Protein Alignment sol and Capn12

DIOPT Version :10

• Sequence 1: NP_476738.3
• Gene: sol / 44014
• FlyBaseID: FBgn0003464
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: NP_001104277.1
• Gene: Capn12 / 60594
• MGIID: 1891369
• Length: 720
• Species: Mus musculus
• Alignment Length: 468
• Identity: 139/468 - (29%)
• Similarity: 203/468 - (43%)
• Gaps: 99/468 - (21%)

  Fly   998 LTKWQN---IIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGEGNPVVQWRRPHEINCDGGAYPP 1059
            |.|.||   |.:.|.|:..||.|..||..|.:|.|:......|....|:|:||||...:     |
Mouse    26 LFKGQNYEAIRRACLDSGILFRDPCFPAGPDALGYDKLGPDSEKAKGVEWKRPHEFCAE-----P 85

  Fly  1060 WAVFRTPLPSDICQGVLGNCWLLSALAVLAEREDLVKEVLVTKEICGQ-------GAYQVRLCKD 1117
            ..:......:|:|||.|||||||:|.|.|.....|:..|:..    ||       |.:..:|.:.
Mouse    86 QFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPP----GQGFQDGYAGVFHFQLWQF 146

  Fly  1118 GKWTTVLVDDLLPCDKRGHLVYSQA-KRKQLWVPLIEKAVAKIHGCYEALVSGRAIEGLATLTGA 1181
            |:|..|:|||.||. :.|.|::.:: :|.:.|.||:|||.||:||.||.:..|...|.....||.
Mouse   147 GRWVDVVVDDKLPV-REGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGG 210

  Fly  1182 PCESIPLQASSLPMPSEDELDKDLIWAQLLSSRCVRFLMGASC--GGGNMKVDEEEYQQKGLRPR 1244
            ..|.:.|:.::   |.        ::|.|..:.....|:||:.  ..|.::.||      ||...
Mouse   211 VGEVLYLRQNT---PG--------VFAALRHALAKESLVGATALSDRGEIRTDE------GLVKG 258

  Fly  1245 HAYSVLDVKDIQ-GH---RLLKLRNPWGHYSWRGDWSDDSSLW---TDDLRDALMPHGASEGVFW 1302
            |||||.....:. |.   |||:||||||...|.|.|||....|   ..:.||||:.. ..:|.||
Mouse   259 HAYSVTGTHKMSLGFTKVRLLRLRNPWGRVEWSGPWSDSCPRWDMLPSEWRDALLVK-KEDGEFW 322

  Fly  1303 ISFEDVLNYFDCIDICKVR----------SGWNEVRLQG-------------TLQPLCSISCVLL 1344
            :..:|.|.:|:.:.||.:.          .||:....||             :.:...:.....|
Mouse   323 MELQDFLTHFNTVQICSLSPEVLGPSPAGGGWHIHIFQGRWVRGFNSGGSQPSAENFWTNPQFRL 387

  Fly  1345 TVLEPTEAEFTLFQE---------GQRNSEKSQRSQLDLCVVIFRTRSPAAPEIGRLVEHSKRQV 1400
            |:|||.|.|....:|         |.|...:..|  :..|.|:.           .|::.::|.:
Mouse   388 TLLEPDEEEDDDDEEGPWGGWGAAGARGPARGGR--VPKCTVLL-----------SLIQRNRRCL 439

  Fly  1401 RG------FVGCH 1407
            |.      .||.|
Mouse   440 RAKGLTYLTVGFH 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sol	NP_476738.3	zf-RanBP	6..34	CDD:395516
		RanBP2-type Zn finger	10..29	CDD:275376
		zf-RanBP	135..164	CDD:395516
		zf-RanBP	643..672	CDD:395516
		RanBP2-type Zn finger	647..667	CDD:275375
		zf-RanBP	704..731	CDD:395516
		RanBP2-type Zn finger	708..727	CDD:275376
		zf-RanBP	747..774	CDD:395516
		RanBP2-type Zn finger	749..768	CDD:275376
		zf-RanBP	927..954	CDD:395516
		CysPc	1001..1328	CDD:128526	116/356 (33%)
Capn12	NP_001104277.1	Peptidase_C2	46..339	CDD:459889	107/320 (33%)
		Domain III	342..541		23/124 (19%)
		Calpain_III	352..531	CDD:238132	23/114 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..415		4/21 (19%)
		Domain IV	542..720
		EFh_PEF	568..720	CDD:355382
		EF-hand motif	597..624	CDD:320054
		EF-hand motif	625..654	CDD:320054
		EF-hand motif	661..689	CDD:320054
		EF-hand motif	691..719	CDD:320054