DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaG and Suclg2

DIOPT Version :9

Sequence 1:	NP_001286941.1	Gene:	ScsbetaG / 44001	FlyBaseID:	FBgn0029118	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001094220.1	Gene:	Suclg2 / 362404	RGDID:	1305008	Length:	434	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	238/400 - (59%)
Similarity:	303/400 - (75%)	Gaps:	1/400 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 HKVPVRNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGT 80
            |..|.|.|||.|:|||.|:.::||.:|:|.|.:.:|...|..|.....|.|:||||||||||||.
  Rat    33 HLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVASTAKEAQEAAKRLNAKEIVLKAQILAGGRGKGV 97

  Fly    81 FDNGFKGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDR 145
            ||:|.|||||:|.:...|..|.|||||..|.||||||.|:.|||||||.:::|:|||||.||:||
  Rat    98 FDSGLKGGVHLTKDPKVVGQLAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDR 162

  Fly   146 EHNGPVLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEI 210
            .||||||:.||.||:|||.||..:||.|....:||.:.|.:|....:|:.|.|.|....:.|::|
  Rat   163 SHNGPVLVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQI 227

  Fly   211 QKLYTLFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSMDVTEEESDPREVEA 275
            :|||.||..:||.|:|:||..||.:|:|:..|||:||||||:|||||||:|| .:.|::|.|.||
  Rat   228 KKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMD-DKSENEPIENEA 291

  Fly   276 AKYNLNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPK 340
            |:|:|.|:.:||||.|.||||||||||.|||.||||:||||||:||||:|.||.:||::||:|||
  Rat   292 ARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKESQVYQAFKLLTSDPK 356

  Fly   341 VKGILVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLPIQTASDLD 405
            |:.||||:||||||||.|||||..|.::|:|.||||||||||||.:|:.|||:|||||.:|.||:
  Rat   357 VEAILVNIFGGIVNCAIIANGITKACQELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLE 421

  Fly   406 DAAHKAVAAL 415
            |||.||||::
  Rat   422 DAAKKAVASV 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaG	NP_001286941.1	sucC	24..416	CDD:234813	234/391 (60%)
		ATP-grasp_4	24..232	CDD:302634	109/207 (53%)
		Ligase_CoA	292..412	CDD:278948	86/119 (72%)
Suclg2	NP_001094220.1	sucC	41..422	CDD:234813	227/381 (60%)
		ATP-grasp_2	41..249	CDD:285620	109/207 (53%)
		Ligase_CoA	308..422	CDD:278948	82/113 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337531
Domainoid	1	1.000	203	1.000	Domainoid score	I2886
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2854
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1522
OMA	1	1.010	-	-		QHG60702
OrthoDB	1	1.010	-	-		D342254at33208
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	1	1.000	-	-		oto98682
orthoMCL	1	0.900	-	-		OOG6_100409
Panther	1	1.100	-	-	LDO	PTHR11815
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3948
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810