DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sol and capn8.6

DIOPT Version :9

Sequence 1:	NP_476738.3	Gene:	sol / 44014	FlyBaseID:	FBgn0003464	Length:	1594	Species:	Drosophila melanogaster
Sequence 2:	XP_031758229.1	Gene:	capn8.6 / 108647597	XenbaseID:	XB-GENE-22164427	Length:	466	Species:	Xenopus tropicalis

Alignment Length:	416	Identity:	106/416 - (25%)
Similarity:	175/416 - (42%)	Gaps:	94/416 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1015 FVDDSFPPAPKSLYYN---PASGAGEGNPVVQWRRPHEINCDGGAYPPWAVFRTPLPSDICQGVL 1076
            |.|..||.:..||..|   |.|...:|   :.|.||.||:              |.|..|..|..
Frog    33 FEDKEFPASQASLGSNKLGPESNTAKG---IVWLRPSEIH--------------PNPEFITSGAT 80

  Fly  1077 GN---CWLLSALAVLAEREDLVKEVLVTKEICG---QGAYQVRLCKDGKWTTVLVDDLLPCDKRG 1135
            .|   ...|||:..|...::.:..|:...:...   .|.:..||.:.|:|..|:|||:||...:.
Frog    81 QNVADSGFLSAMGSLTLNKEYLSLVVPQDQSFKTNYAGVFHFRLGQFGEWVDVVVDDILPTKDKK 145

  Fly  1136 HLVYSQAKRKQLWVPLIEKAVAKIHGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPMPSEDE 1200
            .:....|:..:.|..|:||||||:||.|||:.....|..|..|||..|||..|:::    |.:
Frog   146 LVFVKSAQENEFWPALLEKAVAKLHGSYEAISGNSLIIALEDLTGGVCESYSLKSA----PGD-- 204

  Fly  1201 LDKDLIWAQLLSSRCVRFLMGASCGGGNMKVDEEEYQQKGLRPRHAYSVLDVKDI---QGH-RLL 1261
                 ::..:..|...:.|:..|..|     .:|..::..:...|| |:...:::   :|. :|:
Frog   205 -----LFQTIQRSVRTQCLLTCSTNG-----KKEGAEKSSIVAGHA-SITGAEEVPYGKGKVQLI 258

  Fly  1262 KLRNPWGHYSWRGDWSDDSSLWTD---DLRDALMPHGASEGVFWISFEDVLNYFDCIDICKVRSG 1323
            :|:||||...|:|.|.|:...|.|   :::.||:  ...:|.||:.:.||:..::.::||.|.|.
Frog   259 QLQNPWGSAEWKGAWRDNGPEWNDVTPEVKKALL--NKEDGEFWMPYADVVKEYNTVEICYVASS 321

  Fly  1324 ---------WNEVRLQGTLQ-------------------------------PLCSISCVLL--TV 1346
                     |:..:.:|:..                               .||::...|:  ||
Frog   322 SGVNMKEPHWSLTQTEGSWNKGNPAETFLADPRFRFKLEVPDEDQAAAGDAALCTVIVALMQKTV 386

  Fly  1347 LEPTEAEFTLFQEGQRNSEKSQRSQL 1372
            .:....:|.|:|..:..|.|.|...|
Frog   387 PKDNYIDFQLYQLPKEVSSKVQVKDL 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sol	NP_476738.3	zf-RanBP	6..34	CDD:279035
		RanBP2-type Zn finger	10..29	CDD:275376
		zf-RanBP	135..164	CDD:279035
		zf-RanBP	643..672	CDD:279035
		RanBP2-type Zn finger	647..667	CDD:275375
		zf-RanBP	704..731	CDD:279035
		RanBP2-type Zn finger	708..727	CDD:275376
		zf-RanBP	747..774	CDD:279035
		RanBP2-type Zn finger	749..768	CDD:275376
		zf-RanBP	927..954	CDD:279035
		RanBP2-type Zn finger	931..950	CDD:275376
		CysPc	1001..1328	CDD:128526	93/337 (28%)
capn8.6	XP_031758229.1	Peptidase_C2	33..317	CDD:395523	89/319 (28%)
capn8.6	XP_031758229.1	Calpain_III	329..462	CDD:412194	14/84 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010