DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sol and capn2b

DIOPT Version :9

Sequence 1:	NP_476738.3	Gene:	sol / 44014	FlyBaseID:	FBgn0003464	Length:	1594	Species:	Drosophila melanogaster
Sequence 2:	NP_001018177.1	Gene:	capn2b / 563053	ZFINID:	ZDB-GENE-050522-84	Length:	696	Species:	Danio rerio

Alignment Length:	343	Identity:	115/343 - (33%)
Similarity:	167/343 - (48%)	Gaps:	51/343 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   999 TKWQN-----IIQYCRDNSELFVDDSFPPAPKSLYY---NPASGAGEGNPVVQWRRPHEINCD-- 1053
            ||:.|     :...||....||.|.:||.||:||.:   .|.|....|   :.|:||.|: |.
Zfish    25 TKYLNQDFEALRSECRARGTLFSDPTFPAAPESLGFKELGPNSSKTRG---LVWKRPGEL-CQKP 85

  Fly  1054 ----GGAYPPWAVFRTPLPSDICQGVLGNCWLLSALAVLAEREDLVKEVLVT-KEICG--QGAYQ 1111
                |||          ..:|||||.||:||||:|:|.|.:.||::..|:.. :|..|  .|.:.
Zfish    86 RFIVGGA----------TKTDICQGALGDCWLLAAIASLTQNEDVLARVVPNGQEFDGTYAGIFH 140

  Fly  1112 VRLCKDGKWTTVLVDDLLPCDKRGHL--VYSQAKRKQLWVPLIEKAVAKIHGCYEALVSGRAIEG 1174
            .:..:.|:|..|::||.||. |.|.|  ||| |::.:.|..|:|||.||::||||||..|...||
Zfish   141 FQFWQFGEWVDVVIDDRLPV-KDGELLFVYS-AEKNEFWSALLEKAYAKVNGCYEALSGGSTSEG 203

  Fly  1175 LATLTGAPCESIPLQASSLPMPSEDELDKDLIWAQLLSSRCVRFLMGASCGGGNMKVDEEEYQQK 1239
            ....||...||..::.:  |......:.|.|....||.  |...:..|:        |.|...::
Zfish   204 FEDFTGGIAESYEIRKA--PTNLFQIIQKALEAGALLG--CSIDITSAA--------DSEAITRQ 256

  Fly  1240 GLRPRHAYSVLDVKDI----QGHRLLKLRNPWGHYSWRGDWSDDSSLWTDDLRDALMPHGASEGV 1300
            .|...||||:....::    :..:|:::|||||...|.|.|||:|..|............|.:|.
Zfish   257 KLVKGHAYSLTGATEVNYRGRKEKLVRMRNPWGQVEWTGAWSDNSPEWNSVAASERPDASAEDGE 321

  Fly  1301 FWISFEDVLNYFDCIDIC 1318
            ||::|.:.|..:..|:||
Zfish   322 FWMAFSEFLTNYSRIEIC 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sol	NP_476738.3	zf-RanBP	6..34	CDD:279035
		RanBP2-type Zn finger	10..29	CDD:275376
		zf-RanBP	135..164	CDD:279035
		zf-RanBP	643..672	CDD:279035
		RanBP2-type Zn finger	647..667	CDD:275375
		zf-RanBP	704..731	CDD:279035
		RanBP2-type Zn finger	708..727	CDD:275376
		zf-RanBP	747..774	CDD:279035
		RanBP2-type Zn finger	749..768	CDD:275376
		zf-RanBP	927..954	CDD:279035
		RanBP2-type Zn finger	931..950	CDD:275376
		CysPc	1001..1328	CDD:128526	113/341 (33%)
capn2b	NP_001018177.1	Peptidase_C2	46..339	CDD:279042	107/320 (33%)
		Calpain_III	354..503	CDD:279416
		EFh	573..628	CDD:238008
		FRQ1	601..>686	CDD:227455
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820