DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaG and suclg2

DIOPT Version :9

Sequence 1:	NP_001286941.1	Gene:	ScsbetaG / 44001	FlyBaseID:	FBgn0029118	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_021328137.1	Gene:	suclg2 / 317746	ZFINID:	ZDB-GENE-030114-3	Length:	453	Species:	Danio rerio

Alignment Length:	397	Identity:	237/397 - (59%)
Similarity:	299/397 - (75%)	Gaps:	1/397 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PVRNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGTFDN 83
            |.|.|||.|:|||.|:|..|||:|:|.|.:.:....|..|..:..|.|:||||||||||||.|::
Zfish    55 PRRWLNLQEYQSKKLMQDSGVAVQRFFVADTASEALEAAKRLKAKEIVLKAQILAGGRGKGVFNS 119

  Fly    84 GFKGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDREHN 148
            |.|||||:|.:.:.|..|..:|:|..|.||||||.|:.|..||||.:::|:||||..||:||..|
Zfish   120 GLKGGVHLTKDPAVVGELASKMLGYNLTTKQTPKEGVEVKTVMVAEALDISRETYFAILMDRSCN 184

  Fly   149 GPVLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEIQKL 213
            |||::.||.||||||.||..|||.|....:||.:.:.:...|.:|..|.|||...::.|::|::|
Zfish   185 GPVMVGSPQGGMDIEEVAAATPELIFKEVIDIFEGVRDDQALRMAANLGFKGPLERQAADQIKRL 249

  Fly   214 YTLFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSMDVTEEESDPREVEAAKY 278
            |.||..|||.|:|:|||.||.:|:|:..|||:||||||:||||.:||||.| .||||.|.|||||
Zfish   250 YDLFLKVDATQVEVNPLGETPEGQVVCFDAKINFDDNAEFRQKAVFSMDDT-AESDPIETEAAKY 313

  Fly   279 NLNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPKVKG 343
            :|.|:.|||||.|.||||||||||.|||.|:||:||||||:||||:|:||..||::|||||||:.
Zfish   314 DLKYIGMDGNIACFVNGAGLAMATCDIIDLHGGKPANFLDLGGGVKENQVYAAFKLLTADPKVEA 378

  Fly   344 ILVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLPIQTASDLDDAA 408
            ||||:||||||||.|||||..|.::|:|.||||||||||||::|:.||..|||||.:|:||||||
Zfish   379 ILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVHEAKRILSESGLPITSATDLDDAA 443

  Fly   409 HKAVAAL 415
            .|||||:
Zfish   444 RKAVAAI 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaG	NP_001286941.1	sucC	24..416	CDD:234813	234/392 (60%)
		ATP-grasp_4	24..232	CDD:302634	104/207 (50%)
		Ligase_CoA	292..412	CDD:278948	86/119 (72%)
suclg2	XP_021328137.1	sucC	60..441	CDD:234813	225/381 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576707
Domainoid	1	1.000	202	1.000	Domainoid score	I2941
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2854
Inparanoid	1	1.050	462	1.000	Inparanoid score	I1528
OMA	1	1.010	-	-		QHG60702
OrthoDB	1	1.010	-	-		D342254at33208
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	1	1.000	-	-		otm24656
orthoMCL	1	0.900	-	-		OOG6_100409
Panther	1	1.100	-	-	LDO	PTHR11815
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2824
SonicParanoid	1	1.000	-	-		X3948
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800