DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sls and zormin

DIOPT Version :9

Sequence 1:	NP_001261304.1	Gene:	sls / 44013	FlyBaseID:	FBgn0086906	Length:	18468	Species:	Drosophila melanogaster
Sequence 2:	NP_001261317.1	Gene:	zormin / 2769001	FlyBaseID:	FBgn0052311	Length:	3664	Species:	Drosophila melanogaster

Alignment Length:	4522	Identity:	818/4522 - (18%)
Similarity:	1529/4522 - (33%)	Gaps:	1332/4522 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  4808 AEDESSSSGREDSAPESPHAFQPGQQPGQQFGQFLGVNGQGQHQGRSRQKKPKVRSKSLQ-PATK 4871
            |.|.|.||....::..:|:..||                   |.|...|.:...:|:..| .|..
  Fly     6 ALDSSMSSLYSVASSSNPNPRQP-------------------HTGHQLQTQQSQQSQQSQLDAFN 51

  Fly  4872 VIPWRKSSRPTRGRSLD--------KGVFLPGFKP---EPVKSWTEETINLKATPIE-----KKK 4920
            ......||.||..:::.        .|.......|   ..:::.|..|:.::..||:     .:.
  Fly    52 YSATMSSSSPTPSQAMSTAMSTGTGTGTGTTHTTPPSSSSLRATTIGTVVVRCGPIQLVIALLQS 116

  Fly  4921 PAPKLEAAKVVLKSIKTERDQGIMSLGATLEQIIAGKTEK-------EAIP-----WITMREKLK 4973
            |      .|:.:|.:  |.:..|.:||..|::.:..:.|.       :::|     ::...:||.
  Fly   117 P------EKIYIKVV--ELEPKITALGENLDESLRMQREHDETLRNLQSLPGPMDEFVQKADKLL 173

  Fly  4974 AVESVQQQLNKFDLDEV---------------------------------YLQPLEGQIETEGQL 5005
            |.:.:..:|.....|.:                                 .:..||...|.....
  Fly   174 ASKRISSELVNAMADTLNIIWQDILNLLQDRQHLLILCTQFHDKMTQCFRKMDQLELACEETLHP 238

  Fly  5006 PQQAQVEQ-VQRTKEIQRLKSMESV--------EIMEMTDQIDK---LITQQQNAK--------D 5050
            |...:|:: :.|.|:: |:..:..|        |::...::::|   |.|:.::.|        .
  Fly   239 PDVPRVQEFLNRFKQL-RIDMLTGVMAALKDGNELLAQLEELEKLETLDTRPEHIKRDATRAVHQ 302

  Fly  5051 LIPWKEMRQQLKSVQRVTKQIDKFKIEEV--------ELRHLQA--QQA---ITEEYQTGTAEET 5102
            :..|.|.....::...:..|..|.::|:.        ||..|:|  |||   :...|..|..|.|
  Fly   303 VQQWLEALHDRRNSLELAWQTRKIQMEQCLALALLGRELVDLEAALQQARMELNTMYSLGECEHT 367

  Fly  5103 VVMIDESSKGSISKVLRRDEQL-QYEDQSNIYKQKFITTEDVNIMHVSEREKLEAQRLIREQQAV 5166
            .                 :|.| :|.:    :||:.:...|..:.....:||:::.....|:.|
  Fly   368 A-----------------NEMLTKYRE----WKQQALLLRDRALKITRAKEKVQSAGHFTEEDA- 410

  Fly  5167 NWRQQQQRPQLQPLTSVEDTVISQTSERQKLVQQQSFIEEAQRQQFVQVEDSQMMSLEEYEHQKI 5231
                          .:....|:|..:|...||.|:.......|:.|.:.           ||...
  Fly   411 --------------CARAYAVLSGCTEHLDLVDQREHWLHQSREFFAKA-----------EHTVS 450

  Fly  5232 INQRTQQEAFSWR-QPREPQK---FIQVEDSTLLHLQERHDTQEQQLLQQQPVMWDRGRKKPDQP 5292
            :.::.:.|..|.: .|..|:.   |.:|:...      |:.|:|...|         |....|:.
  Fly   451 VLEKLELELTSVKLPPHSPESYAMFSKVDRDV------RNFTEEPLRL---------GYGILDEV 500

  Fly  5293 QYVQPQEQRVKE--EFVEKPKTYEEMHDELVEPTPIEQPQPVPVMWERGKKKPQPQEKTFEEAHD 5355
            ...||:.|.||.  :.:|..|.|               .|.:.......::|.|.....|...|:
  Fly   501 GRTQPETQGVKRVLDELENRKVY---------------IQGICANSSEDQQKVQRALSEFLNHHN 550

  Fly  5356 ELVEPTPVQQPEPVPVMWERGKKKVAQQETV-LSQEVVQTSQVVEQ--QIVEETKKTAVRRVIPP 5417
            ||             :.|.|...:...|::| :...:.|..|.:.|  :::::.
  Fly   551 EL-------------LAWLRASGQHQLQQSVDMGGNLQQAKQFLLQHHELMQDL----------- 591

  Fly  5418 REPEQKVEQVTLKPTPRPRPKEAVKAEEIQLKPLRSTRPVPQPVEAEQKAYEEATDELTEEPIPQ 5482
               |.|.|.:.|.       .|::|.....|.| :....|....|:..|.:.|..| |..:.:..
  Fly   592 ---EIKGELINLL-------LESIKVHLESLSP-QERYDVDSKAESLHKHWIELKD-LVLKRVDY 644

  Fly  5483 PQPVMWERGKKKPQKPQEEVTEIPKTLEIAVDTLEEEVPKPTEPQPQPVLWARGQKKPQKPDEQK 5547
            ...::             :..|:...|...:|.|:.::                   .|.|||.|
  Fly   645 VSLLI-------------DFFELANELSSQLDNLQRQL-------------------QQTPDEHK 677

  Fly  5548 QELPKSLEIAVDTIEEDL---------IKPVQPEPQPVLWERKKKKPQPQDVIEE--KLDVAPTK 5601
            .:..::....:.:...:|         :|.|.|     ..|.|......|:.:.:  |..|..|.
  Fly   678 LQFLQATWTGIASTFGELKSRGQRFINLKIVDP-----YLETKSSAQAVQETLNDFSKRQVDVTS 737

  Fly  5602 TYEKAVDVLPDEPKVEEKPEPVLWQRGKKKIPKSEPTEEVHPDEVDAQIETVVKEDEMIVEEKRR 5666
            :.|.....:.::.:||...|.|: ...::.:.||        .:||.|:..|.....  |:.|:.
  Fly   738 SLENWTTSIAEKREVEYLLEKVM-SDNEETVAKS--------TQVDTQLYPVFTSQS--VDSKQL 791

  Fly  5667 IKKTKRPKSTKEVTE-ELFEEQPEEEISPEEEVPQKE--VIEEIEEIVEEKRRLKKTKKPKLTQQ 5728
            :..| |.|.|..:.: |..:::.::.|.....:..|:  .:.:||:::...|.|    |.||...
  Fly   792 LIST-REKLTNVIQDIERAQDEIQQRIQTTLGIQTKDQPSLAKIEQVINNLRML----KAKLDGI 851

  Fly  5729 VTEEETPHEEIIKESEEVVQEQEEIVEEKKKVKKVKKPKTVAEKQLKEEEIPTEETVEEEETAED 5793
            ..:..|..|.:|:..|.:||.:.||  :....::.|:|.:.|::.:.|.|...::.::     :.
  Fly   852 KYDYRTLVESVIQFLENIVQLRREI--DDYFARQQKEPASGADRSIAEHEKFRDQCMD-----KF 909

  Fly  5794 QQLVVEESKKVKKVKKPTGTVEKTDVEELPGEEVPVEEVPVEEVPEDVAPEEELIEEQEEIVDQD 5858
            :.|:.:....:.:|:          |.|.||                 |.|          :|.|
  Fly   910 RSLITQSELLIDRVR----------VLEPPG-----------------ARE----------IDTD 937

  Fly  5859 EIQEQKRKVK-----KAKKPKKTIEKTEIEIEEDQPEEEVLQEEIIGEQEEITE-RQRKVKSIKK 5917
            .|.:....::     .:.....|:|:.| :||:.:.:.|.:...:....:::.| ..:.|.|:..
  Fly   938 RILKLLENLRLHFESNSSARMSTLERLE-KIEQFRSDLEDIDRSLDSVSQQLHEINNQSVDSLAA 1001

  Fly  5918 PKKV-----VTEKTVDQTEQPEKPEESQAEEVKETVTEEPKKPKPAPEEAKVEQVEKISLKPAPR 5977
            .|..     ..|:|:         |.|...::|.|                             |
  Fly  1002 AKTTSLAFEYFERTI---------ECSMPRQLKST-----------------------------R 1028

  Fly  5978 KQRLLPEKEQVEEVLLKPVKKIV-AVSEAEQPETPETEFEVKEFAITTTEDILDVTKKRVKKKKP 6041
            .||...:.....|:|.|.::|.. :.|:......||:|..||: .:....:.....|.:||:|:.
  Fly  1029 HQRRWGQTAHTIELLEKRIEKFTESTSQQLFITNPESERYVKD-ELRKLNEKWQSFKDQVKQKRK 1092

  Fly  6042 KTKVAAEESTEEPAEETEEFEEEATQPEEVQPVEEIPEEPQVKEVADERKTAPKPKPRKEEIIE- 6105
            ....|           |:.||          .||:|  :.:.:|::....:.....|...:.:|
  Fly  1093 SLNQA-----------TDFFE----------VVEKI--DAEYREISYFYTSVSNKVPYLRDSVEA 1134

  Fly  6106 -----KVEEVALKRVTRPKKELPQEA----TIEEVRLKPTQRTSIKPEEVKLEEVDLQHVEKKED 6161
                 .:|.....|....:.:|...:    .:.:|........:|....:||         |.:.
  Fly  1135 GNLVNDIENYVTSREAALRSKLDSASQCAHDMNKVSSLYNDVMNIFQSFIKL---------KMDI 1190

  Fly  6162 EIVQEEKRKTRKVKKPKHEDLPEIPDAEPT--QLEEAEHIELEKQPKPEEDQPQVPWKRGEKKQP 6224
            .:|||..::.::.|:.:..|..:..:.|..  :.|..|.:..|:|.:.|..:.|...::.:::..
  Fly  1191 NVVQERLKQEQRQKEQRERDARDQAEREKAIKEAEAKERLHREEQSRLENQRQQAAIEQAQRELA 1255

  Fly  6225 VEEVLEEKKWPSGKRRPLPEQ--QPEEVQLKPIPSKPIEEQQKPEKAIPGPQLVPEEKPESEEEE 6287
            ..|:            .|.||  :.||.:|:.|..:...||...|:|             :.|||
  Fly  1256 AREL------------ALREQAVREEEARLQAIREQATREQLAREQA-------------AREEE 1295

  Fly  6288 LELEPLKLPEDKKPKEPKAKKEKKKKPKLKKATPSVDEVSEEVAEPFDEPIAEEDEVEEMPVDDV 6352
            |.::.|:                                          .||..:  ||:.:.::
  Fly  1296 LRIQSLR------------------------------------------DIARRE--EEVRLQNI 1316

  Fly  6353 KVVAVSEDVLPEEEVVPTEETPEAKQKAHKKRTKRLKEASVEGQPQLLEAAIAEIEKVDEISQEI 6417
            :          :||.....|..|..::.::.|:||.:||.::.:         ||.::..:..::
  Fly  1317 R----------DEETRIRREEEERIRRENESRSKREEEARIQRE---------EITRLQTLRDQV 1362

  Fly  6418 SQKTITLLKKTEDTRPQFITTEQLIELDVEDVRRDLEMKVTSNIIKKEKRRVVLDDSQPLPELEL 6482
            .|:.|.                      .|::|:|:::.                        .:
  Fly  1363 DQQRIV----------------------TENIRKDIQVN------------------------SI 1381

  Fly  6483 ITQKRIQEGIDKVADEELIEDQQLIQNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQC 6547
            .|:.|...                                             |..|..|:....
  Fly  1382 FTELRYAS---------------------------------------------PLFTRPLKDAVS 1401

  Fly  6548 VPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKN 6612
            ...:..|.||:|.|.|.|.::|:.:.|.:..:..|:.|..:.:.:|.|.:...:|...::|.|.|
  Fly  1402 REGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASN 1466

  Fly  6613 EAGVATSRTNIILE-KEQGVPPQFTKPLKIEFIEE-KQPERLKVTVTCQVTGKPNPEVKWYRGIE 6675
            ..|  |..||..|. :|.....|...|..:.|::. |..|.......|.|.|.|.|.|:|::..:
  Fly  1467 LVG--TCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDK 1529

  Fly  6676 EVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREILKA 6740
            .:..|....:.|:  .|:..|:.......:..||:..|.|..|....:|:::..    |.|..:.
  Fly  1530 CIDDSPDYVISYN--NGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVE----PLEPTEL 1588

  Fly  6741 PTV-TPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTR 6804
            |:. .|||..:...|..:..||...|:|||||.|:.||:. .:..::..|....|..|.  ....
  Fly  1589 PSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKP-FQPRDSKYEYGRVTLIIP--QAYP 1650

  Fly  6805 KRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPL 6869
            ...|.|.:.|||..|||.:|.:|:|..:.|:|                          ..:||..
  Fly  1651 NDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNE--------------------------TSDSEMA 1689

  Fly  6870 SSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQE 6934
            |..      ||||.:
  Fly  1690 SDI------EPIKPA-------------------------------------------------- 1698

  Fly  6935 EAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQG-V 6998
                      |...::.|.:.:|:.:.|.|.:.|:|.|:|.||||...:.|:.:..:.  .|| .
  Fly  1699 ----------VHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLL--FQGDR 1751

  Fly  6999 CQLQITEVFPENEGQYECVATNKIGKSVSKTNVKIQAFEYIPDSEITGLTGSEEDLLDRTLSIDE 7063
            |.|.|.||:.|:.|.|:.||.|..|::.|...:|:     .|.::....|.::.:  .::|..|.
  Fly  1752 CSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKV-----TPLNQAEPATRAQAE--RQSLPKDS 1809

  Fly  7064 QAPKIIKKLPEKIEPKEGEQAKLEVKVVGKPKPKVKW------LRDDEQIFASEEYQIENFEDGT 7122
            | || .::|...:...||||..|||:..|......:|      |:.|::|....:.::     |.
  Fly  1810 Q-PK-FERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSEL-----GV 1867

  Fly  7123 SVLVINHVYPDDLGTISFEAYNPLGVAVTTALFAVEVKFFFRCLELHYLCFPNSLESSIVGSKDY 7187
            ..|::|:|..||.|..:.:..||.|.|                     .||.:.:..|:...::.
  Fly  1868 FKLILNNVSGDDKGVYTVKVTNPAGDA---------------------KCFSHLIVKSVNAPENR 1911

  Fly  7188 RKPEWVSQMEEMQVALKAAKCSPSLLNEMRDCRAALGETAKFSIQFAGNPIPDIQWYFNNVQLRA 7252
            |..:  |.:|    .::..:| |.......|.:..:.|..||.....|.|.|.:.|:||:..:.
  Fly  1912 RSSQ--SSVE----IIERHQC-PEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVH- 1968

  Fly  7253 SEKYRMVVQEQEATLEIMKITSEDCGYYNCKLINEIGMTMTRAKFDI--------SSTSTIVEE- 7308
            ...:.:....:...|.|.|:|.:..|..:|...||.|.....|..:|        |...|:.:|
  Fly  1969 GHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNIRGSGLPASSDVQTVSQEH 2033

  Fly  7309 --TKAKTTVKKKSGKKTMVKRSGASESQNVQKTEIRIIPTSA-VETSMNVIKVKQPVSVLVEKSE 7370
              ..::.|:||::...|...:..:.|. |..:||:.  .:|| ::.|:..:..::|  .:||...
  Fly  2034 NTESSRVTIKKQTFTTTSTSQVNSYEG-NAPQTEVH--HSSAHIDQSLKQLGQQRP--EIVESHH 2093

  Fly  7371 ISEVLVVKDREVADAEERSSQLIEE----------------------------------IEEEEE 7401
            ..|:...|:......:::|...|:.                                  :::..:
  Fly  2094 YQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRREIAPRFTTPLSGKIVDQGAD 2158

  Fly  7402 IEEKVQHDEEDEVEVQVEQKETYTSSKKIEITKTVELIRTKISEKI--ITIEDVQVLSHHEEVQW 7464
            :..:..:|.....|::||:..          .:..|...|:||.|.  :|||..||
  Fly  2159 VSMEAIYDGFPSPEIKVEKNG----------GQLFEDAHTRISNKCNRVTIELKQV--------- 2204

  Fly  7465 LLESIEAESFGQIGESALRDLATIGLLLRYGCEHYEITYMYEQNIFISLKKPESQSALVQLVERE 7529
                    ..|..|..|:....|:|          :.|...:..:..::..|.....|...|.::
  Fly  2205 --------GVGDAGRYAVTASNTVG----------QSTSTADLVVKKTIFPPVFGRRLQAQVSKK 2251

  Fly  7530 GHEELISQI----LSESS----NEDETILAATVGFKAFIRMIQTYEITIEIVIRKFVRED---FI 7583
            | |:|..::    |.|.:    .:|:.:..|.:.....:....:|.:.||    |....|   ::
  Fly  2252 G-EKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIE----KAQTTDSGKYM 2311

  Fly  7584 SQDWKICGKERIVETSQIIE-SHEAITHVKIEETFVEERTIIVQEETATTKVEKLFKKQEQEHVQ 7647
            .:.....|:.:.:....|:| |.|.:..|        .:||:.  ||........||.:.|:.:|
  Fly  2312 VRATNAGGEAKSIADCAILEPSPERLQEV--------VKTIVY--ETGPVAPASEFKTEVQKQIQ 2366

  Fly  7648 NLEQQEQVKIQVQTKQIAQMNTKIKKHKKHKQQEQEVSETTIQCEQKETLAHETSAELPQSETLE 7712
            |.|.|:..: ..||:..:..:.......|...:.:..:|.|::.|.|...     .:||:..|.
  Fly  2367 NSENQQSYQ-NSQTEVTSANDLHGLSESKVITEHRCTTEATMRLEHKSNY-----LDLPELTTR- 2424

  Fly  7713 QIEESLSTYETLPIQNLSKDTLQTVAVSV-------TTELSTPSPTASRVQEEILPQ---KVLAI 7767
              .::.:|.:|:.|      |..|..||:       .|..:|.:...::|...:.|:   .|:|.
  Fly  2425 --PKTPTTNDTITI------TTNTATVSMDQPDLTQPTITNTTTTNTTKVPPPVPPKPCTPVVAT 2481

  Fly  7768 NEEVLPLDEFGLRKESPRPKENKLTENIEVRLKHALNVSHAKTAESSKELPSKIPKSVKAQRKMK 7832
            .        ||.:::.|   ...||.....:.:|     .:.|:.||.:...||.:....||...
  Fly  2482 T--------FGQQQQQP---PQTLTSTRYEQSEH-----KSTTSSSSFDYFKKIDEETIIQRPNP 2530

  Fly  7833 ---ESRSLVVEAPNAEEAIEDLKPLKAVSQEVQSDILFSHEITEEQHQALETI-EKLKPTSAIED 7893
               :....||..|.|:...|:|:.|..:..:. .:..:|.: ||.....:..| ||:|
  Fly  2531 LTFKPLDTVVRQPQAQSLAEELRSLNLIPGDA-PEFCYSPK-TERSEPKIPLITEKIK------- 2586

  Fly  7894 TVQQKLLSQEELIIAEVLPSETVGRDVTDVRPPG---ETISPRLTPNMSLCITECQPEDSIGEMQ 7955
                        |::||.|.|...:....|.||.   :|:....|....:.:...||  .:....
  Fly  2587 ------------ILSEVQPKEPPPQGGVPVFPPPLGLQTVQHESTTTKEVKVEYGQP--IVRPAA 2637

  Fly  7956 QAAKERMETPSMSVTESKAVGGQELEVLENVDHMPLITQPTKGLADYTIKAEEVPVQVQEIITFD 8020
            ..|....:.|.....:..|.|..          |..:..|| |:..||...|:
  Fly  2638 VLATPAQQNPRSPSPKPSAEGVA----------MSRLWTPT-GVTGYTSDVEQ------------ 2679

  Fly  8021 SLERETVAK----TQTAKSNALELFELSEGLVSSTADSHSPIAEDLPIFEKDVKEATIDMQMQHH 8081
            ..|:..::|    |.|.:.||       ..||:..|.|..|
  Fly  2680 KSEKTVISKLATPTPTKELNA-------PFLVNQIAKSIPP------------------------ 2713

  Fly  8082 VTTSETVSNENAVKDLKAVDTPKMAEGTLGQSSALTIGETQQMNLVETTVELIEPNV-------- 8138
             ||:......|.  :|:....|::.       .|..:.||::.:||||..:.:|.|:
  Fly  2714 -TTAPVTHLVNV--ELEPGTPPEIC-------FAPKVEETRRRSLVETMEQKLEQNLIQGPSKVL 2768

  Fly  8139 ----------------------ESTKPAKGALTEAYGTAESNEETLLESLGLVPDDNRKIEQGKV 8181
                                  .:.:|....|....|..||:.|:          |..|....:.
  Fly  2769 PHSVPTLTPNTAAPVQPKPLGNTTYRPPPPVLPTRLGVYESDYES----------DRYKYSGSES 2823

  Fly  8182 NISEGEYVAKVQTTTVTDTEGEFVSVAPKLVNPKFDFVEQSALQIKQDTTVEKEEILSSNIELAP 8246
            ::..|  :.|....|..:|       :.|......|..|.|:.:..:.:..|.:.  ||.:..||
  Fly  2824 DVEPG--IRKQPQLTTMET-------SFKSSGYTADTEEHSSYRKSESSFYETKS--SSTMGGAP 2877

  Fly  8247 QLATSNMF-------PAELKVTSIYEVQPGL------TSSDIITEQTK----------------- 8281
            ||.|  .|       ||.:..|:  :.||.:      :.|::.:::.|
  Fly  2878 QLQT--QFPKLQPEPPAPIYFTA--KPQPQVPPQVPPSQSNVSSQEAKGYKYTSSSMTSNYSHNM 2938

  Fly  8282 -SVSANQVFETMSIGVTSKPDMLESTSHIDAFQH---PEFKTGDTILDENQQPLEVTNVQITESS 8342
             |.|::...||.....::.|.::...|.|.|.:.   .||....:.:||..:.:...|    ||.
  Fly  2939 QSSSSSSHHETKFSSTSAPPPVVTYPSPIPAQRKTPAAEFSDYSSEIDERFRSVSRAN----ESD 2999

  Fly  8343 TDIID---VLPNQKLTKAETVTDGFKYAEGLVVLPMESTIDKTED-------------------T 8385
            .:|..   |.|.....:....|:|.| :..:|:.|.....:.|..                   |
  Fly  3000 AEIKGYRVVFPPTPTPRTNIATNGHK-SPVVVITPSPMEFEPTPQDYARPKFEPISKEIRHEIKT 3063

  Fly  8386 KPTAVNADISMHQQFGTDVREQEPLES---TLTRTEDLK-PQTQTTESQF--GLLQSLETSSCVT 8444
            :.::..:....:||....|.:.:|:.:   ..|:.:..| ||..:..:.:  .:..:....:.|.
  Fly  3064 ETSSKQSKFMQNQQQNQPVFKPKPVAAKFIAATQQQQQKQPQATSRPTMYYNAVAGAPMHVAKVA 3128

  Fly  8445 LEGESVLSVKERHPEQSAAIGTSSALQVANITRPQHMESLDRLDEQK-------VPYYQANVNI- 8501
            .|.::|:.:.|         .|.|:.:|.|:.:.:.:...|...||:       .||..|....
  Fly  3129 TETKNVMQMHE---------STESSQRVVNMQQTKRIIHFDSPQEQRDQQILEPFPYSPATSRTP 3184

  Fly  8502 -GEITLPNVEKIDSFDVLSDLNTPDYNKSSKG-RVQLIES---------------------TTSL 8543
             .:..||.......| |..:....||.....| |:|.:.|                     :.||
  Fly  3185 SRQSHLPPPATPTKF-VPGEFRESDYESEIDGARIQPLWSPYGDGMTKGFRRVAPPQGAGRSCSL 3248

  Fly  8544 KTTTAVVSESTEELKDLNITQPVHIKPKPYESDQKISISEQTNVLEHVSSLNPVLPALETIQSSI 8608
            ..|...|....|..:...:...:|:.......:|:...:..|.  ....|||
  Fly  3249 PRTYERVLSPMEFDRGPEMPSKIHVDINTLRKEQRGGSTVTTQ--NRTQSLN------------- 3298

  Fly  8609 KSLHEINVRETDILEKEESLKDVDHISGRLAKIILDCTTGIAQVRQE---------ETLEHEEDL 8664
               ....:|:....::::|:..:|. :|.|.:.      |.:.::|:         .|...:...
  Fly  3299 ---RNTTMRQQQQQQQQQSMDQIDR-AGTLPRY------GYSSLQQQAENQGRRMGSTFLQKSHQ 3353

  Fly  8665 KAPLIPLEKAIPASSELH----RLPLTEYVQEQQGTSDMTDFKVS---NKCASPNIDHLY----- 8717
            ....:..|....||:.:.    |.|.....|:.|...|  :.:||   .||..||...:|
  Fly  3354 FVDDVSREIRSSASNGIRPGFKRAPSEGSSQQPQAFRD--ESRVSQYGTKCVDPNTGLIYFKYDF 3416

  Fly  8718 -------------ETKSSEMIVYDSS-------INSVDSEFPAGIVPQKSLV-PFRHTMVTENVA 8761
                         :..||:.....||       .|...|.:|..:.|...|| |.:|....:.
  Fly  3417 GYEFGILFPGEGHKFVSSQWNSSGSSNSNAKPIQNGRHSPYPLKLPPGNELVIPVQHERSAQG-- 3479

  Fly  8762 FNASENFEILSADQQIATNVQDSLSQSIIAEDQIAFETEQNLGLETTPTHKPKLLKDDQNLHAKL 8826
                     .|:|.::....|..           .:.|.:.:...|..:||...|....:|...|
  Fly  3480 ---------YSSDNEVQRRSQTR-----------NWSTTKPMAPRTINSHKRYSLPSGHSLDIHL 3524

  Fly  8827 VDEATVYEAMGQEQKVDKYNIQQAEITHD-----LPQVYATDLQQTFEAEKEITTREQSYVAATT 8886
                            |:.:.|...:..|     :|::..|:......:..|:..|:..::....
  Fly  3525 ----------------DRLHAQAPRLPPDQMIRTVPELPNTEPVNAHLSRDELAQRQPLFITPLK 3573

  Fly  8887 DIIPSRLGLAMTTKTHPVEGIDVLLSSPPKPSLAQTN 8923
            ||   .:|:..|.:      .:.::.:.|:|.:..|:
  Fly  3574 DI---AVGVGGTAR------FECIVQAHPQPQVNWTH 3601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sls	NP_001261304.1	I-set	87..174	CDD:254352
		Ig	109..175	CDD:143165
		Ig	254..334	CDD:299845
		I-set	255..344	CDD:254352
		I-set	372..462	CDD:254352
		Ig	390..463	CDD:299845
		Ig	471..561	CDD:299845
		I-set	471..560	CDD:254352
		I-set	618..709	CDD:254352
		Ig	645..705	CDD:143165
		DUF1136	715..741	CDD:284093
		IG_like	762..843	CDD:214653
		Ig	779..835	CDD:143165
		I-set	890..982	CDD:254352
		Ig	918..979	CDD:143165
		DUF1136	988..1014	CDD:284093
		I-set	1024..1116	CDD:254352
		Ig	1058..1113	CDD:143165
		I-set	1158..1250	CDD:254352
		Ig	1178..1246	CDD:143165
		DUF1136	1256..1282	CDD:284093
		I-set	1291..1380	CDD:254352
		IGc2	1304..1372	CDD:197706
		DUF1136	1388..1414	CDD:284093
		I-set	1424..1515	CDD:254352
		Ig	1442..1513	CDD:143165
		DUF1136	1522..1548	CDD:284093
		I-set	1558..1645	CDD:254352
		IGc2	1571..1639	CDD:197706
		DUF1136	1655..1679	CDD:284093
		I-set	1691..1782	CDD:254352
		IGc2	1718..1772	CDD:197706
		DUF1136	1788..1814	CDD:284093
		I-set	1824..1916	CDD:254352
		IGc2	1838..1906	CDD:197706
		DUF1136	1922..1948	CDD:284093
		I-set	1958..2049	CDD:254352
		Ig	1985..2044	CDD:143165
		I-set	2089..2181	CDD:254352
		IGc2	2103..2171	CDD:197706
		DUF1136	2187..2213	CDD:284093
		I-set	2222..2314	CDD:254352
		IGc2	2236..2304	CDD:197706
		DUF1136	2320..2346	CDD:284093
		I-set	2356..2448	CDD:254352
		Ig	2384..2445	CDD:143165
		DUF1136	2454..2480	CDD:284093
		I-set	2488..2580	CDD:254352
		Ig	2516..2576	CDD:143165
		I-set	2622..2714	CDD:254352
		IGc2	2636..2704	CDD:197706
		I-set	2754..2844	CDD:254352
		Ig	2771..2840	CDD:143165
		IGc2	2908..2974	CDD:197706
		I-set	3029..3120	CDD:254352
		Ig	3057..3116	CDD:143165
		I-set	3130..3220	CDD:254352
		Ig	3148..3219	CDD:143165
		I-set	3263..3354	CDD:254352
		I-set	3401..3493	CDD:254352
		Ig	3429..3490	CDD:143165
		I-set	3539..3630	CDD:254352
		Ig	3556..3625	CDD:143165
		I-set	3676..3767	CDD:254352
IGc2	3690..3758	CDD:197706
I-set	3811..3900	CDD:254352
Ig	3828..3899	CDD:143165
I-set	3954..4046	CDD:254352
Ig	3963..4042	CDD:299845
I-set	4092..4180	CDD:254352
Ig	4102..4172	CDD:299845
I-set	4394..4483	CDD:254352
Ig	4411..4480	CDD:143165
I-set	4497..4581	CDD:254352
Ig	4519..4580	CDD:143165
I-set	4604..4693	CDD:254352
Ig	4621..4691	CDD:299845
I-set	4702..4792	CDD:254352
Ig	4702..4791	CDD:299845
COG4372	4996..>5260	CDD:226809	55/301 (18%)
I-set	6536..6622	CDD:254352	22/85 (26%)
Ig	6554..6622	CDD:143165	19/67 (28%)
Ig	6654..6725	CDD:143165	16/70 (23%)
I-set	6743..6829	CDD:254352	28/86 (33%)
Ig	6760..6829	CDD:299845	24/68 (35%)
I-set	6841..6928	CDD:254352	7/86 (8%)
Ig	6858..6927	CDD:143165	7/68 (10%)
I-set	6942..7033	CDD:254352	29/91 (32%)
IGc2	6957..7023	CDD:197706	25/66 (38%)
I-set	7066..7157	CDD:254352	26/96 (27%)
Ig	7084..7153	CDD:143165	19/74 (26%)
IGc2	7224..7289	CDD:197706	17/64 (27%)
Ehrlichia_rpt	14571..15030	CDD:118064
SH3_p47phox_like	16753..16807	CDD:212790
I-set	16841..16931	CDD:254352
Ig	16858..16931	CDD:299845
I-set	16965..17060	CDD:254352
IGc2	16978..17050	CDD:197706
I-set	17068..17152	CDD:254352
Ig_2	17078..17152	CDD:290606
IG_like	17170..17253	CDD:214653
Ig	17180..17250	CDD:143165
I-set	17260..17342	CDD:254352
IGc2	17274..17331	CDD:197706
I-set	17347..17432	CDD:254352
IGc2	17367..17423	CDD:197706
I-set	17437..17521	CDD:254352
Ig	<17468..17521	CDD:299845
I-set	17528..17611	CDD:254352
Ig	17553..17602	CDD:143165
I-set	17618..17708	CDD:254352
Ig	17635..17708	CDD:299845
FN3	17712..17791	CDD:238020
I-set	17813..17898	CDD:254352
Ig	17830..17894	CDD:143165
Ig	17922..17994	CDD:299845
FN3	17998..18090	CDD:238020
FN3	18098..18189	CDD:238020
FN3	18207..18298	CDD:238020
FN3	18307..18398	CDD:238020
zormin	NP_001261317.1	SPEC	126..332	CDD:238103	31/206 (15%)
		SPEC	<504..641	CDD:295325	36/187 (19%)
		COG1340	960..1298	CDD:224259	79/434 (18%)
		RILP-like	<1190..1315	CDD:304877	33/193 (17%)
		MAP7	1233..1365	CDD:283355	36/219 (16%)
		I-set	1390..1479	CDD:254352	25/90 (28%)
		IGc2	1403..1469	CDD:197706	17/65 (26%)
		I-set	1491..1580	CDD:254352	21/90 (23%)
		IGc2	1504..1570	CDD:197706	16/67 (24%)
		I-set	1589..1675	CDD:254352	29/88 (33%)
		Ig	1605..1675	CDD:299845	24/72 (33%)
		I-set	1702..1786	CDD:254352	28/85 (33%)
		Ig	1713..1786	CDD:299845	26/74 (35%)
		I-set	1811..1902	CDD:254352	28/117 (24%)
		Ig	1828..1892	CDD:143165	17/68 (25%)
		I-set	1927..2015	CDD:254352	21/88 (24%)
		IGc2	1940..2005	CDD:197706	17/65 (26%)
		I-set	2142..2231	CDD:254352	20/125 (16%)
		Ig	2158..2231	CDD:299845	20/109 (18%)
		I-set	2238..2325	CDD:254352	16/91 (18%)
		Ig	2254..2324	CDD:299845	11/73 (15%)
		I-set	3566..3655	CDD:254352	7/45 (16%)
		Ig	3583..3650	CDD:143165	3/25 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45465017
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D4026at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.850