DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sol and Capn13

DIOPT Version :9

Sequence 1:	NP_476738.3	Gene:	sol / 44014	FlyBaseID:	FBgn0003464	Length:	1594	Species:	Drosophila melanogaster
Sequence 2:	NP_001028616.1	Gene:	Capn13 / 381122	MGIID:	2685789	Length:	665	Species:	Mus musculus

Alignment Length:	365	Identity:	105/365 - (28%)
Similarity:	164/365 - (44%)	Gaps:	58/365 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   997 ALTKWQN-----IIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGE----GNPV--VQWRRPHEI 1050
            ::.|::|     :..:|....:||:||:||.|        ||..||    |..:  ::|:||  .
Mouse     8 SVVKFKNQDFRTLRDHCLSRGQLFIDDTFPAA--------ASSIGEKLLRGKHLSKLEWKRP--T 62

  Fly  1051 NCDGGAYPPWAVFRTPLPSDICQGVLGNCWLLSALAVLAEREDLVKEVLVTKEICGQ--GAYQVR 1113
            :.|...|||..:.......||.||:.|:||.|:||..|.:....::::|:.:....|  |.:|.|
Mouse    63 SKDLPFYPPHFILEGASRFDIHQGIAGDCWFLAALGSLTQNPQCLQKILMDQSYSHQYAGIFQFR 127

  Fly  1114 LCKDGKWTTVLVDDLLPCDKRGHL-VYSQAKRKQLWVPLIEKAVAKIHGCYEALVSGRAIEGLAT 1177
            ..:.|:|..|::||.||......| |:.:...|:.|..|:|||.||:.|.|..|..|...:.|..
Mouse   128 FWQCGQWVEVVIDDQLPVIGDNFLFVHPRGGNKEFWPCLMEKAYAKLLGSYSQLHYGYLPDALVD 192

  Fly  1178 LTGAPCESIPLQASSLPMPSEDELDKDLIWAQLLSSRCVRFLMGA--SCGGGNMKVDEEEYQQKG 1240
            |||.....|.|.:|..               .||::.......|:  :|...|...:|.:..:.|
Mouse   193 LTGGVVTIINLHSSPF---------------DLLTTVKTAIQAGSMVACATENGLTEEAKVMENG 242

  Fly  1241 LRPRHAYSVLDVKDIQ----GHRLLKLRNPWGHYSWRGDWSDDSSLW--TDDLRDALMPHGASEG 1299
            |..:|||:|...:.||    ...:::|.||||...|:|.|.|.|..|  |.|.|.:.:.....:|
Mouse   243 LVSQHAYTVTGAEKIQYQGRWEDIIRLWNPWGKTEWKGRWKDGSKEWRETHDPRKSQLYENKEDG 307

  Fly  1300 VFWISFEDVLNYFDCIDICK-----------VRSGWNEVR 1328
            .||:|.:|....|.|:.||.           ....|.::|
Mouse   308 EFWMSCQDFQENFSCLFICNQIPITMDHGVTPNESWRQMR 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sol	NP_476738.3	zf-RanBP	6..34	CDD:279035
		RanBP2-type Zn finger	10..29	CDD:275376
		zf-RanBP	135..164	CDD:279035
		zf-RanBP	643..672	CDD:279035
		RanBP2-type Zn finger	647..667	CDD:275375
		zf-RanBP	704..731	CDD:279035
		RanBP2-type Zn finger	708..727	CDD:275376
		zf-RanBP	747..774	CDD:279035
		RanBP2-type Zn finger	749..768	CDD:275376
		zf-RanBP	927..954	CDD:279035
		RanBP2-type Zn finger	931..950	CDD:275376
		CysPc	1001..1328	CDD:128526	103/359 (29%)
Capn13	NP_001028616.1	Peptidase_C2	31..327	CDD:279042	98/320 (31%)
Capn13	NP_001028616.1	Calpain_III	343..469	CDD:294111	2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820