DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaG and Suclg2

DIOPT Version :9

Sequence 1:	NP_001286941.1	Gene:	ScsbetaG / 44001	FlyBaseID:	FBgn0029118	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_035637.2	Gene:	Suclg2 / 20917	MGIID:	1306824	Length:	433	Species:	Mus musculus

Alignment Length:	400	Identity:	237/400 - (59%)
Similarity:	302/400 - (75%)	Gaps:	1/400 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 HKVPVRNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGT 80
            |..|.|.|||.|:|||.|:.::||.:|:|.|.|.:|...|..|.....|.|:||||||||||||.
Mouse    32 HLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVANTAKEALEAAKRLNAKEIVLKAQILAGGRGKGV 96

  Fly    81 FDNGFKGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDR 145
            |::|.|||||:|.:...|..|.|||||..|.||||||.|:.|||||||.:::|:|||||.||:||
Mouse    97 FNSGLKGGVHLTKDPKVVGELAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDR 161

  Fly   146 EHNGPVLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEI 210
            .|||||::.||.||:|||.||..:||.|....:||.:.|.:|....:|:.|.|.|....:.|::|
Mouse   162 SHNGPVIVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQI 226

  Fly   211 QKLYTLFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSMDVTEEESDPREVEA 275
            .|||.||..:||.|:|:||..||.:|:|:..|||:||||||:|||||||:|| .:.|::|.|.||
Mouse   227 TKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMD-DKSENEPIENEA 290

  Fly   276 AKYNLNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPK 340
            |:|:|.|:.:||||.|.||||||||||.|||.||||:||||||:||||:|.||.:||::||:|||
Mouse   291 ARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPK 355

  Fly   341 VKGILVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLPIQTASDLD 405
            |:.||||:||||||||.|||||..|.::|:|.||||||||||||.:|:.|||:|||||.:|.||:
Mouse   356 VEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLE 420

  Fly   406 DAAHKAVAAL 415
            |||.||||::
Mouse   421 DAAKKAVASV 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaG	NP_001286941.1	sucC	24..416	CDD:234813	233/391 (60%)
		ATP-grasp_4	24..232	CDD:302634	108/207 (52%)
		Ligase_CoA	292..412	CDD:278948	86/119 (72%)
Suclg2	NP_035637.2	sucC	40..421	CDD:234813	226/381 (59%)
		ATP-grasp_2	40..248	CDD:285620	108/207 (52%)
		Ligase_CoA	307..421	CDD:278948	82/113 (73%)
		Substrate binding, shared with subunit alpha. /evidence=ECO:0000255\|HAMAP-Rule:MF_03221	366..368		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833992
Domainoid	1	1.000	212	1.000	Domainoid score	I2785
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2854
Inparanoid	1	1.050	466	1.000	Inparanoid score	I1523
Isobase	1	0.950	-	0	Normalized mean entropy	S484
OMA	1	1.010	-	-		QHG60702
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	1	1.000	-	-		oto95191
orthoMCL	1	0.900	-	-		OOG6_100409
Panther	1	1.100	-	-	LDO	PTHR11815
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2824
SonicParanoid	1	1.000	-	-		X3948
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740