DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaG and sucla2

DIOPT Version :9

Sequence 1:	NP_001286941.1	Gene:	ScsbetaG / 44001	FlyBaseID:	FBgn0029118	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_998191.1	Gene:	sucla2 / 406299	ZFINID:	ZDB-GENE-040426-1963	Length:	466	Species:	Danio rerio

Alignment Length:	393	Identity:	184/393 - (46%)
Similarity:	252/393 - (64%)	Gaps:	3/393 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGTFDNGF 85
            |.|:|.|:.|..||::.|:::....|.:.........|.....:.|:|||:||||||||||:.|.
Zfish    54 RKLSLHEYMSIGLLKEAGISVPAGMVASTPDEAYTAAKQIGSKDLVIKAQVLAGGRGKGTFEGGL 118

  Fly    86 KGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDREHNGP 150
            ||||.|..:..|...::.:|||.:|.||||.::|.:.|:|.|.......||.|..|.::|.:.||
Zfish   119 KGGVRIVYSPEEARDISSKMIGKKLFTKQTGEAGRICNQVFVCERRYPRREYYFAITMERSYQGP 183

  Fly   151 VLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEIQKLYT 215
            |||.|..||::||.||.|.|:.|...|:||.:.|.....::||:.:.|....:...||.:.|||.
Zfish   184 VLIGSSQGGVNIEDVAAENPDAIVKEPIDIVEGIKMDQAIKVAEKMGFPPALINEAAENMLKLYD 248

  Fly   216 LFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSM-DVTEEESDPREVEAAKYN 279
            :|...||..:||||:.|...|.|:.:|||:|||.||.:|||.:|.| |.::|  |.|:.:|||.:
Zfish   249 VFIKYDASMVEINPMVEDSSGIVMCMDAKINFDSNAAYRQKKVFDMRDWSQE--DARDRQAAKAD 311

  Fly   280 LNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPKVKGI 344
            |||:.:||.||||||||||||||||||||:||.||||||||||....||.:||:::|:|.||:.|
Zfish   312 LNYIGLDGTIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATAQQVTEAFKLITSDKKVQAI 376

  Fly   345 LVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLPIQTASDLDDAAH 409
            |||:||||:.|..||.||:.|...|.|.:|:||||:||.|:.|:.::..|.|.|....|||:||.
Zfish   377 LVNIFGGIMRCDVIAQGIIMAVTDLDLKIPIVVRLQGTRVDDAKALIAASPLKILACDDLDEAAK 441

  Fly   410 KAV 412
            ..|
Zfish   442 MVV 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaG	NP_001286941.1	sucC	24..416	CDD:234813	182/390 (47%)
		ATP-grasp_4	24..232	CDD:302634	80/207 (39%)
		Ligase_CoA	292..412	CDD:278948	70/119 (59%)
sucla2	NP_998191.1	sucC	58..448	CDD:234813	182/389 (47%)
		ATP-grasp_2	58..265	CDD:285620	80/206 (39%)
		Ligase_CoA	324..444	CDD:278948	70/119 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60702
OrthoDB	1	1.010	-	-		D342254at33208
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100409
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.730