DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgm1 and PGM2

DIOPT Version :9

Sequence 1:	NP_524675.1	Gene:	Pgm1 / 44010	FlyBaseID:	FBgn0003076	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001154465.1	Gene:	PGM2 / 843410	AraportID:	AT1G70730	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	315/591 - (53%)
Similarity:	414/591 - (70%)	Gaps:	38/591 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLTVEIVATKPYEGQKPGTSGLRKKVKVFTQPNYTENFVQAILEA-NGAALAGSTLVVGGDGRF 64
            :|..|.:|:|.|.:||||||||||||||||.||||.||||||...| ....:.|:||||.||||:
plant    79 VSFKVSLVSTSPIDGQKPGTSGLRKKVKVFKQPNYLENFVQATFNALTTEKVKGATLVVSGDGRY 143

  Fly    65 YCKEAAELIVRLSAANGVSKLLVGQNGILSTPAVSSLIRH------NKALGGIVLTASHNPGGPE 123
            |.::|.::||:::|||||.::.||||.:|||||||::||.      :||.|..:||||||||||.
plant   144 YSEQAIQIIVKMAAANGVRRVWVGQNSLLSTPAVSAIIRERVGADGSKATGAFILTASHNPGGPT 208

  Fly   124 NDFGIKFNCENGGPAPDAFTNHIYKITTEIKEYKLVRNL-QIDISKVGVTSFDIAGKPFTVEVID 187
            .|||||:|.|||||||::.|:.||:.|..||||.:..:| ::|||.:|:|||:.....|.|||.|
plant   209 EDFGIKYNMENGGPAPESITDKIYENTKTIKEYPIAEDLPRVDISTIGITSFEGPEGKFDVEVFD 273

  Fly   188 SVANYVRHMEEIFDFAKLKDFVS-GKATGKPLKMRIDAMNGVTGSYVREIFLNRLGATESSVVHT 251
            |..:||:.|:.||||..:|..:| .|.|     ...||::||.|:|...||:..|||.|||:::.
plant   274 SADDYVKLMKSIFDFESIKKLLSYPKFT-----FCYDALHGVAGAYAHRIFVEELGAPESSLLNC 333

  Fly   252 TPLPDFGGLHPDPNLTYAKDLV--------DTVAQGDYDIGAAFDGDGDRNMIIGSKAFFVTPSD 308
            .|..||||.||||||||||:||        |.......:.|||.|||.|||||:| |.|||||||
plant   334 VPKEDFGGGHPDPNLTYAKELVARMGLSKTDDAGGEPPEFGAAADGDADRNMILG-KRFFVTPSD 397

  Fly   309 SLAVI-AHYLEAIPYFQKNGVQGFARSMPTASAVDLVGRKLGKEVFEVPTGWKYFGNLMDAGRLC 372
            |:|:| |:.:.||||| .:|::|.||||||::|:|:|.:.||.:.||||||||:||||||||...
plant   398 SVAIIAANAVGAIPYF-SSGLKGVARSMPTSAALDVVAKNLGLKFFEVPTGWKFFGNLMDAGMCS 461

  Fly   373 LCGEESFGTGSNHIREKDGIWAVLAWISVMQHTGK----------GIEDILKQHWSVYGRNYFTR 427
            :||||||||||:||||||||||||||:|::.|..|          .:|||::|||:.|||:|:||
plant   462 VCGEESFGTGSDHIREKDGIWAVLAWLSILAHKNKETLDGNAKLVTVEDIVRQHWATYGRHYYTR 526

  Fly   428 YDYEECASDPCNEMVATMEKTITAPEFVGKSYSS-GGKTYKVKEADNFSYTDPVDKSVATKQGLR 491
            ||||...:....|::..:.|..::...|.|.... ..:...|..||.|.|.||||.||:..||:|
plant   527 YDYENVDATAAKELMGLLVKLQSSLPEVNKIIKGIHPEVANVASADEFEYKDPVDGSVSKHQGIR 591

  Fly   492 IVFEDGSRIVVRLSGTGSSGATVRLYIDSYEKE-NVLGQASV-MLKPLIDIALEISQLPKFTGRN 554
            .:||||||:|.|||||||.|||:||||:.|||: :.:|:.|. .|.||:|:||::|::.:||||:
plant   592 YLFEDGSRLVFRLSGTGSEGATIRLYIEQYEKDASKIGRDSQDALGPLVDVALKLSKMQEFTGRS 656

  Fly   555 APTVIT 560
            :|||||
plant   657 SPTVIT 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgm1	NP_524675.1	PLN02307	1..560	CDD:177942	313/589 (53%)
Pgm1	NP_524675.1	PGM1	6..560	CDD:100087	311/584 (53%)
PGM2	NP_001154465.1	PLN02307	77..662	CDD:177942	313/589 (53%)
PGM2	NP_001154465.1	PGM1	86..662	CDD:100087	311/582 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	182	1.000	Domainoid score	I1021
eggNOG	1	0.900	-	-		E1_COG0033
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	589	1.000	Inparanoid score	I231
OMA	1	1.010	-	-		QHG54024
OrthoDB	1	1.010	-	-		D555015at2759
OrthoFinder	1	1.000	-	-		FOG0001684
OrthoInspector	1	1.000	-	-		otm3086
orthoMCL	1	0.900	-	-		OOG6_100937
Panther	1	1.100	-	-	O	PTHR22573
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1241
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840