Protein Alignment trbl and Trib3

DIOPT Version :9

• Sequence 1: NP_524672.1
• Gene: trbl / 43999
• FlyBaseID: FBgn0028978
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_780302.2
• Gene: Trib3 / 228775
• MGIID: 1345675
• Length: 354
• Species: Mus musculus
• Alignment Length: 342
• Identity: 114/342 - (33%)
• Similarity: 161/342 - (47%)
• Gaps: 68/342 - (19%)

  Fly   115 SHISAAVAAKT-------------PASYRHLVDLTASNLRCVDIFTGEQFLCRIVNEPLHKVQRA 166
            |.:|.|||..|             ..|||        .|.|.   ||.::.|::.  |..:.|..
Mouse    56 SDLSPAVAPATRLGPYILLEREQGSCSYR--------ALHCP---TGTEYTCKVY--PASEAQAV 107

  Fly   167 ---YFQLQQHDEELR-RSTIYGHPLIRPVHDIIPLTKDRTYILIAPVPQERDSTGGVTGVYENLH 227
               |.:|..|....| ...:.|..|:              ||..             |..:.:||
Mouse   108 LAPYARLPTHQHVARPTEVLLGSRLL--------------YIFF-------------TKTHGDLH 145

  Fly   228 TYIRHAKRLCETEARAIFHQICQTVQVCHRNGIILRDLKLKRFYFIDEARTKLQYESLEGSMILD 292
            :.:|..:.:.|:||..:|.|:...|..||::|::||||||:||.|.:..||||..|:||.:.::.
Mouse   146 SLVRSRRGIPESEAAGLFRQMASAVAHCHKHGLVLRDLKLRRFVFSNCERTKLVLENLEDACVMT 210

  Fly   293 GEDDTLSDKIGCPLYTAPELLCPQQTYKGKPADMWSLGVILYTMLVGQYPFYEKANCNLITVIRH 357
            |.||:|.||..||.|..||:|..:.:|.||.||:|||||.|:|||.|:|||::.....|...||.
Mouse   211 GSDDSLWDKHACPAYVGPEILSSRPSYSGKAADVWSLGVALFTMLAGRYPFHDSEPVLLFGKIRR 275

  Fly   358 GNVQIPLTLSKSVRWLLLSLLRKDYTERMTASHIFLTPWLREQRPFHMYLPVDVEVAEDWSDAEE 422
            |...:|..||...|.|:..||||:.:||:.|..|.|.|||||...         .|:...||..|
Mouse   276 GTFALPEGLSAPARCLIRCLLRKEPSERLVALGILLHPWLREDHG---------RVSPPQSDRRE 331

  Fly   423 DEGTAADA--MDDDEEG 437
            .:....|.  :::.|||
Mouse   332 MDQVVPDGPQLEEAEEG 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trbl	NP_524672.1	PKc_like	131..397	CDD:328722	93/269 (35%)
Trib3	NP_780302.2	Interaction with DDIT3/CHOP. /evidence=ECO:0000250	1..127		20/83 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..61		2/4 (50%)
		S_TKc	71..315	CDD:214567	96/283 (34%)
		PKc_like	74..315	CDD:304357	96/280 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	320..354		8/38 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849865
Domainoid	1	1.000	181	1.000	Domainoid score	I3461
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3924
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001790
OrthoInspector	1	1.000	-	-		otm42850
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22961
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1487
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.950