DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trbl and stk40

DIOPT Version :9

Sequence 1:	NP_524672.1	Gene:	trbl / 43999	FlyBaseID:	FBgn0028978	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_001120455.1	Gene:	stk40 / 100145549	XenbaseID:	XB-GENE-1007328	Length:	443	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	79/275 - (28%)
Similarity:	124/275 - (45%)	Gaps:	73/275 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 NLHTYIRHAKRLCETEARAIFHQICQTVQVCHRNGIILRDLKLKRFYFIDEARTKLQYESLEGSM 289
            ||..|:...|||.|.|...||:.:.:.|:..|:..|:.|||||                   |:|
Frog   158 NLQHYVIKEKRLGERETVVIFYDVVRVVEALHKKNIVHRDLKL-------------------GNM 203

  Fly   290 ILD------------------GEDDTLSDKIGCPLYTAPELLCPQQTYKGKPADMWSLGVILYTM 336
            :|:                  .|||.|.|:.|.|.|.:|::| ..:.|:|||:|||:|||:|:||
Frog   204 VLNKRTHRITVTNFCLGKHLVSEDDLLKDQRGSPAYISPDVL-SGRPYRGKPSDMWALGVVLFTM 267

  Fly   337 LVGQYPFYEKANCNLITVIRHGNVQIPL--TLSKSVRWLLLSLLRKDYTERMTASHI------FL 393
            |.||:|||:.....|...|:.....||.  .:|:|...|:..||..|..:|:|||.:      .:
Frog   268 LYGQFPFYDSIPQELFRKIKAAEYSIPEDGRVSESTVCLIRKLLVLDPQQRLTASEVLESLGAII 332

  Fly   394 TPWLREQRPFHMYLPV----DVEVAEDWSDAEEDEGTAADAMDDDEEGLCPLGDKHEYEDIGVEP 454
            :.|   |....:..|:    |::......:::|.:.|        ||     ..::|:|
Frog   333 SSW---QSMSSLSGPLQVVPDIDHLTSLENSQEAKVT--------EE-----SSQYEFE------ 375

  Fly   455 LDYTRSTLQMAQNAN 469
             :|.|..|.:|:..|
Frog   376 -NYMRQQLLLAEEKN 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trbl	NP_524672.1	PKc_like	131..397	CDD:328722	64/197 (32%)
stk40	NP_001120455.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
stk40	NP_001120455.1	STKc_SHIK	38..330	CDD:270876	64/191 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362510at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920