DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sras and rce1b

DIOPT Version :9

Sequence 1:	NP_524673.3	Gene:	Sras / 44002	FlyBaseID:	FBgn0029121	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_017208487.1	Gene:	rce1b / 566908	ZFINID:	ZDB-GENE-091204-277	Length:	306	Species:	Danio rerio

Alignment Length:	275	Identity:	124/275 - (45%)
Similarity:	171/275 - (62%)	Gaps:	13/275 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SVSCCFVLAVLYVGSLYIWSTKHNRDHPTTVKRRFASVSMVMLAAPFFVYFFS-SPELLSRVPFP 93
            |||||.:||.|||||||:|.....||||.|:||||.||..|...||..|..:: |.:|....|..
Zfish    18 SVSCCLLLACLYVGSLYVWKGSLPRDHPNTIKRRFTSVLCVSAVAPLVVLAWTHSMKLRPSPPLW 82

  Fly    94 KLLGLRLEGLWQAVVIPYSLTVLLFLGPIFVNMQNESVRSYF--------DLDYWRGSFGSIIWV 150
            .|||:||||...|.|:|.:||::|||||: ..:..||.|..|        |...|......:.|:
Zfish    83 ALLGIRLEGFVPAAVLPLTLTMVLFLGPL-TQLAVESPRGLFHDVKAGLTDCQSWSKQVKDLKWL 146

  Fly   151 RNHVIAPLSEEFVFRACMMPLILQSFSPLVAVFITPLFFGVAHLHHIAERLSLGVELSTALLI-G 214
            ||||:|||:||||||||::|:::....|..|:||:||||||||.|||.|:|..|.:....:|| .
Zfish   147 RNHVVAPLTEEFVFRACIIPMLVPCTGPTSAIFISPLFFGVAHFHHIIEQLRFGQDTVFDILICA 211

  Fly   215 LFQFIYTTLFGFYSAFLFARTGHVMAPILVHAFCNHMGLPDLQDLWQQDLWRRVVAIILYLAGFV 279
            .|||.||::||.|:||:|.||||::.|:|.|:|||.||.|.:..:.:..  ::.:.::.|..|.:
Zfish   212 AFQFTYTSVFGVYTAFIFIRTGHLVGPVLCHSFCNRMGFPAIGSVLEHP--QKSLILLFYQLGVL 274

  Fly   280 GWMFLVPLATDPSIY 294
            .:..|:...|||:.|
Zfish   275 LFFILLFPFTDPTFY 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sras	NP_524673.3	YdiL	<72..253	CDD:224185	88/190 (46%)
Sras	NP_524673.3	Abi	147..249	CDD:280650	56/102 (55%)
rce1b	XP_017208487.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581796
Domainoid	1	1.000	133	1.000	Domainoid score	I5013
eggNOG	1	0.900	-	-		E1_KOG4130
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3386
OMA	1	1.010	-	-		QHG58442
OrthoDB	1	1.010	-	-		D1607650at2759
OrthoFinder	1	1.000	-	-		FOG0003941
OrthoInspector	1	1.000	-	-		otm25611
orthoMCL	1	0.900	-	-		OOG6_103186
Panther	1	1.100	-	-	O	PTHR13046
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3240
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770