Protein Alignment Spt6 and GTB1

DIOPT Version :9

• Sequence 1: NP_001284936.1
• Gene: Spt6 / 44000
• FlyBaseID: FBgn0028982
• Length: 1831
• Species: Drosophila melanogaster
• Sequence 2: NP_001321759.1
• Gene: GTB1 / 842855
• AraportID: AT1G65440
• Length: 1647
• Species: Arabidopsis thaliana
• Alignment Length: 1915
• Identity: 475/1915 - (24%)
• Similarity: 833/1915 - (43%)
• Gaps: 408/1915 - (21%)

  Fly    11 ESEEEEELDVNERKRLKKLKAAVSDSSEEEEDDEERLREELKDLI----DDNPIEEDDGSGYDSD 71
            :.||:.||:.::.:.:....|...::.:||:||:.....|....|    |:...||:|....|||
plant     8 DDEEDHELEDDDGEPVHGDPAEHDENDDEEDDDDVGNEYENDGFIVNDEDEEEEEEEDEERKDSD 72

  Fly    72 GVGSGKKRKKHEDDDLDDRLEDDDYDLIEENLGVKVERRKRFKRLRRIHDNESDGEEQHVDEGL- 135
            .....||:|:.:.   |:.|::|||.|:::| .||.::| ::|||::....:.:|:.:..|:..
plant    73 EERQKKKKKRKKK---DEGLDEDDYLLLQDN-NVKFKKR-QYKRLKKAQREQGNGQGESSDDEFD 132

  Fly   136 --------VREQIAEQLFDEND-----ESIGHRSERSHREADDYDDVDTESDADDFIV---DDNG 184
                    ..::|.::|||:.|     :.:|...:....|    |.|.:|.:..||||   |::|
plant   133 SRGGTRRSAEDKIKDRLFDDVDVDDPPDDVGDEEDLVVEE----DVVGSEDEMADFIVDEDDEHG 193

  Fly   185 RPIA--EKKKKRRPIFTDASLQEGQDIFGVDFDYDDFSKYEEDDYEDDSEGDEYDEDLGVGDDTR 247
            .|..  .||||.|......::::..:|||   |.|:.                          ..
plant   194 PPKRGNSKKKKYRQGSDITAMRDANEIFG---DVDEL--------------------------LT 229

  Fly   248 VKKKKALKKKVVKKTIFDIYEPSELKRGHFTDMDNEIRKTDIPERMQLREVPVTPVPEGSDELDL 312
            ::||.....:.:::.:.|.:||:.|...:.|..|:|||:.|||||||:.|......|.....::.
plant   230 IRKKGLASNQRMERRLEDEFEPTVLSEKYMTGNDDEIRQLDIPERMQISEESTGSPPVDEISIEE 294

  Fly   313 EAEWIYKYAFCKHTVSEQEKPESREKMRKPPTT-------VNK--IKQTLEFIRNQQLEVPFIAF 368
            |:.|||              .:...::|:...|       |||  |.:.||....|:||:||||.
plant   295 ESNWIY--------------AQLASQLRESDGTFDGRGFSVNKDDIAKFLELHHVQKLEIPFIAM 345

  Fly   369 YRKEYVKPELNIDD-----------------LWKVYYYDGIWCQLNERKRKLKVLFEKMRQFQLD 416
            ||||..:..|:..|                 .|.::..|..|..|.:||..|...:.|..:
plant   346 YRKEQCRSLLDTGDFDGANQGKKPETKWHKVFWMIHDLDKKWLLLRKRKMALHGYYTKRYE---- 406

  Fly   417 TLCADTDQPVPDDVRL-----ILDSDFERLADVQSMEELKDVHMYFLLNYSHELPRMQAEQRRKA 476
                :..:.|.|:.||     :.:|..:.|...::..|:.||...|.|::
plant   407 ----EESRRVYDETRLNLNQYLFESVIKSLKVAETEREVDDVDSKFNLHF--------------- 452

  Fly   477 IQERREAKARRQAAAAENGDDAAEAIVVPEPEDDDDPELIDYQLKQASNSSPYAVFRKAGICGFA 541
                         ...|.|.|                   :.|.|:....|.|::..|||:...|
plant   453 -------------PPGEIGVD-------------------EGQYKRPKRKSQYSICSKAGLWEVA 485

  Fly   542 KHFGLTPEQYAENLRDNYQRNEITQESIGPTELAKQYLSPRFMTTDEVIHAAKYVVARQLAQEPL 606
            ..||.:.||....|......:|:......|.|:||.::...|..:..|:..|:::.|.:::.||.
plant   486 NKFGYSAEQLGLALSLEKLVDELEDAKETPEEMAKNFVCAMFENSLAVLKGARHMAAVEISCEPS 550

  Fly   607 LRKTMREVYFDRARINIRPTKNGMVLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLE 671
            ::|.:|.:|.:.|.::..||.:|..:||.......:|::.:||:|...|.|::.:...||||||:
plant   551 VKKYVRGIYMENAVVSTSPTADGNTVIDSFHQFSGIKWLREKPLSKFEGAQWLLIQKGEEEKLLQ 615

  Fly   672 ITFLEEFEGNACANGTPGDY----VEESKALYQLDQFAKHVQEWNKLRAECVQLALQKWVIPDLI 732
            :||           ..|.:|    :.:....|.....:|:.|.||:.|...::.||..:::|.:.
plant   616 VTF-----------KLPENYMNRLISDCNEHYLSVGVSKYAQLWNEQRKLILEDALHAFLLPSME 669

  Fly   733 KELRSTLHEEAQQFVLRSCTGKLYKWLKVAPYKPQLPPDFGYEEWSTLRGIRVLGLAYDPDHSVA 797
            ||.||.|...|:..:|......|:..:...||:.: ..|...:|.:   ..||:...:.|.....
plant   670 KEARSLLTSRAKSRLLSEYGQALWNKVSAGPYQKK-EMDINLDEEA---APRVMACCWGPGKPPN 730

  Fly   798 AFCAVTTVEGDISDYLRLPNILKRKNSYNLEEKAQKLADLRKLSDFIKMKKPHIVVIGAESRDAQ 862
            .|..:.: .|::.|.|...::..|  |.|:.::.:|.:|..::..|:...:||:|.:||.:....
plant   731 TFVMLDS-SGEVLDVLYAGSLTSR--SQNVNDQQRKKSDQDRVLKFMMDHQPHVVALGAVNLSCT 792

  Fly   863 NIQADIKEILHEL------ETSEQFPPIEVEIIDNELAKIYANSKKGESDFKEYPPLLKQAASLA 921
            .::.||.|::.::      :.......:.:..:|..|.::|.||:.......:....:::|.:|.
plant   793 RLKDDIYEVIFQMVEEKPRDVGHGMDDLSIVYVDESLPRLYENSRISGEQLPQQSGNVRRAVALG 857

  Fly   922 RKMQDPLVEYSQLCDADDEILCLRYHPLQERVPREQLLEQLSLQFINRTSEVGLDINLMVQNSRT 986
            |.:|:||...:.||....|||..:.|||:..:..::....:....::.|::||:||||...:...
plant   858 RYLQNPLAMVATLCGPGREILSWKLHPLENFLQLDEKYGMVEQVMVDITNQVGIDINLAASHDWF 922

  Fly   987 INLLQYICGLGPRKGQALLKLLKQSNQRLENRTQLVTVCH-LGPRVFINCSGFIKIDTSSLGDST 1050
            .:.||:|.||||||..:|.:.|.::......:.   .:.| ||.:||:|.:||::|..|.|..|:
plant   923 FSPLQFISGLGPRKAASLQRSLVRAGSIFVRKD---LIMHGLGKKVFVNAAGFLRIRRSGLAASS 984

  Fly  1051 EAYVEVLDGSRVHPETYEWARKMAIDAMEYD------DEETNPAGALEEILESPERLKDLDLDAF 1109
            ..::::||.:|:|||:|..|:::|.|..:.|      |:|.....|:|.:.:.|..|:.:.||.:
plant   985 SQFIDLLDDTRIHPESYSLAQELAKDIYDEDVRGDSNDDEDAIEMAIEHVRDRPASLRKVVLDEY 1049

  Fly  1110 AVELERQGFGSKSITLYDIRNELSCLYKDYRTPYTKPSAEELFDMLTKETPDSFYVGKCVTAMVT 1174
            ....:|:   :|..|..:|..||||.::|:|.|:.:||.:|.|.|::.||.|:...|:.|.|.|
plant  1050 LASKKRE---NKKETYSNIIRELSCGFQDWRIPFKEPSPDEEFYMISGETEDTIAEGRIVQASV- 1110

  Fly  1175 GFTYRRPQGDQLDSANPVRLDSNESWQCPFCHKDDFPELSEVWNHFDANACPGQPSGVRVRLENG 1239
                ||.|..:                 ..|                             .|::|
plant  1111 ----RRLQNGR-----------------AIC-----------------------------VLDSG 1125

  Fly  1240 LPGFIHIKNLSD--RQVRNPEERVRVSQMIHVRIIKIDIDRFSVECSSRTADLKDVNNEWRPRRD 1302
            |.|.:..::.||  |.:.:..::::...::..:|..|...|:.|....:.:::::..::.....|
plant  1126 LTGMLMKEDFSDDGRDIVDLADQLKEGDILTCKIKSIQKQRYQVFLICKESEMRNNRHQHNQNVD 1190

  Fly  1303 NYYDYVTEEQDNRKVSDAKAR---ALKRKIYARRVIAHPSFFNKSYAEVVAMLAEADQGEVALRP 1364
            .||.   |::::.::...|||   .|.||.:..|:|.||.|.|.:..:....|::.|.||..:||
plant  1191 AYYH---EDRNSLQLVKEKARKEKELVRKHFKSRMIVHPRFQNITADQATEYLSDKDFGESIVRP 1252

  Fly  1365 SSKSKDHLTATWKVADDIFQHIDVREEGKEN-DFS----LGRSLWIGTEEFEDLDEIIARHIMPM 1424
            ||:..:.||.|.|:.|.::.|.::.|.|||| |.:    :|::|.||.:.||||||::.|::.|:
plant  1253 SSRGLNFLTLTLKIYDGVYAHKEIAEGGKENKDITSLQCIGKTLTIGEDTFEDLDEVMDRYVDPL 1317

  Fly  1425 ALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKANDPKKIHYFFTASRAMPGKFLLSYLPKT 1489
            ....:.::.|:.::    .|.::|   ::.|||.||..:|.:|.|.|..|...||.|:|||:..|
plant  1318 VSHLKTMLNYRKFR----KGTKSE---VDDLLRIEKGENPSRIVYCFGISHEHPGTFILSYIRST 1375

  Fly  1490 KVRHEYVTVMPEGYRFRGQIFDTVNSLLRWFKEHWLDP--TATPASASASNLTPLHLMRPPPTIS 1552
            ...|||:.:.|:|::||.::|:.::.|:.:|:.|..||  .:.|:..|.:...|   ||.|....
plant  1376 NPHHEYIGLYPKGFKFRKRMFEDIDRLVAYFQRHIDDPLQESAPSIRSIAAKVP---MRSPADHG 1437

  Fly  1553 S-------SSQTSLGPQAPYSVTGSVTGGTPR---------SGISSAVGG--------------- 1586
            |       |||:..|.:.....:||..||..|         ||.....||
plant  1438 SSGGSGWGSSQSEGGWKGNSDRSGSGRGGEYRNGGGRDGHPSGAPRPYGGRGRGRGRGRRDDMNS 1502

  Fly  1587 ---GGSSAYSITQSIT---GYGTSGSSAPGAGVSSSHYGSSSTPSFGAINTPYTPSGQTPFMTPY 1645
               .|:..:....:.|   |:|.||....|:..:....|..||..:|
plant  1503 DRQDGNGDWGNNDTGTADGGWGNSGGGGWGSESAGKKTGGGSTGGWG------------------ 1549

  Fly  1646 TPHASQTPRYGHNVPSPSSQSSSSQRHHYGSSSGTGSTPRY-HDMGG------GGGGGVGGGGGS 1703
                           |.|..:.|.....:||.||.|.:..: :|.||      ||.|...|||||
plant  1550 ---------------SESGGNKSDGAGSWGSGSGGGGSGGWGNDSGGKKSSEDGGFGSGSGGGGS 1599

  Fly  1704 NAYSMQPHHQQRAKENLDWQLANDAWARRRPQQHQSHQSYHAQQQHHHSQQQPHMGMSMNMGITM 1768
                             ||  .|::..::                           .|.:.|
plant  1600 -----------------DW--GNESGGKK---------------------------SSADGG--- 1615

  Fly  1769 SLGRGTGG---GGGGGYGSTPVNDYSTGGG 1795
             .|..:||   .|.||:|:.|.:..|.|||
plant  1616 -WGSESGGKKSDGEGGWGNEPSSRKSDGGG 1644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt6	NP_001284936.1	HTH_44	308..411	CDD:291314	33/128 (26%)
		RuvC_resolvase	781..935	CDD:304378	32/159 (20%)
		HHH_5	939..1042	CDD:304555	32/103 (31%)
		DLD	1057..1159	CDD:291540	35/107 (33%)
		S1	1220..1281	CDD:278972	10/62 (16%)
		SH2_2	1309..1523	CDD:291307	75/221 (34%)
		SH2_Nterm_SPT6_like	1336..1420	CDD:198174	34/88 (39%)
		SH2_Cterm_SPT6_like	1429..1524	CDD:198182	30/94 (32%)
GTB1	NP_001321759.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	141	1.000	Domainoid score	I1521
eggNOG	1	0.900	-	-		E1_COG2183
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40661
Inparanoid	1	1.050	513	1.000	Inparanoid score	I299
OMA	1	1.010	-	-		QHG55107
OrthoDB	1	1.010	-	-		D56990at2759
OrthoFinder	1	1.000	-	-		FOG0004092
OrthoInspector	1	1.000	-	-		otm2407
orthoMCL	1	0.900	-	-		OOG6_102925
Panther	1	1.100	-	-	LDO	PTHR10145
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2838
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840