Protein Alignment ALG11 and Alg11

DIOPT Version :10

• Sequence 1: NP_001004127.2
• Gene: ALG11 / 440138
• HGNCID: 32456
• Length: 492
• Species: Homo sapiens
• Sequence 2: NP_649340.1
• Gene: Alg11 / 40402
• FlyBaseID: FBgn0037108
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 487
• Identity: 242/487 - (49%)
• Similarity: 323/487 - (66%)
• Gaps: 28/487 - (5%)

Human    17 FYSLFFPGLIVCGTLCVCLVIVL-------WGIRLLLQRKKKLVSTSKNGKNQMVIAFFHPYCNA 74
            |..||...|:    |.:.||.||       |    ||.||.||.::|:||.|   :..|||||||
  Fly     2 FLFLFLLWLL----LSLVLVAVLSFLFLRQW----LLGRKNKLHTSSENGIN---VGIFHPYCNA 55

Human    75 GGGGERVLWCALRALQKKYPEAVYVVYTGDVNVNGQQILEGAFRRFNIRL-IHPVQFVFLRKRYL 138
            |||||||||||:||||:||..|..|:||||::.:...||:.|...|||.: ...|:||||::|:.
  Fly    56 GGGGERVLWCAVRALQEKYQNARMVIYTGDIDASPNSILQKAKNVFNIAVDSDNVKFVFLKQRHW 120

Human   139 VEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFKYIGGCQVGSYVHYPTIS 203
            :|...||||||||||:||:.:|.|||.:..||:|||:||||||.|||:|:...:||.|||||.||
  Fly   121 IEAKNYPHFTLLGQSIGSMVVGLEALCRFPPDIYIDTMGYAFTYPLFRYLAQSKVGCYVHYPVIS 185

Human   204 TDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSL 268
            ||||..|:.:.:..||..::.|||||:..||.||.||:.:|..||.|::.:|||||||.||||.|
  Fly   186 TDMLKRVQQRQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQL 250

Human   269 WKVGNCTNIVYPPCDVQTFLDIPLHEKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVES 333
            |.|...|:.|||||:|.....:...||  ....:::|||||||||:||||::|..:|  :.::..
  Fly   251 WDVPFKTHRVYPPCEVSHLKSLQHTEK--GDEFIILSVGQFRPEKDHPLQLQAIYEL--RTLLAQ 311

Human   334 PPSL----KLVLIGGCRNKDDELRVNQLRRLSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHT 394
            ..:|    |||::|.|||:||..|:..::.|::.|.::..|:|.:|:|:::|......|.||:||
  Fly   312 DEALWNQIKLVIVGSCRNEDDYERLKNMQDLTKHLSLENNVQFSVNVPYEDLLKLYQTAHIGIHT 376

Human   395 MWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGDITGFLAESEEDYAETIAHILSMSAEK 459
            |||||||||:||.||||.|::||.||||.||||....|...||||....:|||.|.:|:..::|.
  Fly   377 MWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVETSAGSQNGFLATDAVEYAENILNIIVNNSEM 441

Human   460 RLQIRKSARASVSRFSDQEFEVTFLSSVEKLF 491
            . .||.:|||||.|||:||||..||.:|..||
  Fly   442 N-GIRNAARASVERFSEQEFEKNFLRAVSTLF 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALG11	NP_001004127.2	GT4_ALG11-like	63..480	CDD:340835	215/421 (51%)
Alg11	NP_649340.1	GT4_ALG11-like	44..463	CDD:340835	218/426 (51%)