DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaG and sucg-1

DIOPT Version :9

Sequence 1:	NP_001286941.1	Gene:	ScsbetaG / 44001	FlyBaseID:	FBgn0029118	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_501266.1	Gene:	sucg-1 / 177555	WormBaseID:	WBGene00016844	Length:	415	Species:	Caenorhabditis elegans

Alignment Length:	414	Identity:	246/414 - (59%)
Similarity:	312/414 - (75%)	Gaps:	3/414 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLKAVTTARHIVHKVPVRNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVK 68
            :|:|.......:.|...|.|||.|||||::|:|:|.::|.|.|.:|.|...|...:|...|||||
Worm     1 MLRAAGNLSKSMMKSQRRFLNLQEFQSKEILEKHGCSVQNFVVASNRKEAEEKWMSFGDHEYVVK 65

  Fly    69 AQILAGGRGKGTFDNGFK--GGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSI 131
            |||||||||||.|.||.|  |||.||..|...|....:|||.||:||||...|:.|:|||:|..:
Worm    66 AQILAGGRGKGKFINGTKGIGGVFITKEKDAALEAIDEMIGKRLVTKQTTSEGVRVDKVMIAEGV 130

  Fly   132 NITRETYLCILLDREHNGPVLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFL 196
            :|.|||||.:|:|||.||||::|||.||||||||||:|||:|...|:||...:.|...|::||.|
Worm   131 DIKRETYLAVLMDRESNGPVVVASPDGGMDIEAVAEKTPERIFKTPIDIQMGMTEGQSLKIAKDL 195

  Fly   197 EFKGDSVKRCAEEIQKLYTLFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSM 261
            :|:|..:...|:||::||.||.||||.|:|||||.||..|.|..||||:||||:|.:|||:||:.
Worm   196 QFEGKLIGVAAQEIKRLYDLFIAVDATQVEINPLVETADGRVFCVDAKMNFDDSAAYRQKEIFAY 260

  Fly   262 DVTEEESDPREVEAAKYNLNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVRED 326
            : |.||.|||||:|.::||||:.|||||.||||||||||||||:|||:||||||||||||.|.||
Worm   261 E-TFEEHDPREVDAHQFNLNYIGMDGNIACLVNGAGLAMATMDLIKLHGGEPANFLDVGGAVTED 324

  Fly   327 QVAKAFEILTADPKVKGILVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREIL 391
            .|..|..|:|:||:||.:|:|:|||||||||||||:|:|..|:.||||:|||||||||:.|::|:
Worm   325 AVFNAVRIITSDPRVKCVLINIFGGIVNCATIANGVVSAVNKIGLNVPMVVRLEGTNVDAAKQIM 389

  Fly   392 KNSGLPIQTASDLDDAAHKAVAAL 415
            |.|||.|.||::||:||.|||::|
Worm   390 KKSGLKILTANNLDEAAAKAVSSL 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaG	NP_001286941.1	sucC	24..416	CDD:234813	241/394 (61%)
		ATP-grasp_4	24..232	CDD:302634	117/209 (56%)
		Ligase_CoA	292..412	CDD:278948	84/119 (71%)
sucg-1	NP_501266.1	sucC	21..410	CDD:234813	238/389 (61%)
		ATP-grasp_2	21..231	CDD:285620	117/209 (56%)
		Ligase_CoA	290..410	CDD:278948	84/119 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157874
Domainoid	1	1.000	222	1.000	Domainoid score	I1477
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2854
Inparanoid	1	1.050	473	1.000	Inparanoid score	I827
Isobase	1	0.950	-	0	Normalized mean entropy	S484
OMA	1	1.010	-	-		QHG60702
OrthoDB	1	1.010	-	-		D342254at33208
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	1	1.000	-	-		oto17854
orthoMCL	1	0.900	-	-		OOG6_100409
Panther	1	1.100	-	-	LDO	PTHR11815
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2824
SonicParanoid	1	1.000	-	-		X3948
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750