DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaG and Sucla2

DIOPT Version :9

Sequence 1:	NP_001286941.1	Gene:	ScsbetaG / 44001	FlyBaseID:	FBgn0029118	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001101857.2	Gene:	Sucla2 / 361071	RGDID:	1309397	Length:	465	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	189/392 - (48%)
Similarity:	262/392 - (66%)	Gaps:	1/392 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGTFDNGF 85
            |:|:|.|:.|.:|||:.||::.:..|..:|.....:.|.....:.|:|||:||||||||||.:|.
  Rat    53 RSLSLHEYLSMELLQEAGVSVPKGFVAKSSDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFTSGL 117

  Fly    86 KGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDREHNGP 150
            ||||.|..:..|..:::.||||.:||||||...|.:.|:|:|.......||.|..|.::|...||
  Rat   118 KGGVKIVFSPEEAKAVSSQMIGQKLITKQTGAKGRICNQVLVCERKYPRREYYFAITMERSFQGP 182

  Fly   151 VLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEIQKLYT 215
            |||.|..||::||.||.|.||.|...|:||.:.:.:...:.:||.:.|..:.|...||.:.|||.
  Rat   183 VLIGSSQGGVNIEDVAAENPEAIVKEPVDIIEGVKKEQAVTLAKKMGFPSNIVDSAAENMIKLYN 247

  Fly   216 LFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSMDVTEEESDPREVEAAKYNL 280
            ||...||..:||||:.|...|:|:.:|||:|||.|:.:|||.||::....:| |.|:.:||..::
  Rat   248 LFLKYDATMVEINPMVEDADGKVLCMDAKINFDSNSAYRQKKIFALQDWSQE-DERDKDAADADI 311

  Fly   281 NYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPKVKGIL 345
            ||:.:|||||||||||||||||||||||:||.||||||||||....||.:||:::|:|.:|:.||
  Rat   312 NYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKRVQAIL 376

  Fly   346 VNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLPIQTASDLDDAAHK 410
            ||:||||:.|..||.|||.|.|.|::.:|:||||:||.|:.|:.::.:|||.|....|||:||..
  Rat   377 VNIFGGIMRCDIIAQGIVMAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKM 441

  Fly   411 AV 412
            .|
  Rat   442 VV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaG	NP_001286941.1	sucC	24..416	CDD:234813	187/389 (48%)
		ATP-grasp_4	24..232	CDD:302634	87/207 (42%)
		Ligase_CoA	292..412	CDD:278948	71/119 (60%)
Sucla2	NP_001101857.2	sucC	57..447	CDD:234813	187/388 (48%)
		ATP-grasp_2	57..264	CDD:285620	87/206 (42%)
		Ligase_CoA	323..443	CDD:278948	71/119 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60702
OrthoDB	1	1.010	-	-		D342254at33208
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100409
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730