Protein Alignment Hex-C and gck

DIOPT Version :10

• Sequence 1: NP_524674.1
• Gene: Hex-C / 44008
• FlyBaseID: FBgn0001187
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_012813876.1
• Gene: gck / 100124905
• XenbaseID: XB-GENE-981992
• Length: 465
• Species: Xenopus tropicalis
• Alignment Length: 474
• Identity: 204/474 - (43%)
• Similarity: 301/474 - (63%)
• Gaps: 38/474 - (8%)

  Fly     1 MLD-------AEVRELMQPFVLSDYQVQE-----VYSRFCLEVARGLKRSTHPQANVKCFPTYVQ 53
            |||       .:::::.|  :||::.:||     :..|...|:.|||...|:.:|:||..||||:
 Frog     1 MLDIKNKMEATQIQKVDQ--ILSEFHLQEEDLHVLMCRMQAEMERGLHLETNEEASVKMLPTYVR 63

  Fly    54 DLPTGDEMGKYLALDLGGTNFRVLLV----SLKGHHDATVDSQIYAVPKDLMVGPGVDLFDHIAG 114
            ..|.|.|:|.:||||||||||||:||    .|:|........::|::|:|.|.|....|||:||.
 Frog    64 STPDGSEVGDFLALDLGGTNFRVMLVKVGEDLEGQWKVETKHKMYSIPEDAMTGTAEMLFDYIAE 128

  Fly   115 CLAKFVEKHDMKTAYLPLGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRG 179
            |::.::::.:||...||||||||||.....:.:|||:.|||||..:|.||.:|..:|.:||:|||
 Frog   129 CISDYLDQQNMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193

  Fly   180 DADIAVVAILNDTTGTLMSCAHRNADCRVGVIVGTGCNACYVEDVENVDLLRADFKKTKRSVIVN 244
            |.::.|||::|||..|::||.:.:..|.||:||||||||||:|::.||:|:..:    :..:.||
 Frog   194 DFEMDVVAMVNDTVATMISCYYEDHHCEVGLIVGTGCNACYMEEMSNVELVEGE----EGRMCVN 254

  Fly   245 AEWGAFGEGGQLDFVRTEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERKLIFKQS 309
            .||||||:.|:|:..|.||||.|||.|||..:||:|||..|.|:|.||||||::.:...|||...
 Frog   255 TEWGAFGDTGELEDFRLEYDRVVDEASLNPGQQLYEKMIGGKYMGELVRLVLIKMVNENLIFGGE 319

  Fly   310 SRRPEFASVLQRNEEVFETRYISEIEDDSFPEFASTRKIVKNLFGLEKASVEDCQTLRYICECVA 374
            |      |...:....|:|:::|:||.|: .:|..|..|::.| |:: |::.||..:|..||.|:
 Frog   320 S------SEKLKTRGAFDTQFVSQIEADT-SDFKQTLNILRTL-GVQ-ATIGDCHAVRLACESVS 375

  Fly   375 KRAATLVAIGVSGLVNR--TSNR----RVIVGMDGSVYRYHPKFDAYMRQTLQKLVKADKEWDIM 433
            .|||.:.:.|::.::||  .|.|    |:.||:|||||:.||.|......|:.||. :..|...:
 Frog   376 TRAAVMCSSGLAAILNRMHQSRRGELSRITVGVDGSVYKLHPSFKDKFHATVHKLT-SGCEITFI 439

  Fly   434 LSEDGSGRGAALVAAVASK 452
            .||:||||||||::|||.|
 Frog   440 QSEEGSGRGAALISAVAYK 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-C	NP_524674.1	ASKHA_NBD_HK_meta	14..448	CDD:466869	196/448 (44%)
gck	XP_012813876.1	ASKHA_NBD_HK4_meta	15..458	CDD:466942	200/458 (44%)