Protein Alignment jbug and Dyb

DIOPT Version :10

• Sequence 1: NP_001261140.1
• Gene: jbug / 43997
• FlyBaseID: FBgn0028371
• Length: 2990
• Species: Drosophila melanogaster
• Sequence 2: NP_001097287.1
• Gene: Dyb / 36362
• FlyBaseID: FBgn0033739
• Length: 816
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 112/548 - (20%)
• Similarity: 181/548 - (33%)
• Gaps: 132/548 - (24%)

  Fly  1531 SARFSVSFVPTESC----------EHTINVSFNKMPVP-----GCPITVSISGGVAGPQVSLGGP 1580
            |.|.|...||.::.          |.|:|:|....|.|     |......:..|..||...|.|.
  Fly   293 SLRKSFRCVPEKTVQVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPGLPGQ 357

  Fly  1581 GPVHQTNSFVINHNGGRLEDIEVNVEGPAGQSVPAQVHQSADGV---FKAEFVPRVVGEHRV--N 1640
            ..:...:|.:.:...||..|   :..|.||.::......||:..   ..|.:..|:..|:|.  |
  Fly   358 HGLFDRSSTLDSRATGRSLD---SASGTAGTTMSRVAAASANDEEHRLIARYAARLAQENRAPSN 419

  Fly  1641 VTVNGLPTAGSPYAAKVYDVSAIKVKNVSSGTVGKAVTFL---VETSQAGPGNLEVTVNGGRVPT 1702
            :..|..|.......|:...::.::.||..   :.:.:..|   .||.|..|.| ...:|  .:..
  Fly   420 LPDNATPIGTDNSRAQRELIAQLESKNKE---IMREIARLRRQQETEQMAPEN-PALIN--ELRA 478

  Fly  1703 SAQAQGQHTYAISFTPREAESHTVELRFNSQDVPGSPFTCRVAAAARIQSPETMDKVSVGRLFEF 1767
            ..|.:|           |.|.|...|    ||             :|.|..|.::  .:.|:.:.
  Fly   479 LRQRKG-----------ELEGHLGAL----QD-------------SRRQLMEQLE--GLMRMLKN 513

  Fly  1768 VVESDTKPTVEVLGPARRSVPVKIDA--LGSSTL----GYNVKFEPMEVGDHSVEVRL------P 1820
            ...:..:.|......:.:|.|:...|  ||:|.:    ...::..||..|..:.:.:|      .
  Fly   514 QQTASPRSTPNSSPRSGKSPPMPGGAGILGTSPMSALHAQQMQQHPMAGGVRASQQQLLQQQQQQ 578

  Fly  1821 GGGHVEGSPFLLKAYSAEKVIVTDIRAGVVNKSVSFGINASQAGAGNLEIIVAVNGKNVPNFVQ- 1884
            ..||   .||..........|.:|:|:       :|..|.|.............|...:|:...
  Fly   579 AHGH---GPFSQSQLEQLNQISSDMRS-------AFAANGSATPPPMRTTTATANVSAIPSLNPI 633

  Fly  1885 SEGNARFKVNFKPTEAATHSLSVRFNGHPVPGSPFSCHIAAAAASPSMGLPRAMAMG----ECLK 1945
            |..|.....:.:..|||.|..|.               |:...:..:.|..||..:|    ..:.
  Fly   634 SNQNPNLNPDAELNEAADHLTSA---------------ISHMVSDLNAGRGRAQQLGPQPASSIP 683

  Fly  1946 QAAVKMDNTF-ELEGFDGVEPQIFVTSPSGDNEHCQLSQHDGGSYSASFRPTTVGRHLISVTAND 2009
            ||...|...| .:||           ..|.|:..|:.:..:.|.|...||           |..|
  Fly   684 QARFIMPLEFRHIEG-----------GESEDSSQCECNDCECGEYEEVFR-----------TDED 726

  Fly  2010 QHING--SPFSCNVFDVSRVSISGLEQQ 2035
            ....|  :||. |.:  |....||:.::
  Fly   727 LECEGAAAPFG-NAY--SLFPTSGVHEE 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jbug	NP_001261140.1	CH_jitterbug-like_rpt1	57..166	CDD:409076
		CH_jitterbug-like_rpt2	170..274	CDD:409078
		CH_jitterbug-like_rpt3	275..373	CDD:409034
		IG_FLMN	468..560	CDD:214720
		IG_FLMN	560..648	CDD:214720
		IG_FLMN	1119..1198	CDD:214720
		IG_FLMN	1220..1302	CDD:214720
		IG_FLMN	1310..1389	CDD:214720
		IG_FLMN	1399..1480	CDD:214720
		IG_FLMN	1480..1569	CDD:214720	12/52 (23%)
		IG_FLMN	1575..1659	CDD:214720	19/88 (22%)
		IG_FLMN	1661..1747	CDD:214720	17/88 (19%)
		IG_FLMN	1757..1837	CDD:214720	16/91 (18%)
		IG_FLMN	1837..1926	CDD:214720	16/89 (18%)
		IG_FLMN	1936..2023	CDD:214720	22/93 (24%)
		Filamin	2021..2111	CDD:395505	3/15 (20%)
		IG_FLMN	2198..2280	CDD:214720
		IG_FLMN	2285..2375	CDD:214720
		IG_FLMN	2376..2465	CDD:214720
		Filamin	2474..2555	CDD:395505
		IG_FLMN	2657..2751	CDD:214720
		IG_FLMN	2756..2847	CDD:214720
		IG_FLMN	2850..2944	CDD:214720
Dyb	NP_001097287.1	EFh_DTN	45..205	CDD:320002
		EF-hand-like motif	45..86	CDD:320002
		EF-hand-like motif	95..129	CDD:320002
		EF-hand-like motif	135..171	CDD:320002
		EF-hand-like motif	182..205	CDD:320002
		ZZ_dystrophin	232..280	CDD:239074
		CwlO1	376..691	CDD:443091	73/378 (19%)
		ClpA	<430..>514	CDD:440308	22/119 (18%)