Protein Alignment Hex-C and NGK1

DIOPT Version :10

• Sequence 1: NP_524674.1
• Gene: Hex-C / 44008
• FlyBaseID: FBgn0001187
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_013551.1
• Gene: NGK1 / 851167
• SGDID: S000004438
• Length: 433
• Species: Saccharomyces cerevisiae
• Alignment Length: 493
• Identity: 106/493 - (21%)
• Similarity: 175/493 - (35%)
• Gaps: 159/493 - (32%)

  Fly     2 LDAEVRELMQPF-----VLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEM 61
            |..|:..|:.|.     |:..:| :|:.||........|.:...|....:..|   :|
Yeast     7 LARELESLILPADSIVNVVDQFQ-EELLSRLQTNTISMLPQCLVPDKRSRWNP---ED------- 60

  Fly    62 GKYLALDLGGTNFRVLLVSLK----GHHDA------TVDSQ-----IYAVPKDLMVGPGVDLFDH 111
             |.|.:|.|||..:..::||.    .::||      .|||.     ||.:...|...
Yeast    61 -KILTIDFGGTRLKFAIISLPQIVIEYNDAFELTYNIVDSNFFNQIIYTICTRLAAN-------- 116

  Fly   112 IAGCLAKFVEKHDMKTAYLPLGFTFSFPCVQLGLKEGILVRWTKGFDCAG-VEGEDVGRMLHEAI 175
              |.:.|..|..:....::.:  |||||.    ..||.:|...|||.... ::|..|.:::..:.
Yeast   117 --GYIKKKNESSEASKFFVSV--TFSFPL----NPEGEVVAMGKGFVMTDTLQGSTVKQLIQSSF 173

  Fly   176 QRRGDADIA-------VVAILNDTTGTLMSCAHRNADCRVGVIVGTGCNAC------YVEDVENV 227
            .|....:|.       |..::||.....::......:..:.:|:|||.|||      |:...:.
Yeast   174 HRIISENIEEFFCTMNVCHVINDAIAVSLTSKFICENDSISLIIGTGTNACFEVPYGYLPPFKR- 237

  Fly   228 DLLRADF-----KKTK--RSVIVNAEWGAFGEG----------GQLDFVRTEYDREVDEKSLNRS 275
            |.||...     |:|.  :.|::|:|.|..|:.          |.:.:
Yeast   238 DALRETLPSSYNKETLNFKHVLINSEIGFIGKNVIALQPFDIHGAISY----------------- 285

  Fly   276 EQLFEKMTAGMYLGNLVRLVLLRALERKLIFKQSSRRPEFASVLQRNEEVFETRYISEIEDDSFP 340
            |...|.:|:|.:|...::.:||:                 .:::.:|                ||
Yeast   286 EMPLECVTSGKWLPLSLKNILLQ-----------------YNIIPKN----------------FP 317

  Fly   341 -EFASTRKIVKNLFGLEKASVEDCQTLRY-------ICE---CVAKRAATLVAIGVSG--LVNRT 392
             ||  ..::|..|       .|||....:       ||:   .:.||||..||..|..  ::...
Yeast   318 VEF--NGELVCQL-------AEDCTNAWFENEHYALICQIARLLIKRAAFYVAAIVQAIDIITGC 373

  Fly   393 SNRRVI-VGMDGS------VYRYHPKFDAYMRQTLQKL 423
            .|...| :|..||      .||...|:.:.:...||.|
Yeast   374 KNYNFIHIGYVGSFLHNSNFYREQIKYYSSIHIKLQFL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-C	NP_524674.1	ASKHA_NBD_HK_meta	14..448	CDD:466869	102/476 (21%)
NGK1	NP_013551.1	ASKHA_NBD_HK	19..423	CDD:466850	102/481 (21%)