Protein Alignment Pgm1 and PGM1

DIOPT Version :9

• Sequence 1: NP_524675.1
• Gene: Pgm1 / 44010
• FlyBaseID: FBgn0003076
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001166289.1
• Gene: PGM1 / 5236
• HGNCID: 8905
• Length: 580
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 327/558 - (58%)
• Similarity: 415/558 - (74%)
• Gaps: 9/558 - (1%)

  Fly     9 ATKPYEGQKPGTSGLRKKVKVFTQ-PNYTENFVQAI-LEANGAALAGSTLVVGGDGRFYCKEAAE 71
            ||.||..|||||||||||...|.: |.|.|||:|:| ...:.....||:||||||||::.|.|.|
Human    26 ATAPYHDQKPGTSGLRKKTYYFEEKPCYLENFIQSIFFSIDLKDRQGSSLVVGGDGRYFNKSAIE 90

  Fly    72 LIVRLSAANGVSKLLVGQNGILSTPAVSSLIRHNKALGGIVLTASHNPGGPENDFGIKFNCENGG 136
            .||:::||||:.:|::||||||||||||.:||..||:|||:||||||||||..|||||||..|||
Human    91 TIVQMAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGG 155

  Fly   137 PAPDAFTNHIYKITTEIKEYKLVRNLQIDISKVGVTSFDIAG--KPFTVEVIDSVANYVRHMEEI 199
            |||:|.|:.|::|:..|:||.:..:|::|:..:|...||:..  ||||||::|||..|...:..|
Human   156 PAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSI 220

  Fly   200 FDFAKLKDFVSGKATGKPLKMRIDAMNGVTGSYVREIFLNRLGATESSVVHTTPLPDFGGLHPDP 264
            |||:.||:.:||.   ..||:|||||:||.|.||::|....|||..:|.|:..||.||||.||||
Human   221 FDFSALKELLSGP---NRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDP 282

  Fly   265 NLTYAKDLVDTVAQGDYDIGAAFDGDGDRNMIIGSKAFFVTPSDSLAVIAHYLEAIPYFQKNGVQ 329
            |||||.|||:|:..|::|.|||||||||||||:|...|||.||||:||||..:.:|||||:.||:
Human   283 NLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVR 347

  Fly   330 GFARSMPTASAVDLVGRKLGKEVFEVPTGWKYFGNLMDAGRLCLCGEESFGTGSNHIREKDGIWA 394
            ||||||||:.|:|.|.......::|.|||||:|||||||.:|.|||||||||||:|||||||:||
Human   348 GFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWA 412

  Fly   395 VLAWISVMQHTGKGIEDILKQHWSVYGRNYFTRYDYEECASDPCNEMVATMEKTITAPEFVGKSY 459
            ||||:|::....:.:|||||.||..||||:||||||||..::..|:|:..:|..:....||||.:
Human   413 VLAWLSILATRKQSVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQF 477

  Fly   460 SSGGKTYKVKEADNFSYTDPVDKSVATKQGLRIVFEDGSRIVVRLSGTGSSGATVRLYIDSYEKE 524
            |:..|.|.|::||||.|:||||.|::..||||::|.||||||.|||||||:|||:|||||||||:
Human   478 SANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGTGSAGATIRLYIDSYEKD 542

  Fly   525 --NVLGQASVMLKPLIDIALEISQLPKFTGRNAPTVIT 560
              .:.....|||.|||.|||::|||.:.|||.||||||
Human   543 VAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgm1	NP_524675.1	PLN02307	1..560	CDD:177942	325/556 (58%)
		PGM1	6..560	CDD:100087	325/556 (58%)
PGM1	NP_001166289.1	PGM1	24..580	CDD:100087	325/556 (58%)
		PLN02307	27..580	CDD:177942	324/555 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141578
Domainoid	1	1.000	189	1.000	Domainoid score	I3293
eggNOG	1	0.900	-	-		E1_COG0033
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1979
Inparanoid	1	1.050	668	1.000	Inparanoid score	I750
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54024
OrthoDB	1	1.010	-	-		D175278at33208
OrthoFinder	1	1.000	-	-		FOG0001684
OrthoInspector	1	1.000	-	-		otm40576
orthoMCL	1	0.900	-	-		OOG6_100937
Panther	1	1.100	-	-	LDO	PTHR22573
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R914
SonicParanoid	1	1.000	-	-		X1241
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800