DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sls and Speg

DIOPT Version :9

Sequence 1:	NP_001261304.1	Gene:	sls / 44013	FlyBaseID:	FBgn0086906	Length:	18468	Species:	Drosophila melanogaster
Sequence 2:	XP_011236945.1	Gene:	Speg / 11790	MGIID:	109282	Length:	3272	Species:	Mus musculus

Alignment Length:	4037	Identity:	771/4037 - (19%)
Similarity:	1236/4037 - (30%)	Gaps:	1301/4037 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1290 APQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYVALDLLG 1354
            ||.|.|.|.|.....|::|.|  |:...|.|...:.||.:|:.:..     ||.|..  .|.|..
Mouse    44 APVFLRPLKNAAVCAGSDVRL--RVVVSGTPQPSLSWFRDGQLLPP-----PAPEPS--CLWLRS 99

  Fly  1355 CYAIDSGVYTCQARNQLGEA-----VTSCSVRII---AKNDLILETQNES-----GLQKIQYLED 1406
            |.|.|:|||:|.|:|:.|:|     :|...||:.   .|.....||..:.     |.|:::..:|
Mouse   100 CGAQDAGVYSCSAQNERGQASCEAVLTVLEVRVFRSCRKQSYDSETAEDDISDVPGTQRLELRDD 164

  Fly  1407 STRHRRSEFVDEVVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGH 1471
            ......:...|.:|.  ....|.|.|:|.|.|.                 :|.|:.:|:
Mouse   165 RAFSTPTGGSDTLVG--TSLDTPPTSVTGTSEE-----------------QVSWWGSGQ------ 204

  Fly  1472 RFRPIHDFGYVALDIVHLIAEDSGVYTCRAVNLIGSDETQVELQCRSGEQIVTVTQNEAGLEQIH 1536
                                                                ||.:.|||
Mouse   205 ----------------------------------------------------TVLEQEAG----- 212

  Fly  1537 YLEDRSRYTRREEIDESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLK 1601
                ....||  .:..|.:||.......:::.::...||. ...|:..|       |
Mouse   213 ----SGGGTR--PLPGSPRQAQTTGAGPRHLGVEPLVRAS-RANLVGAS-------W-------- 255

  Fly  1602 SGSRFTETNNFGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALP 1666
             ||                    ||:.:.....|.:...........:|            .::|
Mouse   256 -GS--------------------EDSLSVASDLYGSAFSLYRGRALSIH------------VSIP 287

  Fly  1667 RLQHLEDGSKRQRISVQDEFVSQA----PVFTMPVRDVRVAENQAVHFEARLIPVGDPKL----- 1722
                 ..|..|:...:|.:..|.|    |....|.:             :.|:|...|::
Mouse   288 -----PSGLHREEPDLQPQPASDALRPRPALPPPSK-------------SALLPPPSPRVGKRAL 334

  Fly  1723 -----------TVEWLRNGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVT 1776
                       |....|..:|....:.|||....|   ...|...|..:||...|....|.:|..
Mouse   335 PGPSTQPPATPTSPHRRAQEPSLPEDITTTEEKRG---KKPKSSGPSLAGTVESRPQTPLSEASG 396

  Fly  1777 SASLIVQSKTSIQLETQHEAAMHKIHQLEDHSRYQRREEEEYTVTTAPV-------FVTKLIGPS 1834
            ..|.:.:|...::..::   .:.|:...|:    :||..|......||:       ....|..|.
Mouse   397 RLSALGRSPRLVRAGSR---ILDKLQFFEE----RRRSLERSDSPPAPLRPWVPLRKARSLEQPK 454

  Fly  1835 NLVEGQSAHYECRIEPYPDPNLKVEWFHNGKPLSTGHRFRTTYDFGFAALDILTVYAEDSGEYTC 1899
            :  ||.:|        :..|....|...:  |..:....|..:....|:||..|.....:.:...
Mouse   455 S--EGGAA--------WGTPEASQEELRS--PRGSVAERRRLFQQKAASLDERTRQRSATSDLEL 507

  Fly  1900 RVTNNLGEAINSIVLNVTSRSSIIHETQHEEALTKIQHLEDTSRFQRKTDEEQFHAERPQFGRPL 1964
            |....||....|     |||..::.  .||.....:|          :....:...|.|.|.||.
Mouse   508 RFAQELGRIRRS-----TSREELVR--SHESLRATLQ----------RAPSPREPGEPPLFSRPS 555

  Fly  1965 RNAKVNEGAPVHLEATLIPV--------NDPTMKVEWYCNGRPIQTGHRFKTTYDFGFVALDILY 2021
            ........:|.   ||..|.        ::|         |||...|...:|....|      ..
Mouse   556 TPKTSRAVSPA---ATQPPPPSGAGKSGDEP---------GRPRSRGPVGRTEPGEG------PQ 602

  Fly  2022 AHAEDTGTYMCKAKNAIGEA---VTTCAVNVTANKTLDLDTLDAQRLEKIRQLETYAPPPKPVVE 2083
            ...:....:......||.|.   |.....:...::|   .....::.|...|...:.|...|.||
Mouse   603 QEIKRRDQFPLTRSRAIQECRSPVPPYTADPPESRT---KAPSGRKREPPAQAVRFLPWATPGVE 664

  Fly  2084 EKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPINDPNLKIEWFCNGKQLPTGHRYRTTHDFGYVA 2148
            :.      :.| ..||..:.|..|....|..|..|.    .|
Mouse   665 DS------VLP-QTLEKNRAGPEAEKRLRRGPEEDG----PW----------------------- 695

  Fly  2149 LDILYVYGEDTGTYICKATNQLGEAVNTCNVRVLNRRSMILDTQHPDALEKIQKLESKVPNARTE 2213
                       |.:..:.|...|:          .||:      .|.:.|    |||. .::...
Mouse   696 -----------GPWDRRGTRSQGK----------GRRA------RPTSPE----LESS-DDSYVS 728

  Fly  2214 VGDAPISPPHFTAELRGSTEIYEGQTAHFEAQVAPVHD----------PNLRIEFYHNGKPLPSA 2268
            .|:.|:..|.|...|:...             |||..|          |..::.:..:|..|.|.
Mouse   729 AGEEPLEAPVFEIPLQNMV-------------VAPGADVLLKCIITANPPPQVSWKKDGSMLHSE 780

  Fly  2269 SRFHITFDFGYVSLDITHAVAEDAGEYSVRAVNALGQAVSSTNLRVIPRGT-------IISDTQH 2326
            .|..|..:....:|.:..|.|.|||.|:..|.|.||||..:::|.|.|.|:       |.||.::
Mouse   781 GRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQATCASSLAVRPGGSTSPFSSPITSDEEY 845

  Fly  2327 PEGLEKIRKLEST---------APHQRQEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIP 2382
            ....|:..:...|         :|.|..:.....::..|.|...|.: ..:.|.|......|:
Mouse   846 LSPPEEFPEPGETWPRTPTMKLSPSQDHDSSDSSSKAPPTFKVSLMD-QSVREGQDVIMSIRV-- 907

  Fly  2383 VGDPNLKVEWYRNEKIIE-DSSRITKQHDFGFVSLDISHIRKEDEGVYMCRAVNPLGEAVTTASM 2446
            .|:|...|.|.||.:.:. |..|..::.:.|...|.|....:.|.|.|.|:|||..|.....|.:
Mouse   908 QGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARL 972

  Fly  2447 RVVSEASIQMDTQHPDSISRIHQLEKPLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEAR 2511
            .|         ..||:|.|.     ..|||.........|..:|..|:.||::
Mouse   973 EV---------RAHPESRSL-----AVLAPLQDVDVGAGEMALFECLVAGPAD------------ 1011

  Fly  2512 VVPVGDPSLKFEWFINGVELQMG-SRLRTTHDFGFVTLDITAVVPEDAGVYMCRAYNAAGEAVSS 2575
                    ::.:|...|..||.. .:.:...|.....|.:|:|..:|:|||.|:...|..|...|
Mouse  1012 --------VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCS 1068

  Fly  2576 TAMKVKTKSNIDGQPLIPESWEAIRLKEAAMNRVPEMFVDSTPQQAPVFTTHLQSYDKLHEGQHV 2640
            ..:.|:                                    |..||:||..|:..:.| ||:..
Mouse  1069 ARLTVR------------------------------------PSLAPLFTRLLEDVEVL-EGRAA 1096

  Fly  2641 LLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGE 2705
            .|:.::.....|:  :.|...|..:..|..:|...|.||.:|.|..:.::|..:|...|||..|:
Mouse  1097 RLDCKISGTPPPS--VTWTHFGHPVNEGDNLRLQQDGGLHSLHIARVGSEDEGLYEVSATNTHGQ 1159

  Fly  2706 AVSTSSLKIED-RHWLQAESLHPDSLPRIGELEAPKEGRPEAPE----PTYETPVFITHLNNIEC 2765
            |..::.|.:|: |......|...:.:|.|          ||.||    .....|.|:..|.::|.
Mouse  1160 AHCSAQLYVEEPRTAASGPSSKLEKMPSI----------PEEPEHGDLERLSIPDFLRPLQDLEV 1214

  Fly  2766 KESDNVRFECNVEPARDPTMSIEWFYNGQPLQAA-----AKFKSIYDFGYCALDLTNSYAENSGV 2825
            ..:.....||.|.....||:|  ||:||..:|::     .:::.|:...:.|:.     .:::||
Mouse  1215 GLAKEAMLECQVTGLPYPTIS--WFHNGHRIQSSDDRRMTQYRDIHRLVFPAVG-----PQHAGV 1272

  Fly  2826 YTCKATNSKGSATTSGTLKCTGGKTMFLDTQHPQGEAGLEAVQETEEELANRYTSKTTKPETQYP 2890
            |.....|..|.|.....|..|.     :....|.|...:.||       ..|..:.:..|
Mouse  1273 YKSVIANKLGKAACYAHLYVTD-----VVPGPPDGAPEVVAV-------TGRMVTLSWNP----- 1320

  Fly  2891 PPVWTKPLQAEFHLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMTSEFGFVTMDMI 2955
                              |..|:..::|
Mouse  1321 ------------------PRSLDMAIDP------------------------------------- 1330

  Fly  2956 EVYARDQGIYTCKAYNKAGEAFTSTTIFCSSKENIIESTQHPKGA-----EGLEQIQDLEDSLRK 3015
                 |...||.:......:.:|:          ::...:.|..|     :|::.|..:..|..|
Mouse  1331 -----DSLTYTVQHQVLGSDQWTA----------LVTGLREPAWAATGLKKGIQHIFRVLSSSGK 1380

  Fly  3016 DGSKPEQPDLGI------PPRFTTEFV----NIADIGEGELA-------HFEANLIPVGDQSMVI 3063
            ..|||..|...:      ||......|    :|..:.||:.|       |.||.::
Mouse  1381 SSSKPSAPSEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVV--------- 1436

  Fly  3064 EW-FYNGKVLEASHRVRT-IYAFG-----TVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLEC 3121
             | ...|.:|||    || :|...     ...|.:......|.|..||.|.|:|||...|..||.
Mouse  1437 -WRSCRGALLEA----RTGVYELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSVTLEL 1496

  Fly  3122 VDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFG 3186
                 .:.|||.|.::.:| :..|::|.|...:.....||  :.||.:..|:..||.:..|.:..
Mouse  1497 -----AEAPRFESIMEDVE-VGPGETARFAVVVEGKPLPD--IMWYKDEVLLAESNHVSFVYEEN 1553

  Fly  3187 YVVLDISYLQDHDSGEYVCRAWNKYGEDFTRTTLN-CGGRGGVFYDSLQPDSLQRIRELECPQGQ 3250
            ...|.:......|.|.|.|.|.|..||...:..|: ...:..:..:.:..|...|.|.|    ..
Mouse  1554 ECSLVLLSAGSQDGGVYTCTARNLAGEVSCKAELSVLSAQTAMEVEGVGEDEEHRGRRL----SD 1614

  Fly  3251 QADTSAPLVAEPPKFITQIVD-------VTKLVEGQ-----SAHFEARLTPITDPDLVVEWYFNG 3303
            ..|....:......::.::|:       ..|.:..|     ||..||||.
Mouse  1615 YYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARREARLL--------------- 1664

  Fly  3304 KKLPHGHRFRTFHDF-----GIVILDILYCYEENSGVYEARARNKYGEDVTRASLKCASKSSLIL 3363
            .:|.|| ....||:.     |:||:..| |.||   :.|..||                 ...:.
Mouse  1665 ARLQHG-CVLYFHEAFERRRGLVIVTEL-CTEE---LLERMAR-----------------KPTVC 1707

  Fly  3364 DSQLPRGMEGGLEKIANLEYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPA 3428
            :|:....|...||.|..|..|.|...:...                 |||...:.|..|.::...
Mouse  1708 ESETRTYMRQVLEGICYLHQSHVLHLDVKP-----------------ENLLVWDGAGGEEQVRIC 1755

  Fly  3429 DDPKLKVEWYWNGRPLKAGSRFRTFCDFG---FVILEI---SPV------YPEDSGEYSC-RAIN 3480
            |        :.|.:.|..|.  ..:|.:|   ||..||   |||      :|.....:.| ..|:
Mouse  1756 D--------FGNAQELTPGE--PQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGIS 1810

  Fly  3481 EY-GEAVTTATMKIQGKRSIIMES---QLPKGMEGTIDRIAELEGLGSRSTEFVPDDDTGKPPEF 3541
            .: ||...|..|.|:.......|:   .|.:...|.:.::            .|.|
Mouse  1811 PFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKV------------LVQD--------- 1854

  Fly  3542 ITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTINDFGFVILEIAGCYQR 3606
                               ||:|..:.::...||   |....|:.:.|.:
Mouse  1855 -------------------RLRPTAEETLEHPWF---KTEAKGAEVSTDH--------------- 1882

  Fly  3607 DSGLYTCKATNKHGEATVSCKLQVKGRQGIVMEP-----------QLPSNFRTGTESLQKLEETM 3660
             ..|:..:...:..:.:..|.|.::....::..|           |.||.   |..|....||
Mouse  1883 -LKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRRQPPSG---GLSSSSDSEE-- 1941

  Fly  3661 HKREELVTEDEQPNP--PKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGS 3723
               |||......|.|  |:|:.......|:|        ...|.:|.|             ..|:
Mouse  1942 ---EELEELPSVPRPLQPEFSGSRVSLTDIP--------TEDEALGTP-------------EAGA 1982

  Fly  3724 RVHQLNDFGFIALDVDYIYARDSGEYTCRATNKWGTATTSAKVTCKGKHNIVYESQLPEGMTSEK 3788
                       |..:|:       :...|..:|...|.:...:...|:.:       |:| .|.:
Mouse  1983 -----------ATPMDW-------QEQERTPSKDQEAPSPEALPSPGQES-------PDG-PSPR 2021

  Fly  3789 LKELERGRIPEA--PKVVEEVFG----------------PPKFTTQITSVTVDEAE-AVRFECQV 3834
            ..||.||...|:  |:|.....|                |....|::|...:.|.| |.|.:
Mouse  2022 RPELRRGSSAESALPRVGSREPGRSLHKAASVELPQRRSPSPGATRLTRGGLGEGEYAQRLQ--- 2083

  Fly  3835 EPKTDPSLRVEWYRNGKPLP-----SGHRYRNIFDMGFVSLDILYVYGEDSGEYVCRAINNYGED 3894
                  :||....|.|   |     ||.|...:..:|..:.|                      .
Mouse  2084 ------ALRQRLLRGG---PEDGKVSGLRGPLLESLGGRARD----------------------P 2117

  Fly  3895 RTRATVSCKKLPTILLQNQVP---RGMKRSDALTQMEA-----------------------TIKK 3933
            |.....|.:..|    .:|.|   ||:::|.:.:|.||                       .:::
Mouse  2118 RMARAASSEAAP----HHQPPPESRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQE 2178

  Fly  3934 YTSEVHLTEDDLFDPDRKQPPRF-VTQIKEQLTLTEM-AVTKFECQLAPVGDPNMKVEWFFNGK- 3995
            ..|...|:|.....|.|...|:. :|:..|...:|.. :....|.|..|...|..|.|.....|
Mouse  2179 SPSLSALSETQPPSPARPSVPKLSITKSPEPSAVTSRDSPQPPEPQPVPEKVPEPKPEPVRAAKP 2243

  Fly  3996 ---PLLHKNRFQPIYDFGYV----AMNFGWVYPEDSGEYVCRATNLYGKDETRAIIKVSGKPGIV 4053
               ||..:...||:..:..:    .::...:.|:|..     ......|.......:|:..|..|
Mouse  2244 AQPPLALQMPTQPLTPYAQIMQSLQLSSPTLSPQDPA-----VPPSEPKPHAAVFARVASPPPGV 2303

  Fly  4054 YDSQLPAHMQSIDRIREMEASWQVVPDEVDPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGH 4118
            .:.::|:                           .||.||...|....||.
Mouse  2304 SEKRVPS---------------------------ARTPPVLAEKARVPTVP-------------- 2327

  Fly  4119 PRPRVMWLINGHTVVHGSRYKLTNDGMFHLDVPKTRQYDTGKVEVIARNSVGESIATTELKVVAR 4183
            |||        .:.:.||...|.::.:|.....::|                ||..:..|::::|
Mouse  2328 PRP--------GSSLSGSIENLESEAVFEAKFKRSR----------------ESPLSRGLRLLSR 2368

  Fly  4184 SDDYRNVLKNSPRPWYDYELAAYQKERQENELEKVFDERKQVLSEQSSHTLKGVEHLKPKQYKPP 4248
            |                       :..:........|:              |:       |:|.
Mouse  2369 S-----------------------RSEERGPFRGAEDD--------------GI-------YRPS 2389

  Fly  4249 ---TPDWQQNVKAKKSEDYYNKLQTLETEQLLKETNLRRDTHQYAIPGEKVVSSSQAKGMAQSYE 4310
               ||                    ||   |::.....|......:.||        .|:.:...
Mouse  2390 PAGTP--------------------LE---LVRRPERSRSVQDLRVAGE--------PGLVRRLS 2423

  Fly  4311 ENLQEKTSTTEVQAAPPKGIAQPS--------ESSVHGREVHMNKQQQVQKEIQGDLEITRKITA 4367
            .:|.:|...|      |.|...|:        |||..|.....:....|::.:...||
Mouse  2424 LSLSQKLRRT------PPGQRHPAWESRSGDGESSEGGSSARASPVLAVRRRLSSTLE------- 2475

  Fly  4368 TETTEVEHKGTIQERVVQGPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESF 4432
            ..::.::..|:.::   .|.......|:|.:
Mouse  2476 RLSSRLQRSGSSED---SGGASGRSTPLFGR---------------------------------- 2503

  Fly  4433 PIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPP 4497
                   |:..|..|:|   :|::.|..:.:.|    ..|.|...:.:|..|   .:|..|...|
Mouse  2504 -------LRRATSEGES---LRRLGVPHNQLGS----QTGATTPSAESLGSE---ASGTSGSSAP 2551

  Fly  4498 SFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE 4562
            .     :|.:.....|:|.              .|:....||::. ..::||..|..:
Mouse  2552 G-----ESRSRHRWGLSRL--------------RKDKGLSQPNLS-SSVQEDLGHQYV------- 2589

  Fly  4563 DSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRV 4627
                                      ||:.:.|        |....:||.|.:.||......|..
Mouse  2590 --------------------------PSESDFP--------PVFHIKLKDQVLLEGEAATLLCLP 2620

  Fly  4628 DGKPTPTARWMRGENFVK--PSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 4690
            ...|.|...||:.:..::  ||......:.|... |.|..|.....|.|:|.|.|.||||.:|..
Mouse  2621 AACPAPRISWMKDKQSLRSEPSVVIVSCKDGRQL-LSIPRAGKRHAGLYECSATNVLGSITSSCT 2684

  Fly  4691 LKVRPIENLDAPPTI-TALKDVSVTEGMPAQFKT----TVTGKVKATSVQWFREGQLIPETPDFQ 4750
            :.|..|....|||.: ....|.::....|...:.    |:..:|...|| |......||:.
Mouse  2685 VAVARIPGKLAPPEVPQTYHDTALVVWKPGDGRAPCTYTLERRVDGESV-WHPVSSGIPDC---- 2744

  Fly  4751 MIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQ---VESSAKLTVKKRRISAFQLRTIDSAEDES 4812
               ..|...|.:|.|..     |.|..::..||   ...|.|:.::....|..|  ...:..|..
Mouse  2745 ---YYNVTQLPVGVTVR-----FRVACSNRAGQGPFSNPSEKVFIRGTPDSPAQ--PAAAPRDAP 2799

  Fly  4813 SSSG-REDSAPESPHAFQPG---QQPGQQFGQFL-GVNGQGQHQGRSRQK-------KPKVRSKS 4865
            .:|| .....|:||.:..|.   ..|..|..... ..:....:|..|..|       .|..:.:.
Mouse  2800 VTSGPTRAPPPDSPTSLAPTPALAPPASQASTLSPSTSSMSANQALSSLKAVGPPPATPPRKHRG 2864

  Fly  4866 LQPATKVIPWRKS--SRPTRGRSL--DKGVFLPGFKPEPVKSWTEETINLKATPIEKKKPAPKL- 4925
            |....:..|...|  ..|:..||.  |.|...|...|:.||.....|.....|......|||:.
Mouse  2865 LLATQQAEPSPPSIVVTPSEPRSFVPDTGTLTPTSSPQGVKPAPSSTSLYMVTSFVSAPPAPQAP 2929

  Fly  4926 ------EAAKVVLKSIKTERDQGIMSL----GATLEQIIAGKTEKEAIPWITMREKLKAVESVQQ 4980
                  |..||.::|:...::  ::|.    ..||.|   |..:|   |:..:.||.:....|.:
Mouse  2930 APEPPPEPTKVTVRSLSPAKE--VVSSPTPESTTLRQ---GPPQK---PYTFLEEKARGRFGVVR 2986

  Fly  4981 QLNKFDLDEVYLQPLEGQIETEGQLPQQAQVEQVQRTKEIQRLKSMESVEIMEMTDQIDKLITQQ 5045
            ...:......::..:. ....||: .:..|..:|.||...:||.|:....|   |.:...||.:.
Mouse  2987 SCRENATGRTFVAKIV-PYAAEGK-RRVLQEYEVLRTLHHERLMSLHEAYI---TPRYLVLIAES 3046

  Fly  5046 QNAKDLI 5052
            ...::|:
Mouse  3047 CGNRELL 3053

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sls	NP_001261304.1	I-set	87..174	CDD:254352
		Ig	109..175	CDD:143165
		Ig	254..334	CDD:299845
		I-set	255..344	CDD:254352
		I-set	372..462	CDD:254352
		Ig	390..463	CDD:299845
		Ig	471..561	CDD:299845
		I-set	471..560	CDD:254352
		I-set	618..709	CDD:254352
		Ig	645..705	CDD:143165
		DUF1136	715..741	CDD:284093
		IG_like	762..843	CDD:214653
		Ig	779..835	CDD:143165
		I-set	890..982	CDD:254352
		Ig	918..979	CDD:143165
		DUF1136	988..1014	CDD:284093
		I-set	1024..1116	CDD:254352
		Ig	1058..1113	CDD:143165
		I-set	1158..1250	CDD:254352
		Ig	1178..1246	CDD:143165
		DUF1136	1256..1282	CDD:284093
		I-set	1291..1380	CDD:254352	31/93 (33%)
		IGc2	1304..1372	CDD:197706	23/67 (34%)
		DUF1136	1388..1414	CDD:284093	5/30 (17%)
		I-set	1424..1515	CDD:254352	9/90 (10%)
		Ig	1442..1513	CDD:143165	3/70 (4%)
		DUF1136	1522..1548	CDD:284093	7/25 (28%)
		I-set	1558..1645	CDD:254352	10/86 (12%)
		IGc2	1571..1639	CDD:197706	10/67 (15%)
		DUF1136	1655..1679	CDD:284093	3/23 (13%)
		I-set	1691..1782	CDD:254352	20/106 (19%)
		IGc2	1718..1772	CDD:197706	13/69 (19%)
		DUF1136	1788..1814	CDD:284093	3/25 (12%)
		I-set	1824..1916	CDD:254352	18/98 (18%)
		IGc2	1838..1906	CDD:197706	12/67 (18%)
		DUF1136	1922..1948	CDD:284093	3/25 (12%)
		I-set	1958..2049	CDD:254352	19/101 (19%)
		Ig	1985..2044	CDD:143165	11/61 (18%)
		I-set	2089..2181	CDD:254352	12/91 (13%)
		IGc2	2103..2171	CDD:197706	8/67 (12%)
		DUF1136	2187..2213	CDD:284093	5/25 (20%)
		I-set	2222..2314	CDD:254352	27/101 (27%)
		IGc2	2236..2304	CDD:197706	19/77 (25%)
		DUF1136	2320..2346	CDD:284093	7/34 (21%)
		I-set	2356..2448	CDD:254352	26/92 (28%)
		Ig	2384..2445	CDD:143165	19/61 (31%)
		DUF1136	2454..2480	CDD:284093	7/25 (28%)
		I-set	2488..2580	CDD:254352	20/92 (22%)
		Ig	2516..2576	CDD:143165	15/60 (25%)
		I-set	2622..2714	CDD:254352	26/91 (29%)
		IGc2	2636..2704	CDD:197706	18/67 (27%)
		I-set	2754..2844	CDD:254352	23/94 (24%)
		Ig	2771..2840	CDD:143165	19/73 (26%)
		IGc2	2908..2974	CDD:197706	6/65 (9%)
		I-set	3029..3120	CDD:254352	28/108 (26%)
		Ig	3057..3116	CDD:143165	18/65 (28%)
		I-set	3130..3220	CDD:254352	25/89 (28%)
		Ig	3148..3219	CDD:143165	19/70 (27%)
		I-set	3263..3354	CDD:254352	24/107 (22%)
		I-set	3401..3493	CDD:254352	25/105 (24%)
		Ig	3429..3490	CDD:143165	19/74 (26%)
		I-set	3539..3630	CDD:254352	11/90 (12%)
		Ig	3556..3625	CDD:143165	9/68 (13%)
		I-set	3676..3767	CDD:254352	13/90 (14%)
IGc2	3690..3758	CDD:197706	8/67 (12%)
I-set	3811..3900	CDD:254352	17/94 (18%)
Ig	3828..3899	CDD:143165	12/75 (16%)
I-set	3954..4046	CDD:254352	18/101 (18%)
Ig	3963..4042	CDD:299845	15/87 (17%)
I-set	4092..4180	CDD:254352	16/87 (18%)
Ig	4102..4172	CDD:299845	10/69 (14%)
I-set	4394..4483	CDD:254352	12/88 (14%)
Ig	4411..4480	CDD:143165	9/68 (13%)
I-set	4497..4581	CDD:254352	10/83 (12%)
Ig	4519..4580	CDD:143165	6/60 (10%)
I-set	4604..4693	CDD:254352	27/90 (30%)
Ig	4621..4691	CDD:299845	21/71 (30%)
I-set	4702..4792	CDD:254352	21/97 (22%)
Ig	4702..4791	CDD:299845	21/96 (22%)
COG4372	4996..>5260	CDD:226809	14/57 (25%)
I-set	6536..6622	CDD:254352
Ig	6554..6622	CDD:143165
Ig	6654..6725	CDD:143165
I-set	6743..6829	CDD:254352
Ig	6760..6829	CDD:299845
I-set	6841..6928	CDD:254352
Ig	6858..6927	CDD:143165
I-set	6942..7033	CDD:254352
IGc2	6957..7023	CDD:197706
I-set	7066..7157	CDD:254352
Ig	7084..7153	CDD:143165
IGc2	7224..7289	CDD:197706
Ehrlichia_rpt	14571..15030	CDD:118064
SH3_p47phox_like	16753..16807	CDD:212790
I-set	16841..16931	CDD:254352
Ig	16858..16931	CDD:299845
I-set	16965..17060	CDD:254352
IGc2	16978..17050	CDD:197706
I-set	17068..17152	CDD:254352
Ig_2	17078..17152	CDD:290606
IG_like	17170..17253	CDD:214653
Ig	17180..17250	CDD:143165
I-set	17260..17342	CDD:254352
IGc2	17274..17331	CDD:197706
I-set	17347..17432	CDD:254352
IGc2	17367..17423	CDD:197706
I-set	17437..17521	CDD:254352
Ig	<17468..17521	CDD:299845
I-set	17528..17611	CDD:254352
Ig	17553..17602	CDD:143165
I-set	17618..17708	CDD:254352
Ig	17635..17708	CDD:299845
FN3	17712..17791	CDD:238020
I-set	17813..17898	CDD:254352
Ig	17830..17894	CDD:143165
Ig	17922..17994	CDD:299845
FN3	17998..18090	CDD:238020
FN3	18098..18189	CDD:238020
FN3	18207..18298	CDD:238020
FN3	18307..18398	CDD:238020
Speg	XP_011236945.1	I-set	45..127	CDD:369462	30/90 (33%)
		PHA03247	<320..697	CDD:223021	85/481 (18%)
		I-set	737..826	CDD:369462	27/101 (27%)
		SPEG_u2	827..883	CDD:293256	9/55 (16%)
		I-set	884..974	CDD:369462	26/92 (28%)
		Ig	988..1073	CDD:386229	22/104 (21%)
		I-set	1079..1168	CDD:369462	26/91 (29%)
		I-set	1203..1292	CDD:369462	24/95 (25%)
		FN3	1297..>1374	CDD:238020	17/158 (11%)
		I-set	1500..1589	CDD:369462	26/91 (29%)
		STKc_SPEG_rpt1	1613..1869	CDD:271010	67/359 (19%)
		PHA03247	<1951..2355	CDD:223021	96/542 (18%)
		PHA03307	2235..>2557	CDD:223039	78/538 (14%)
		I-set	2597..2687	CDD:369462	27/90 (30%)
		FN3	2691..2777	CDD:238020	20/98 (20%)
		PHA03247	<2760..2981	CDD:223021	50/230 (22%)
		STKc_SPEG_rpt2	2967..3223	CDD:271013	19/95 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0613
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810