Protein Alignment Hex-C and HXK1

DIOPT Version :10

• Sequence 1: NP_524674.1
• Gene: Hex-C / 44008
• FlyBaseID: FBgn0001187
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_116711.3
• Gene: HXK1 / 850614
• SGDID: S000001949
• Length: 485
• Species: Saccharomyces cerevisiae
• Alignment Length: 459
• Identity: 170/459 - (37%)
• Similarity: 251/459 - (54%)
• Gaps: 23/459 - (5%)

  Fly     5 EVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGKYLALDL 69
            |:.:|...|.:....:::|...|..|:.:||   |....|:...|.:|.:.|||.|.|.|||:||
Yeast    26 EIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGNYLAIDL 87

  Fly    70 GGTNFRVLLVSLKGHHDATVDSQIYAVPKDLMVGP-GVDLFDHIAGCLAKF-VEKHDMKTA-YLP 131
            ||||.||:||.|.|:|........|.:|.|:.... ..:|:..||..|..| ||:..:.|. .||
Yeast    88 GGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLP 152

  Fly   132 LGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDADIAVVAILNDTTGTL 196
            ||||||:|..|..:.||||.|||||||...|||.||..:|...|.:| :..|.:||::|||.|||
Yeast   153 LGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR-ELPIEIVALINDTVGTL 216

  Fly   197 MSCAHRNADCRVGVIVGTGCNACY---VEDVENVDLLRADFKKTKRSVIVNAEWGAFGEGGQLDF 258
            ::..:.:.:.::|||.|||.|..:   |.|:|.::...||...:...:.:|.|:|:| :...|..
Yeast   217 IASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSF-DNEHLVL 280

  Fly   259 VRTEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERKLIFKQSSRRPEFASVLQRNE 323
            .||:||..|||:|....:|.|||||:|.|||.|:|||||...|:.|:.|...     .|.| :..
Yeast   281 PRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQD-----LSKL-KQP 339

  Fly   324 EVFETRYISEIEDDSFPEFASTRKIVKNLFGLEKASVEDCQTLRYICECVAKRAATLVAIGVSGL 388
            .:.:|.|.:.||||.|.....|..|.:..||: |.::.:.:.:|.:||.:..|||.|...|::.:
Yeast   340 YIMDTSYPARIEDDPFENLEDTDDIFQKDFGV-KTTLPERKLIRRLCELIGTRAARLAVCGIAAI 403

  Fly   389 VNRTSNRRVIVGMDGSVYRYHPKFDAYMRQTLQKLV--KADKEWD---IMLSEDGSGRGAALVAA 448
            ..:...:...:..|||||..:|.|.....:.|:.:.  ..|...|   |:.:|||||.|||::||
Yeast   404 CQKRGYKTGHIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAA 468

  Fly   449 VASK 452
            ::.|
Yeast   469 LSEK 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-C	NP_524674.1	ASKHA_NBD_HK_meta	14..448	CDD:466869	164/444 (37%)
HXK1	NP_116711.3	ASKHA_NBD_HK1-2_fungi	38..471	CDD:466937	166/444 (37%)