Protein Alignment sol and Capn11

DIOPT Version :10

• Sequence 1: NP_476738.3
• Gene: sol / 44014
• FlyBaseID: FBgn0003464
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: XP_011244781.1
• Gene: Capn11 / 268958
• MGIID: 1352490
• Length: 753
• Species: Mus musculus
• Alignment Length: 723
• Identity: 175/723 - (24%)
• Similarity: 284/723 - (39%)
• Gaps: 201/723 - (27%)

  Fly   938 YDNCAASVV----------C---------DICSSPRGLASAVLGEALGRKSVRVALTPADIRQES 983
            ||:....||          |         ||..:.:|:.:.:....|..|.|.......:.:.::
Mouse    16 YDSTKVQVVELMGLLALSACEEFLTGAWMDISWAEKGMVATINHSRLKDKGVGQHQNAYNYKNQN 80

  Fly   984 KLMENLRQLEETEALTKWQNIIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGEGNPVVQWRRPH 1048
              .|:||    .|.|.|           .|||.|..||..|:|:.........|....:.|:||.
Mouse    81 --YEDLR----AECLRK-----------GELFEDPFFPAEPRSIGVKNLGPNSEHMQNIYWQRPK 128

  Fly  1049 EINCDGGAYPPWAVFRTPLPSDICQGVLGNCWLLSALAVLAEREDLVKEVLVTKEICGQ---GAY 1110
            :|     .:.|..:.....|:|||||:||:||||:|:..|.....|:..|:...:...:   |.:
Mouse   129 DI-----IHNPQFITNDFSPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRNQSFKKNYAGIF 188

  Fly  1111 QVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQ-LWVPLIEKAVAKIHGCYEALVSGRAIEG 1174
            ..:|.:.|.|..|:|||.|| .:...||:..|..:| .|..|:|||.||:.|.|.||..|..:||
Mouse   189 HFQLWQFGHWLNVVVDDRLP-TRNNKLVFVHASHRQDFWSALLEKAYAKLIGSYGALSGGSTLEG 252

  Fly  1175 LATLTGAPCESIPLQASSLPMPSEDELDKDLIWAQLLSSRCVR-FLMGASCG-GGNMKVDEEEYQ 1237
            |...||...:.||||     .|..:.|       :||.....: .|||.|.. ..|.:|:...:.
Mouse   253 LEDFTGGVAQCIPLQ-----KPPGNML-------RLLKKALEKSSLMGCSIEVTDNSEVETMTHN 305

  Fly  1238 QKGLRPRHAYSVLDVKDI----QGHRLLKLRNPWGHYSWRGDWSDDSSLWTD---DLRDALMPHG 1295
            .  |...|||:|..::|:    :...|::::||||...|.|.|||.::.|.:   |:|..|: |.
Mouse   306 M--LVRGHAYAVTGLEDVYYRDKLETLIRIQNPWGRVEWNGAWSDKATEWEEVSPDVRVQLL-HK 367

  Fly  1296 ASEGVFWISFEDVLNYFDCIDICKV----------RSGWNEVRLQGTLQ---------------- 1334
            ..:|.||:|:||.::.|..::||.:          :|.|:....:|:.:
Mouse   368 KDDGDFWMSYEDFMSNFTLLEICNLTPDALNTWDYKSRWHSTFYEGSWRRGSTAGGCRNHPETFW 432

  Fly  1335 --PLCSISCVLLTVLEPTEAEFTLFQEGQRNSEKSQRSQLDLCVVIFRTRS-------PAAPEIG 1390
              |...||  |..|.:|.:           :|||::  .:..|:|....::       |....||
Mouse   433 SNPQFKIS--LPEVDDPED-----------DSEKNE--MVCTCLVALMQKNWRHAREGPQLLTIG 482

  Fly  1391 RLV------------EHSKRQV------RGF---------VGCHKMLERDIYLLVCLAFNHWHTG 1428
            .::            .|.|:..      .||         |..|..|....|:::...:
Mouse   483 FVIFSVPKEFQNLRDIHLKKDFFLKYRDHGFSEIFINSREVNSHLRLPPGEYVIIPSTY------ 541

  Fly  1429 IEDPHQYPQCILAIHSSKR---LLVEQISPSPHLLADAII-------SLTLTKGQRHEGRE---- 1479
              :||:....:|.:.:.|.   .|::..:...||..:.:.       ||.|.|...:|..|
Mouse   542 --EPHKDADFLLRVFTEKHSETWLLDDANRFEHLQEETVTDKDLDKDSLQLFKIMANEDGEVDMY 604

  Fly  1480 -------GMTA---YYLTKGWA-----GLVVMVE-------NRHE--------NKWIHV--KCDC 1512
                   .|||   .:.|||::     .::.:::       ..||        .||..:  :||.
Mouse   605 ALHKLLNRMTAKLRNFKTKGFSLEVCRRMINLLDKDGSGKLELHEFQVLWKKIKKWTEIFKECDE 669

  Fly  1513 QESYNVVS 1520
            ..|.|:.|
Mouse   670 DRSGNLNS 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sol	NP_476738.3	zf-RanBP	6..34	CDD:395516
		RanBP2-type Zn finger	10..29	CDD:275376
		zf-RanBP	135..164	CDD:395516
		zf-RanBP	643..672	CDD:395516
		RanBP2-type Zn finger	647..667	CDD:275375
		zf-RanBP	704..731	CDD:395516
		RanBP2-type Zn finger	708..727	CDD:275376
		zf-RanBP	747..774	CDD:395516
		RanBP2-type Zn finger	749..768	CDD:275376
		zf-RanBP	927..954	CDD:395516	7/34 (21%)
		CysPc	1001..1328	CDD:128526	107/349 (31%)
Capn11	XP_011244781.1	Peptidase_C2	95..391	CDD:459889	102/316 (32%)
		Calpain_III	405..564	CDD:238132	28/181 (15%)
		EFh_PEF_CAPN11	586..753	CDD:320068	21/92 (23%)
		EF-hand motif	586..614	CDD:320068	6/27 (22%)
		EF-hand motif	629..658	CDD:320068	2/28 (7%)
		EF-hand motif	659..689	CDD:320068	7/19 (37%)
		EF-hand motif	695..722	CDD:320068
		EF-hand motif	723..753	CDD:320068