Protein Alignment jbug and anc-1

DIOPT Version :10

• Sequence 1: NP_001261140.1
• Gene: jbug / 43997
• FlyBaseID: FBgn0028371
• Length: 2990
• Species: Drosophila melanogaster
• Sequence 2: NP_491353.2
• Gene: anc-1 / 172034
• WormBaseID: WBGene00000140
• Length: 8545
• Species: Caenorhabditis elegans
• Alignment Length: 1106
• Identity: 214/1106 - (19%)
• Similarity: 377/1106 - (34%)
• Gaps: 306/1106 - (27%)

  Fly    51 RGNEDLWVEIQANTFRNWVNEHLRE--TGMQVHDWATDFCDGTCLCALVENLQTRPLKPSWNRRP 113
            |.:||  .:.|.|||..|:|.||.|  :..::.|...|..||..||.|:|.|....|.....|..
 Worm    17 RPHED--EKAQKNTFTRWINFHLEEHSSSGRIEDLFEDIRDGVLLCHLIEVLTGEALAVHKGRVS 79

  Fly   114 ANQHHYLENATTALKSIEADHIKLVNIGNVDIVNGNIKLILGLIWSLIVRYQIGRSKFPPRKLML 178
            ...|| :.|.||||..:....::|:|....||.:||.:::|||||.:|:.:||..:..    |:.
 Worm    80 KRVHH-IANLTTALTVLRRRGLELINNNAADIADGNPRIVLGLIWQIILHFQIETNMI----LLR 139

  Fly   179 AW----------LQAALPDCRIT--NLTTDWNSGVNLAALLDYCQPGLFPHWRSLDPSQSVRNCT 231
            .|          ..:|.|:..:|  :.|.......:..:.|...:..|....::  ||..:|
 Worm   140 EWGWAATGTEEPTSSAQPEVVVTAPSPTPSSKKSHSKVSSLSGSKTSLASGEKA--PSSPLR--- 199

  Fly   232 QAMDLAQR--EFGVPKVLEPEYLASPWLDELSGMTYLSYFMKPGGPGYNATMRWVNTQVKD---- 290
                  ||  .|..|....|:..|.|....:.                ...:||:|.::.|
 Worm   200 ------QRIASFLTPTKKAPKLTAQPVKQSVE----------------QVFLRWINAEIGDLVGG 242

  Fly   291 -PVKNFTTDWNDGRVMCEIIKGLGGSAPAPEKLS------TDPFHYENNIRKAVD-AGARLGVQP 347
             .|:|....|.||.:.|.::     |...|:.:|      .:|   .:|:..|.: |...|||:.
 Worm   243 RRVENMDKQWRDGILFCALV-----SRWRPDVISMREVTNANP---RDNLELAFNLAHQHLGVRR 299

  Fly   348 ILTAKDMANPEVEHLGIMAYAAH-LQWVPPRPPLS-----DLVSVYLESTSGRVGEPTHFRIDVM 406
            :|..:||...:.:...::.|.:. ::....|.|:.     ::...:||:|.            ::
 Worm   300 LLAVEDMMIEKPDKRSVITYVSQFVRMFGERSPMQGREQHEIFLAWLEATY------------LL 352

  Fly   407 SRDISLSSVRCHVVPPSGQPGQPVRLNAHGEGVFVPERYGMHEIV-VEIGEDSLGGHFFRALPRL 470
            .....|:|..|..:.......:|:    ....:.....|.:.|:| :|...|.:.....:...|.
 Worm   353 CTRHELNSQECSRIRREFIEHRPL----FNTIIVTKVNYDVEELVEIEKKWDCIRETLEKYARRS 413

  Fly   471 LQVAPPGMAPCA--LGSLVEVL-----VNATGAPKTEDILVTAVSPTGISHNCPLKKIDEGHSAI 528
            .:..|...|..|  :.....:|     ::||.|.||..:|...:|    .|...::.:
 Worm   414 ERDLPEPFASIATWIAGAEHILSRPLDLDATDAKKTVTMLQKLIS----EHQKYMEDL------- 467

  Fly   529 FKPDEAGIWEIAITYQGRHIQGGPFTCAVFDASGVSVHGLDGAMPLRAHTFEVDARGVGVSGELH 593
              |.....:|.|:.:.|   .||......|            :.||||...:::.
 Worm   468 --PKRQEDFEEAVKHGG---LGGRPVAPEF------------SEPLRARFAQIEE---------- 505

  Fly   594 VDIVHDKHSLVCSVEKIVENKYRVTFMPRQNGKYRVYIYFNGYDVKGSPFIMRVGTKGRSGKTRS 658
                              ||:.|::.:......|.:..|....|.|   .|:     .|:..:.:
 Worm   506 ------------------ENEPRISTLRILTTHYILLQYLQHIDEK---IIL-----WRTADSVT 544

  Fly   659 SPLHDSKH----RSESPSMHFVSTTN----TRHNDYRNSSL--------SRHNTAERTNSYSPQY 707
            ..|...|.    .:|:|.....|..|    |..|| :||.|        |...|||....:...:
 Worm   545 LLLRWIKEYTQLNAENPQAKCASYINKITLTMAND-QNSKLDKEAILNTSNEKTAETLKRFESLW 608

  Fly   708 SP----KLDTTDYHSSSSRYYKRESEENHATPPPAP-----------------PPASGSPTVKYL 751
            ..    |::..::.:..|:..:...|......||.|                 |....|..:...
 Worm   609 IELKLLKVEWVEWETHVSQLEEIIEERRRNGVPPTPEDEQALAVITAGADQLAPKLGASARLSNN 673

  Fly   752 NSADLYTET----------LNGR----RDSKTSNSSSTKNDYYYDKENELYSQRRAVTKPKLTPP 802
            ...|:.|.:          :.||    .:..||..:| |..|.:...:||.
 Worm   674 QRLDVLTHSFKKLTKTTIKIGGRLVVELEPSTSEQAS-KISYSWQASDELL-------------- 723

  Fly   803 REERELTSTTNTSSSSSFQQRHQQLATSTLTRSLSPIPSPTLNTRSSEVH-THSPLTIKTSNQYE 866
            :.|.:|.......:.||.:::.:..|.:........|....||    |:: .||      .:|.:
 Worm   724 KVEMQLRDRIQRDADSSDREQLEYRAETFRNIRDKLIELERLN----EIYDNHS------RDQVD 778

  Fly   867 SSTRNI-----------TSSPRHASVSPVQRYSPNSAYITTATHRMGSPLTSPVSKNGYESSRTV 920
            :..||:           ..:.::|:...:..|    |::....:::...||..|....|......
 Worm   779 TPNRNLIRHDMGTIIYGLQAGQYANFVDLSCY----AFVYDEYNQVPVNLTENVLSEDYVREIVN 839

  Fly   921 EKSSTYKSTSNYVTDSNIRASPSLYGTAERL----RRTGSPEPRIDHSSNVRVSSMKPASARRDS 981
            .|.:......|  .:..||.|.......:|:    :.|...|.|.:.  |:::|..       :|
 Worm   840 RKKAILTRREN--NEDEIRESIRDMEECDRIIEGWQSTEIEELRAEW--NIKLSEF-------ES 893

  Fly   982 W-------DVINKT-------------------KHMLSHN--------SLESLANMTEKQLNTEL 1012
            |       :|:::|                   .:.:.|:        |||.||..:|..:|..|
 Worm   894 WHEMMQQVEVLSQTIQTRLDVTVIQTIWILKERSYDIKHSELGGTLRESLEQLATTSETSVNRHL 958

  Fly  1013 Q 1013
            |
 Worm   959 Q 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jbug	NP_001261140.1	CH_jitterbug-like_rpt1	57..166	CDD:409076	39/110 (35%)
		CH_jitterbug-like_rpt2	170..274	CDD:409078	18/117 (15%)
		CH_jitterbug-like_rpt3	275..373	CDD:409034	24/110 (22%)
		IG_FLMN	468..560	CDD:214720	20/98 (20%)
		IG_FLMN	560..648	CDD:214720	12/87 (14%)
		IG_FLMN	1119..1198	CDD:214720
		IG_FLMN	1220..1302	CDD:214720
		IG_FLMN	1310..1389	CDD:214720
		IG_FLMN	1399..1480	CDD:214720
		IG_FLMN	1480..1569	CDD:214720
		IG_FLMN	1575..1659	CDD:214720
		IG_FLMN	1661..1747	CDD:214720
		IG_FLMN	1757..1837	CDD:214720
		IG_FLMN	1837..1926	CDD:214720
		IG_FLMN	1936..2023	CDD:214720
		Filamin	2021..2111	CDD:395505
		IG_FLMN	2198..2280	CDD:214720
		IG_FLMN	2285..2375	CDD:214720
		IG_FLMN	2376..2465	CDD:214720
		Filamin	2474..2555	CDD:395505
		IG_FLMN	2657..2751	CDD:214720
		IG_FLMN	2756..2847	CDD:214720
		IG_FLMN	2850..2944	CDD:214720
anc-1	NP_491353.2	CH_SF	20..132	CDD:469584	42/114 (37%)
		CH_SF	221..328	CDD:469584	24/130 (18%)
		PRK03918	2090..2716	CDD:235175
		PTZ00121	<2883..3913	CDD:173412
		PTZ00121	<3859..4867	CDD:173412
		PTZ00121	<4813..5770	CDD:173412
		PTZ00121	<5716..6673	CDD:173412
		PTZ00121	<6619..7576	CDD:173412
		PTZ00121	<7522..8211	CDD:173412
		KASH	<8507..8545	CDD:463142