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Protein Alignment Pgm1 and PGM5

DIOPT Version :9

Sequence 1:	NP_524675.1	Gene:	Pgm1 / 44010	FlyBaseID:	FBgn0003076	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_068800.2	Gene:	PGM5 / 5239	HGNCID:	8908	Length:	567	Species:	Homo sapiens

Alignment Length:	566	Identity:	279/566 - (49%)
Similarity:	391/566 - (69%)	Gaps:	12/566 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LTVEIVATKPYEGQKP-GTSGLRKKVKVFT-QPNYTENFVQAILEA-NGAALAGSTLVVGGDGRF 64
            :.|..|.|.|||.|:| |..|||:...:|. |.||..||:|::|.: :.....|.|:|||.|||:
Human     6 IPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRY 70

  Fly    65 YCKEAAELIVRLSAANGVSKLLVGQNGILSTPAVSSLIRHNKALGGIVLTASHNPGGPENDFGIK 129
            :.:.|.|::|:::||||:.:|::||||||||||||.:||..||.|||:|||||.||||..:||:|
Human    71 FSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIRKIKAAGGIILTASHCPGGPGGEFGVK 135

  Fly   130 FNCENGGPAPDAFTNHIYKITTEIKEYKLVRNLQIDISKVGVTSFDIAG--KPFTVEVIDSVANY 192
            ||..|||||||..::.||:|:..|:||.:..:|:||:|::|...||:..  |||.||::|.|..|
Human   136 FNVANGGPAPDVVSDKIYQISKTIEEYAICPDLRIDLSRLGRQEFDLENKFKPFRVEIVDPVDIY 200

  Fly   193 VRHMEEIFDFAKLKDFVSGKATGKPLKMRIDAMNGVTGSYVREIFLNRLGATESSVVHTTPLPDF 257
            :..:..||||..:|..::|.:   .||:|||||:||.|.|||::..:.|||..:|.::..||.||
Human   201 LNLLRTIFDFHAIKGLLTGPS---QLKIRIDAMHGVMGPYVRKVLCDELGAPANSAINCVPLEDF 262

  Fly   258 GGLHPDPNLTYAKDLVDTVAQGDYDIGAAFDGDGDRNMIIGSKAFFVTPSDSLAVIAHYLEAIPY 322
            ||.|||||||||..|::.:..|:|..|||||.||||.||:|...|||:||||||:||..|..|||
Human   263 GGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPY 327

  Fly   323 FQKNGVQGFARSMPTASAVDLVGRKLGKEVFEVPTGWKYFGNLMDAGRLCLCGEESFGTGSNHIR 387
            |::.||:||.|||||:.|:|.|.:.:...|:|.|.||::|.||||:||..|||||||||||:|:|
Human   328 FRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTGSDHLR 392

  Fly   388 EKDGIWAVLAWISVMQHTGKGIEDILKQHWSVYGRNYFTRYDYEECASDPCNEMVATMEKTITAP 452
            ||||:||||.|:|::....:.:|:|::.||:.:||:|:.|:|||.........::..:|..:|..
Human   393 EKDGLWAVLVWLSIIAARKQSVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDK 457

  Fly   453 EFVGKSYSSGGKTYKVKEADNFSYTDPVDKSVATKQGLRIVFEDGSRIVVRLSGTGSSGATVRLY 517
            .|:|:.::.|...|.|.:.|:|.|.||||.:|..||||||:|.|.||::.|||.:....||:|||
Human   458 SFIGQQFAVGSHVYSVAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSSSGVRATLRLY 522

  Fly   518 IDSYEKENVLG---QASVMLKPLIDIALEISQLPKFTGRNAPTVIT 560
            .:|||:: ..|   :...:|.|||.|||:|||:.:.|||..|||||
Human   523 AESYERD-PSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT 567

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.