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Protein Alignment sol and Capn3

DIOPT Version :9

Sequence 1:	NP_476738.3	Gene:	sol / 44014	FlyBaseID:	FBgn0003464	Length:	1594	Species:	Drosophila melanogaster
Sequence 2:	NP_031627.2	Gene:	Capn3 / 12335	MGIID:	107437	Length:	821	Species:	Mus musculus

Alignment Length:	712	Identity:	172/712 - (24%)
Similarity:	276/712 - (38%)	Gaps:	204/712 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   953 PRGLASAVLGE---ALGRKSVRVALTPADIRQESKLMENLRQLEETEALTKWQNIIQYCRDNSEL 1014
            |.|:.||::..   .:|.|              .|..|.||               :.|.:...|
Mouse    39 PSGIYSAIISRNFPIIGVK--------------EKTFEQLR---------------RKCLEKKVL 74

  Fly  1015 FVDDSFPPAPKSLYYNPASGAGEGNPV-VQWRRPHEINCDGGAYPPWAVFRTPLPSDICQGVLGN 1078
            ::|..|||...||:|:      :..|: ..|:||.|| |:...:......||    |||||.||:
Mouse    75 YLDPEFPPDETSLFYS------QKFPIQFVWKRPPEI-CENPRFIIGGANRT----DICQGDLGD 128

  Fly  1079 CWLLSALAVLAEREDLVKEVLVTKEICGQ---GAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYS 1140
            ||.|:|:|.|...|.|:..|:...:...:   |.:..:..:.|.|..|::||.|| .....||::
Mouse   129 CWFLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLP-TYNNQLVFT 192

  Fly  1141 QAK-RKQLWVPLIEKAVAKIHGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPMPSEDELDKD 1204
            ::. |.:.|..|:|||.||:||.||||..|...|.:...||...|...::  ..|......:.|.
Mouse   193 KSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIK--DAPSDMYKIMRKA 255

  Fly  1205 LIWAQLLSSRC-----VRFLMGASCGGGNM---------KVDEEEYQQKGLRPR----------- 1244
            :....|:.  |     .....|.|..|.||         .:|....:...|.||
Mouse   256 IERGSLMG--CSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRGSDDRPSRTIV 318

  Fly  1245 ---------------HAYSVLDVKD--IQGH--RLLKLRNPWGHYSWRGDWSDDSSLWT--DDLR 1288
                           |||||..:::  .:|.  :|::||||||...|.|.|||....|:  |...
Mouse   319 PVQYETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDE 383

  Fly  1289 DALMPHGASE-GVFWISFEDVLNYFDCIDICKVRSG---------W----NEVR-LQGTLQPLCS 1338
            .|.:.|..:| |.||:|::|.:.:|..::||.:.:.         |    ||.| ::|     ||
Mouse   384 KARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRG-----CS 443

  Fly  1339 I-SC------------VLLTVLE----PTEAEFT---LFQEGQRNSEKSQRSQLDLCVVIFRTRS 1383
            . .|            ..|.:||    |.::|..   |....|:|..|.::...:|..:.|
Mouse   444 AGGCRNFPDTFWTNPQYRLKLLEEDDDPEDSEVICSFLVALMQKNRRKDRKLGANLFTIGF---- 504

  Fly  1384 PAAPEIGR--------------LVEHSKRQVRGFVGCHKMLER-----DIYLLVCLAFNHWHTGI 1429
             |..|:.:              |...||.:.:.::...::.:|     ..|::|...:
Mouse   505 -AIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTY------- 561

  Fly  1430 EDPHQYPQCILAIHSSKRLLVEQISPSPHLLADAIISLTL-TKGQRHEGREGMTAYYLTKGWAGL 1493
             :|||..:.||.:.|.||.|.|:        |:..||:.. .|.::::.
Mouse   562 -EPHQEGEFILRVFSEKRNLSEE--------AENTISVDRPVKKKKNKP---------------- 601

  Fly  1494 VVMVENR-HENKWIHVKCDCQESYNVV--STRGELKT-----VDSVPPLQRQVIIVLTQLEG 1547
            ::.|.:| :.||.:.|..:.:|..:..  ..|||...     .|.....|:|...:..|:.|
Mouse   602 IIFVSDRANSNKELGVDQEAEEGKDKAGPEKRGETPQPRPGHTDQESEEQQQFRNIFRQIAG 663

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.