|
Fly 1 MAEFLDSEAEESEEE--EELDVNERKRLKKLKAAVSDSSEEEEDDEERLREELKDLIDDNPI--- 60
|::|::||||||||| .|.:|..|...|.::....|..|||..|::..|..|||.|:|:..
Rat 1 MSDFVESEAEESEEEYNHEGEVVPRVTKKFVEEEDDDEEEEENLDDQDERGNLKDFINDDDDEEE 65
Fly 61 -EEDDG--SGYDSDGVGSGKKRKKHEDDDLDDRLEDDDYDLIEENLGVKVERRKRFKRLRRIHDN 122
|||:| ||...|.||. ||||: ...||||||||:|||||||||||:|.::::|::::.|:
Rat 66 GEEDEGSDSGDSEDDVGH-KKRKR---TSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDD 126
Fly 123 ESDGEEQHVDEGLVREQIAEQLF-DENDESIGHRSERSHREADDYDDVDTESDADDFIVDDNGRP 186
:.|.||::..|...:|.||.::| ||..|......|......|:.::.|.|||.|||||||:|:|
Rat 127 DEDDEEEYGKEEHEKEAIAGEIFQDEEGEEGQEAVEAPMAPPDEEEEDDEESDIDDFIVDDDGQP 191
Fly 187 IAEKK-KKRRPIFTDASLQEGQDIFGVDFDYDDFSKYEEDDYEDDSEGD-EYDEDLGVGDDTRVK 249
:.:.| :|:.|.:|||:|||.|:|||||||||:|.||.| |:::.|.| ||::|...| :.||:
Rat 192 LKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNE--YDEELEEDYEYEDDEAEG-EIRVR 253
Fly 250 KKKALKKKVVKKTIFDIYEPSELKRGHFTDMDNEIRKTDIPERMQLREVPVTPVPEGSDELDLEA 314
.||..||:|.:::||::||||||:..|.||.|||||.||:|||.|||.:||....: |||:.||
Rat 254 PKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKAAED--DELEEEA 316
Fly 315 EWIYKYAFCKHTVSEQEKPESREK-------MRKPPTTVNKIKQTLEFIRNQQLEVPFIAFYRKE 372
:|||:.||...|:|.|:..:..:: .||.|:||.|||:.|.|:|||..|||||||||||
Rat 317 DWIYRNAFATPTISLQDSCDYLDRGQPTSSFSRKGPSTVQKIKEALGFMRNQHFEVPFIAFYRKE 381
Fly 373 YVKPELNIDDLWKVYYYDGIWCQLNERKRKLKVLFEKMRQFQLDTLCADTDQPVPDDVRLILDSD 437
||:|||:|:|||:|:.:|..|.||..||..|..|||||:.:|.:.:.||.|:|:.|.:|.:..:|
Rat 382 YVEPELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTD 446
Fly 438 FERLADVQSMEELKDVHMYFLLNYSHELPRMQ--AEQRRKAIQERREAKARRQAAAAENGDDAAE 500
.|||.|||||:|||||:.:|||.|..::|:|| |:..||.::..: |:||:..|
Rat 447 MERLKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAKASRKKLKRIK-----------EDGDEEGE 500
Fly 501 AIVVPEPEDDDDPELIDYQLKQASNSSPYAVFRKAGICGFAKHFGLTPEQYAENLRDNYQRNEIT 565
. |:.:|.|....:|||||....|.:.:.||:.|.||.|||||||:.|||||:|||:|..
Rat 501 G------EEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDSYQRHETE 559
Fly 566 QESIGPTELAKQYLSPRFMTTDEVIHAAKYVVARQLAQEPLLRKTMREVYFDRARINIRPTKNGM 630
|....|.||||.|:..:|.|.:.|:..|:|:||.|:|:|||:|:.:|:.:.:||::||.|||.|.
Rat 560 QFPAEPLELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGR 624
Fly 631 VLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLEITFLEEFEGNACANGTPGD--YVE 693
..:||....||.||:..|||.:|..|||:|:.:||:|.||.|....:.:| ..|...| |.|
Rat 625 KDVDEAHYAYSFKYLKNKPVKELRDDQFLKIGLAEDEGLLTIDISIDMKG---VEGYGNDQTYFE 686
Fly 694 ESKALYQLDQFAKHVQEWNKLRAECVQLALQKWVIPDLIKELRSTLHEEAQQFVLRSCTGKLYKW 758
|.|..|..|:|:..|||||:.|...::.|||:::...:.|||::.|..||::.|:::|:.|||.|
Rat 687 EIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEARESVVKACSRKLYNW 751
Fly 759 LKVAPYKP--QLPPDFGYEEWSTLRGIRVLGLAYDP--DHSVAAFCAVTTVEGDISDYLRLPNIL 819
|:||||:| |:..|..:.:.:..:||||||:|:.. ||.| |||:...||:::|:||||:..
Rat 752 LRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPV--FCALVNGEGEVTDFLRLPHFT 814
Fly 820 KRKNSYNLEEKAQKLADLRKLSDFIKMKKPHIVVIGAESRDAQNIQADIKEILHELETSEQFPPI 884
||:.::..||:.:|..|:..|..|:..||||:|.:..|:||||.:..|:|.|:|||:..:|...|
Rat 815 KRRTAWREEEREKKAQDIETLKKFLVNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQQLSSI 879
Fly 885 EVEIIDNELAKIYANSKKGESDFKEYPPLLKQAASLARKMQDPLVEYSQLCDADDEILCLRYHPL 949
.||::|||||.:|.||||.|::|::|||:|:||.||||::||||:|::|:|.:|::||||::|||
Rat 880 GVELVDNELAILYMNSKKSEAEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPL 944
Fly 950 QERVPREQLLEQLSLQFINRTSEVGLDINLMVQNSRTINLLQYICGLGPRKGQALLKLLKQSNQR 1014
||.|.:|:||..|..:||||.:|||:|:|..:.:..:..|:||:||||||||..|||:|||:|.|
Rat 945 QEHVVKEELLNALYCEFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTR 1009
Fly 1015 LENRTQLVTVCHLGPRVFINCSGFIKIDTSSLGDSTEAYVEVLDGSRVHPETYEWARKMAIDAME 1079
||:||||||:||:||:||:||:||:||||:||||||::|:||||||||||||||||||||:||:|
Rat 1010 LESRTQLVTMCHMGPKVFMNCAGFLKIDTASLGDSTDSYIEVLDGSRVHPETYEWARKMAVDALE 1074
Fly 1080 YDD--EETNPAGALEEILESPERLKDLDLDAFAVELERQGFGSKSITLYDIRNELSCLYKDYRTP 1142
||: |:.|||||||||||:|||||||||||||.||||||:|.|.|||||||.||||.|||.||.
Rat 1075 YDESAEDANPAGALEEILENPERLKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTA 1139
Fly 1143 YTKPSAEELFDMLTKETPDSFYVGKCVTAMVTGFTYRRPQGDQLDSANPVRLDSNESWQCPFCHK 1207
|..|:.||:|:|||||||::||:||.:...|||..:|||||:..|.| :|.|....||||||.:
Rat 1140 YRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQ 1202
Fly 1208 DDFPELSEVWNHFDANACPGQPSGVRVRLENGLPGFIHIKNLSDRQVRNPEERVRVSQMIHVRII 1272
|:||||||||||||:.:||||..||:.||:||:.|||..|.|||:.|:.|||||:|...:|.||:
Rat 1203 DNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMTVHCRIM 1267
Fly 1273 KIDIDRFSVECSSRTADLKDVNNEWRPRRDNYYDYVTEEQDNRKVSDAKARALKRKIYARRVIAH 1337
||||::||.:.:.||:||.|.||||:..:|.|||:..|..|:::..|.| |..:|..|.:|||||
Rat 1268 KIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK-RKQQRTTYIKRVIAH 1331
Fly 1338 PSFFNKSYAEVVAMLAEADQGEVALRPSSKSKDHLTATWKVADDIFQHIDVREEGKENDFSLGRS 1402
|||.|.::.:...|:...|||:|.:|||||.::|||.||||:|.|:||:|||||||||.||||.:
Rat 1332 PSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQHVDVREEGKENAFSLGAT 1396
Fly 1403 LWIGTEEFEDLDEIIARHIMPMALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKANDPKKI 1467
|||.:|||||||||:||::.|||..||:|:.:|||: :...|| |..:|:||.:.|...|..|
Rat 1397 LWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQ-DCSGGD---RKKLEELLIKTKKEKPTFI 1457
Fly 1468 HYFFTASRAMPGKFLLSYLPKTKVRHEYVTVMPEGYRFRGQIFDTVNSLLRWFKEHWLDPT--AT 1530
.||..|.:.:||||||.|.|:.|.|.|||||.|||:|:|||||.|||.|.||||:|:.||. .|
Rat 1458 PYFICACKELPGKFLLGYQPRGKPRIEYVTVTPEGFRYRGQIFPTVNGLFRWFKDHYQDPVPGIT 1522
Fly 1531 PASASASNLTPLHLMRPPPTISSSSQTSLGPQAPYSVTGSVTGGTPRSGISSAVGGGGSSAYSIT 1595
|:|:|.:. ||..:...|..|:.:..|......|.::| |..:|..
Rat 1523 PSSSSRTR-TPASINATPANINLADLTRAVNALPQNMT--------------------SQMFSAI 1566
Fly 1596 QSITGYGTSGSSAPGAGVSSSH-YGSS--STPSFGAINTPYTPSGQTPFMTPYTPHASQTPRYGH 1657
.::||.|.:.::.|....||.: ||.| .:.::....|| .|.|..||. .||.|.:
Rat 1567 AAVTGQGQNPNATPAQWASSQYGYGGSGGGSSAYHVFPTP----AQQPVATPL-----MTPSYSY 1622
Fly 1658 NVPSPSSQSSSSQRHHYGSSSGTGSTPRYHDMGGGGGGGVGGGGGSNAYSMQP-----HHQQRAK 1717
..| ||..::.::|...:| :||: |.....|| ..||:.|
Rat 1623 TTP---SQPITTPQYHQLQAS---TTPQ-----------------STQAQPQPSSSSRQRQQQPK 1664
Fly 1718 EN----LDWQLANDAWARRRPQQHQSHQSYHAQQQHHHSQQQPHMGMSMNMGITMSLGRGTGGGG 1778
.| :||....:.|.:.:..:.:
Rat 1665 SNSHAAIDWGKMAEQWLQEKEAERR---------------------------------------- 1689
Fly 1779 GGGYGSTPVNDYSTGGGHNRGMSSKASVRSTPRTNASP----HSMNL-GDATPLYDE 1830
|...|.|||.:.|| ..|:: ||||||.||
Rat 1690 ------------------------KQKQRLTPRPSPSPMIESTPMSIAGDATPLLDE 1722
| 
