TILPLPSHSSVQMQNLVARASKY-----------DFFIHKLKTGESLRPQNGSTYKKPSKYDLEN 365

  Fly   269 VHPLESTTDSLDSPSM-----YTPVKQPADSSY---GLITPVDSDLTPNTPLQPTQTISLLTPPS 325
            |..|........||.|     :...|....|.|   |:..|..:.:.|...|.||...::.:.||
  Rat   366 VKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGTTKIPPAPSLVPTPLTNVPSAPS 430

  Fly   326 S----------------EQSKSLVSL--SAASGLDALLQN----------EEV---LKNLRKVSS 359
            :                |..||..|.  |..:|..:.::|          |:|   .|.:.:.|.
  Rat   431 APGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSG 495

  Fly   360 YLECENSLCRQENLREHFHCHEEPCQGKILSKKDDIIRHLKWHKKRKESLKLGFARFSSSDDCAP 424
            ...|.:..|..: .|||:||.:..|..:..:.|.|:|||...||||..||:.||.|||..|||:
  Rat   496 SQHCGHIHCAYQ-YREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCS- 558

  Fly   425 AYGEGCAYNWKQTHYHCVYEHCPKVYVSTSDVQMHANFHRKDSEIVNEGFRRFRAHETCRIEDCP 489
            .|..||..|.|.|||||:...|.|||.|||||..|.|||:|:::::|:||:||||.|.|...||.
  Rat   559 VYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQ 623

  Fly   490 FFGKKISHYHCCREGCTHTFKNKADMDKHKTYHLKDHQLKMDGFKKILKTEVCPFDACKFSTVCN 554
            |:|:|.:|:||.|.|||.|||||.|::|||:||:||.....|||||..|.|.|.::.|.:|...|
  Rat   624 FYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATN 688

  Fly   555 HIHCVREGCDYILHSSSQMISHKRKHDRQD-------GEQAYQQFKIKQDVEESSLDAMPQQQQQ 612
            |.||:|.||.:...|:|||.||||||:|:.       |..|........:.||||.|.:...
  Rat   689 HFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPASLLGTKDTEHEESSNDDLVDF--- 750

  Fly   613 QQQQQPTSLSQSQSSSSVCGGSNTSTPLSSLSAEHFLARKRGRPPKKIQLPADAQQSEAKRLKVE 677
                  ::||...||.|....|..|:  :||:|                 .|.|..:||.....:
  Rat   751 ------SALSSKNSSLSASPNSQQSS--ASLAA-----------------AAAATTAEAVPSAAK 790

  Fly   678 DESSNPAMLLPQSQPAAAVHPLTSGLFPGLLPAAAAPGVDPTAPNFQLTHLMALFQLQNPLFYQN 742
            ..:|..|.||||.         .||..| |..|.:..|:..|.|.|.
  Rat   791 PPNSKMAGLLPQG---------LSGSIP-LALALSNSGLPTTTPYFP------------------ 827

  Fly   743 LYPGMTQNSSMLGNLAALSAASAAAAAAAA-------ANGAGVQQPKAEFS 786
            |.||....|..:|:...|.:.::.|..:|.       |:|||...|.|..|
  Rat   828 LLPGRGSASLPVGSPGLLGSMTSGATTSATPDMPALMASGAGDSAPTAATS 878

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336630
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4377
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006505
OrthoInspector	1	1.000	-	-		oto96365
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12451
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.890