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Protein Alignment Hex-C and Hk2

DIOPT Version :9

Sequence 1:	NP_524674.1	Gene:	Hex-C / 44008	FlyBaseID:	FBgn0001187	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_036867.1	Gene:	Hk2 / 25059	RGDID:	2797	Length:	917	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	206/465 - (44%)
Similarity:	293/465 - (63%)	Gaps:	44/465 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGKYLALDL 69
            :|.:.:....|||..:.|:..||..|:.:||..:|||.|.||..||:|:..|.|.|.|::|||||
  Rat    21 KVDQFLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDL 85

  Fly    70 GGTNFRVLLVSL--KGHHDATVDSQIYAVPKDLMVGPGVDLFDHIAGCLAKFVEKHDMKTAYLPL 132
            ||||||||.|.:  .|.....:::||||:|:|:|.|.|..||||||.|||.|::|..:|...|||
  Rat    86 GGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKLPL 150

  Fly   133 GFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDADIAVVAILNDTTGTLM 197
            ||||||||.|..|.|..||.|||||..:||||.||..::.:|||||||.||.:||::|||.||:|
  Rat   151 GFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMM 215

  Fly   198 SCAHRNADCRVGVIVGTGCNACYVEDVENVDLLRADFKKTKRSVIVNAEWGAFGEGGQLDFVRTE 262
            :|.:.:.:|.:|:|||||.||||:|::.::|::..|    :..:.:|.||||||:.|.|:.:|||
  Rat   216 TCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGD----EGRMCINMEWGAFGDDGTLNDIRTE 276

  Fly   263 YDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERKLIFKQSSRRPEFASVLQRNEEVFE 327
            :|||:|..|||..:||||||.:|||:|.||||:|::..:.:|:| |....||..:.     ..||
  Rat   277 FDREIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKAELLF-QGKLSPELLTT-----GSFE 335

  Fly   328 TRYISEIEDDSFPEFASTRKIVKNLFGLEKA-----------SVEDCQTLRYICECVAKRAATLV 381
            |:.:|:||:|.              .|:|||           ..|||.....||:.|:.|:|:|.
  Rat   336 TKDVSDIEEDK--------------DGIEKAYQILMRLGLNPLQEDCVATHRICQIVSTRSASLC 386

  Fly   382 AIGVSGLV-----NRTSNR-RVIVGMDGSVYRYHPKFDAYMRQTLQKLVKADKEWDIMLSEDGSG 440
            |..::.::     |:...| |..:|:|||||:.||.|...:.:.:::|| .|.:...:.||||||
  Rat   387 AATLAAVLWRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLV-PDCDVRFLRSEDGSG 450

  Fly   441 RGAALVAAVA 450
            :|||:|.|||
  Rat   451 KGAAMVTAVA 460

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.