Protein Alignment jbug and alpha-Spec

DIOPT Version :10

• Sequence 1: NP_001261140.1
• Gene: jbug / 43997
• FlyBaseID: FBgn0028371
• Length: 2990
• Species: Drosophila melanogaster
• Sequence 2: NP_001261286.1
• Gene: alpha-Spec / 38231
• FlyBaseID: FBgn0250789
• Length: 2457
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 124/715 - (17%)
• Similarity: 220/715 - (30%)
• Gaps: 257/715 - (35%)

  Fly  2177 RQHIGS-------RTLCVFDPTLVKITEVSEAFCHRPASIGVSLNEAGQGDLSALVRCGATEVPH 2234
            :||..:       :.:.|...|||:.::..          |..||||          |...:...
  Fly   644 KQHYAADQINTRMQEIVVLWETLVQASDKK----------GTKLNEA----------CQQQQFNR 688

  Fly  2235 TIRGPSKTGVYEIVYQPTRVAPHKISILFNEVPISLKPLEINVLPASAGKEI-SVSGLG------ 2292
            ||                           .::.:.|..:|..:|....||:: ||..|.
  Fly   689 TI---------------------------EDIELWLSEIEGQLLSEDHGKDLTSVQNLQKKHALL 726

  Fly  2293 -----LYQSRVGKTTSFAIDTVKRPAREFDVVVSGPGGQALPVRCYQTKNGHLQAEFTINKPGQC 2352
                 .:|.|        |:::|..|.:|                  .::||..|:...||.|..
  Fly   727 EADVMAHQDR--------IESIKVAANKF------------------IESGHFDADNIRNKEGNL 765

  Fly  2353 VIEVLHQSKPLPGSPFTCESFDSSKVSTQGVTKEPL--ALHSPNSFTVRTDNAG-TAELEAFAIS 2414
            .......:.|:                  |..|:.|  :|.....|....|.|. ..|.|..|.|
  Fly   766 SARYAALAAPM------------------GERKQHLLDSLQVQQLFRDLEDEAAWIREKEPIAAS 812

  Fly  2415 PSNQSIPVLISEQSDGVYNV----EFVPSQPGNYKLTLMYGGETIPSSPLNFTASSSGVRNDAR- 2474
             :|:...::      ||.|:    :.|.::..|::..|:    .:.||..|.........:|.|
  Fly   813 -TNRGRDLI------GVQNLIKKHQAVLAEINNHEARLL----NVISSGENMLKDQPFASDDIRQ 866

  Fly  2475 ---------------------------------AAGHGLEVCHRNKEASFVVYCPIAPNVQIERL 2506
                                             |..:..|...|.||       |||......:.
  Fly   867 RLEALQEQWNTLKEKSSQRKQDLDDSLQAHQYFADANEAESWMREKE-------PIATGSDYGKD 924

  Fly  2507 DEYGERIEPKIKALGNNEWRISYTILSVGKYEIRASCPNRGS----LPG-------------SPW 2554
            ::..|.:..|.:||.::......||.::  .|...:|..:.:    :.|             ||.
  Fly   925 EDSSEALLKKHEALVSDLEAFGNTIQAL--QEQAKNCRQQETPVVDITGKECVVALYDYTEKSPR 987

  Fly  2555 HISCVESNKVTPVGG----WGTLVDHDGRLILPARIIFDVENAGPGKLVCSIDGIEIPVDKLVDG 2615
            .:|..:.:.:|.:..    |..:..:|.:..:||..|..::           .|:......|||
  Fly   988 EVSMKKGDVLTLLNSNNKDWWKVEVNDRQGFVPAAYIKKID-----------AGLSASQQNLVD- 1040

  Fly  2616 KMCLNITGENLAAGEHDLDLTWSGLTITQCPR--------SAFVTGQQAADKVQ----------- 2661
                   ..::|..::.::..:..|......|        .|:|..::|||..|
  Fly  1041 -------NHSIAKRQNQINSQYDNLLALARERQNKLNETVKAYVLVREAADLAQWIRDKENHAQI 1098

  Fly  2662 --LMGRGLAAAQAGEAAHFTIDASNAPAGRPEVILTSQDNTSLPV-SLAQPRPSENIWLASYTPL 2723
              ::|..|   :..|......|..|......||.|.:.:..::.: ||.|...:          |
  Fly  1099 ADVVGEDL---EEVEVLQKKFDDFNDDLKANEVRLANMNEIAVQLTSLGQTEAA----------L 1150

  Fly  2724 KSTTGTLNLSVKWNGRLVKGCPLTVAVGSS---------MDASK--VIVSGEGLRHGIVGKDIKS 2777
            |..|...:|:.|||............:||:         :|.:|  :......|.:..:|||::|
  Fly  1151 KIQTQMQDLNEKWNNLQTLTAEKASQLGSAHEVQRFHRDIDETKDWIAEKANALNNDDLGKDLRS 1215

  Fly  2778  2777
              Fly  1216  1215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jbug	NP_001261140.1	CH_jitterbug-like_rpt1	57..166	CDD:409076
		CH_jitterbug-like_rpt2	170..274	CDD:409078
		CH_jitterbug-like_rpt3	275..373	CDD:409034
		IG_FLMN	468..560	CDD:214720
		IG_FLMN	560..648	CDD:214720
		IG_FLMN	1119..1198	CDD:214720
		IG_FLMN	1220..1302	CDD:214720
		IG_FLMN	1310..1389	CDD:214720
		IG_FLMN	1399..1480	CDD:214720
		IG_FLMN	1480..1569	CDD:214720
		IG_FLMN	1575..1659	CDD:214720
		IG_FLMN	1661..1747	CDD:214720
		IG_FLMN	1757..1837	CDD:214720
		IG_FLMN	1837..1926	CDD:214720
		IG_FLMN	1936..2023	CDD:214720
		Filamin	2021..2111	CDD:395505
		IG_FLMN	2198..2280	CDD:214720	11/81 (14%)
		IG_FLMN	2285..2375	CDD:214720	16/101 (16%)
		IG_FLMN	2376..2465	CDD:214720	21/95 (22%)
		Filamin	2474..2555	CDD:395505	20/131 (15%)
		IG_FLMN	2657..2751	CDD:214720	21/107 (20%)
		IG_FLMN	2756..2847	CDD:214720	6/24 (25%)
		IG_FLMN	2850..2944	CDD:214720
alpha-Spec	NP_001261286.1	SPEC	48..258	CDD:238103
		SPEC	154..364	CDD:238103
		SPEC	261..470	CDD:238103
		SPEC	471..680	CDD:238103	9/45 (20%)
		SPEC	682..893	CDD:238103	46/292 (16%)
		Spectrin	893..>961	CDD:395348	16/76 (21%)
		SH3_Alpha_Spectrin	974..1026	CDD:212742	9/51 (18%)
		SPEC	1074..1287	CDD:238103	33/155 (21%)
		SPEC	1182..1425	CDD:238103	7/34 (21%)
		SPEC	1426..1638	CDD:238103
		SPEC	1533..1744	CDD:238103
		SPEC	1646..1850	CDD:238103
		SPEC	1852..2062	CDD:238103
		SPEC	1958..2176	CDD:238103
		SPEC	2072..2296	CDD:238103
		EFh	2311..2379	CDD:238008
		EFhand_Ca_insen	2386..2456	CDD:430177