Protein Alignment Hex-C and hk1

DIOPT Version :10

• Sequence 1: NP_524674.1
• Gene: Hex-C / 44008
• FlyBaseID: FBgn0001187
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_998417.1
• Gene: hk1 / 406791
• ZFINID: ZDB-GENE-040426-2848
• Length: 918
• Species: Danio rerio
• Alignment Length: 461
• Identity: 199/461 - (43%)
• Similarity: 292/461 - (63%)
• Gaps: 24/461 - (5%)

  Fly     3 DAEVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGKYLAL 67
            :.::.|.::.|.|:..|:.||..|...|:..||.:||...|.||..||||:..|.|.|.|.:|||
Zfish   467 ERQIAETLEEFRLTKDQLLEVKKRMRTEIQNGLSKSTQNTATVKMLPTYVRSTPDGSENGDFLAL 531

  Fly    68 DLGGTNFRVLLVSLKGHHDATVD--SQIYAVPKDLMVGPGVDLFDHIAGCLAKFVEKHDMKTAYL 130
            ||||||||||||.::.....||:  ::|||:|.::|.|.|.:|||||..|::.|::...||.|.|
Zfish   532 DLGGTNFRVLLVKIRSGKRRTVEMHNKIYAIPIEVMQGTGEELFDHIVYCISDFLDYMGMKNARL 596

  Fly   131 PLGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDADIAVVAILNDTTGT 195
            ||||||||||.|..|..|:||.|||||.....|||||..:|.|.|:||.:.|:.||||:|||.||
Zfish   597 PLGFTFSFPCRQTSLDAGLLVNWTKGFKATDCEGEDVVGLLREGIKRREEFDLDVVAIVNDTVGT 661

  Fly   196 LMSCAHRNADCRVGVIVGTGCNACYVEDVENVDLLRADFKKTKRSVIVNAEWGAFGEGGQLDFVR 260
            :|:||:....|.||:|.|||.||||:|::.|::.:..:    :..:.||.||||||:.|.||.:|
Zfish   662 MMTCAYEEPTCEVGLIAGTGSNACYMEEMRNIETVSGE----EGRMCVNMEWGAFGDNGCLDDIR 722

  Fly   261 TEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERKLIFKQSSRRPEFASVLQRNEEV 325
            |:||..||:.|||..:|.:|||.:|||||.:||.:|:...:|..:|     |.:.:..| :...:
Zfish   723 TKYDDAVDDLSLNAGKQKYEKMCSGMYLGEIVRNILIDLTKRGFLF-----RGQISETL-KTRGI 781

  Fly   326 FETRYISEIEDDSFPEFASTRKIVKNLFGLEKASVEDCQTLRYICECVAKRAATLVAIGVSGLVN 390
            |||:::|:||.|.. .....|.|:::| ||: ::.:|...::.:|..|::|||.|...|::.:|:
Zfish   782 FETKFLSQIESDRL-ALLQVRSILQHL-GLD-STCDDSIIVKEVCGAVSRRAAQLCGAGMAAVVD 843

  Fly   391 RTSNRR------VIVGMDGSVYRYHPKFDAYMRQTLQKLVKADK-EWDIMLSEDGSGRGAALVAA 448
            :....|      :.||:||::|:.||.|...|.||:::|  |.| ....:|||||||:||||:.|
Zfish   844 KIRENRGLDHLDITVGVDGTLYKLHPHFSRIMHQTVKEL--APKCNVTFLLSEDGSGKGAALITA 906

  Fly   449 VASKTK 454
            |..:.:
Zfish   907 VGCRLR 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-C	NP_524674.1	ASKHA_NBD_HK_meta	14..448	CDD:466869	195/442 (44%)
hk1	NP_998417.1	ASKHA_NBD_HK1_meta_rpt1	2..474	CDD:466974	1/6 (17%)
		ASKHA_NBD_HK1_meta_rpt2	478..911	CDD:466977	197/447 (44%)