Protein Alignment jbug and jbug

DIOPT Version :10

• Sequence 1: NP_001261140.1
• Gene: jbug / 43997
• FlyBaseID: FBgn0028371
• Length: 2990
• Species: Drosophila melanogaster
• Sequence 2: XP_061504219.1
• Gene: jbug / 1270096
• VectorBaseID: AGAMI1_009124
• Length: 2887
• Species: Anopheles gambiae
• Alignment Length: 2974
• Identity: 2036/2974 - (68%)
• Similarity: 2384/2974 - (80%)
• Gaps: 118/2974 - (3%)

  Fly     7 KGAKVTHAGLLKHNSDGTTETQKITHAGLVARSPEGTAAKGMNIRGNEDLWVEIQANTFRNWVNE 71
            ||||:||.|||:|..||.||.||||.|||||||||||||||||||||||||||||||||:|||||
Mosquito     5 KGAKITHTGLLQHTPDGKTELQKITQAGLVARSPEGTAAKGMNIRGNEDLWVEIQANTFKNWVNE 69

  Fly    72 HLRETGMQVHDWATDFCDGTCLCALVENLQTRPLKPSWNRRPANQHHYLENATTALKSIEADHIK 136
            ||||:|:||.::..||||||.||||||.||.||||||||:|||||||||||.||||.:||||.:|
Mosquito    70 HLRESGLQVIEFHEDFCDGTLLCALVEGLQKRPLKPSWNKRPANQHHYLENVTTALNAIEADGVK 134

  Fly   137 LVNIGNVDIVNGNIKLILGLIWSLIVRYQIGRSKFPPRKLMLAWLQAALPDCRITNLTTDWNSGV 201
            |||||||||||||:||||||||||||||||||||||||||||||||||||||:::||||||||||
Mosquito   135 LVNIGNVDIVNGNVKLILGLIWSLIVRYQIGRSKFPPRKLMLAWLQAALPDCKVSNLTTDWNSGV 199

  Fly   202 NLAALLDYCQPGLFPHWRSLDPSQSVRNCTQAMDLAQREFGVPKVLEPEYLASPWLDELSGMTYL 266
            .|:||||||:||||||||:|:.|:|||||.:||:||...||:|||||||||||.|||||||||||
Mosquito   200 LLSALLDYCEPGLFPHWRTLNQSESVRNCERAMNLAYERFGIPKVLEPEYLASRWLDELSGMTYL 264

  Fly   267 SYFMKPGGPGYNATMRWVNTQVKDPVKNFTTDWNDGRVMCEIIKGLGGSAPAPEKLSTDPFHYEN 331
            ||||:||||||||||:|||.|:|.||.|||:|:|||:|.|||||.|||..|.|.|||:||..:|:
Mosquito   265 SYFMRPGGPGYNATMKWVNGQIKRPVTNFTSDFNDGKVFCEIIKDLGGPVPDPHKLSSDPSQWES 329

  Fly   332 NIRKAVDAGARLGVQPILTAKDMANPEVEHLGIMAYAAHLQWVPPRPPLSDLVSVYLESTSGRVG 396
            |.:|.:|.|.:|||:|:|.|||||..:.||||:|||...|:||.|||||:::::|.|||||||||
Mosquito   330 NQQKVIDGGLKLGVKPVLAAKDMATADEEHLGVMAYTTWLRWVVPRPPLANMLTVQLESTSGRVG 394

  Fly   397 EPTHFRIDVMSRDISLSSVRCHVVPPSGQPGQPVRLNAHGEGVFVPERYGMHEIVVEIGEDSLGG 461
            |||.||::.:|||:.:|.||.:|..|:....|.|||.|.|||.|||::|||||||:||.::.|||
Mosquito   395 EPTEFRVEALSRDVDMSRVRAYVGMPNTNTLQQVRLGARGEGTFVPDKYGMHEIVLEIDDNQLGG 459

  Fly   462 HFFRALPRLLQVAPPGMAPCALGSLVEVLVNATGAPKTEDILVTAVSPTGISHNCPLKKIDEGHS 526
            ||||.||||:.||||||||||||||||||||||||||||||||||.||:|....||||||:||||
Mosquito   460 HFFRVLPRLVHVAPPGMAPCALGSLVEVLVNATGAPKTEDILVTAYSPSGRPLKCPLKKIEEGHS 524

  Fly   527 AIFKPDEAGIWEIAITYQGRHIQGGPFTCAVFDASGVSVHGLDGAMPLRAHTFEVDARGVGVSGE 591
            |||||||||:|||||||||||||||||||||||.|||||||||||||||||:||||||||||:||
Mosquito   525 AIFKPDEAGVWEIAITYQGRHIQGGPFTCAVFDPSGVSVHGLDGAMPLRAHSFEVDARGVGVAGE 589

  Fly   592 LHVDIVHDKHSLVCSVEKIVENKYRVTFMPRQNGKYRVYIYFNGYDVKGSPFIMRVGTKGRSGKT 656
            |||||||:|.|||||||::.||||:||||||.|||:|||:||||||||||||||:||:|||||||
Mosquito   590 LHVDIVHEKRSLVCSVERLQENKYQVTFMPRSNGKHRVYVYFNGYDVKGSPFIMKVGSKGRSGKT 654

  Fly   657 RSSP-LHDSKHRSESPSMHFVSTTNTRHNDYRNSSLSRH----NTAERTNSYSPQYSPKLDTTDY 716
            |:|| .||.|.||||||.||.:::.||..|.::.||.|.    .|.:::.|.|||        ||
Mosquito   655 RTSPHQHDGKLRSESPSYHFNASSLTRKADTQSGSLRREIYSPPTVQQSGSRSPQ--------DY 711

  Fly   717 HSSSSRYYKRESEENHATPPPAPPPASGSPTVKYLNSADLYTETLNGRRDSKTSNSSSTKNDYY- 780
            ....  |.|..|:|.:.:  ....||..||:.|.|..|                    |:.||.
Mosquito   712 EPGG--YIKSTSKETYTS--RVMSPARHSPSPKLLFPA--------------------TETDYSG 752

  Fly   781 -YDKENELYSQRRAVTKPKLTPPR--------EERELTSTTNTSSSSSFQQ--RHQQLATSTLTR 834
             :.:..||.||||...:.|.:|.|        :|          ::||:.:  |.:...|.|:..
Mosquito   753 GFRRSTELLSQRRDSDELKTSPVRLGGGGGVVDE----------AASSYVKTIRTENHTTKTIRT 807

  Fly   835 SLSPIPSPTLNTRSSEVHTHSPLTIKTSNQYESSTRN----ITSSPRHASVSPVQRYSPNSAYIT 895
            .|....||..:.|:|. ...||.|:.::...::.|.:    ||::....|.:   ||.|:    .
Mosquito   808 VLDGESSPIAHIRASP-GLKSPQTVVSATLLDTRTASPKPLITTTSTSTSST---RYIPS----P 864

  Fly   896 TATHRMGSPLTSPVSKNGYESSRTVEKSSTYKSTSNYVTDSNIRASPSLYGTAERLRR----TGS 956
            ....|:.||:......||  :.:..|::||||||   ||...:|.||:|    ||:.|    |.:
Mosquito   865 VTEQRVASPIAMHEKSNG--TYKVTERNSTYKST---VTRDVVRDSPTL----ERVVRSPLTTAA 920

  Fly   957 PEPRIDHSSNVRVSSMKPASARRDSWDVINKTKHMLSHNSLESLANMTEKQLNTELQYNRPDLDH 1021
            ....:|:|||::|:......:||||:||||||||:.|.||||||||:||:||||:|.|:|..||:
Mosquito   921 GTSVVDYSSNIKVNGANGQPSRRDSYDVINKTKHLFSQNSLESLANLTERQLNTDLTYDRSTLDN 985

  Fly  1022 ETHRNTQYNKFALHKQQQQQSDYRRDSPDDGERYKPSAITVKSHSNNTYTDKSGGYTKTVKESSE 1086
            :|.:||.:|||:|..:.|.    ||...:|...|                 ::|||.|..:
Mosquito   986 QTEKNTHFNKFSLGTETQP----RRPVIEDEGLY-----------------RAGGYLKNYR---- 1025

  Fly  1087 HVVTESNGHGPSPGYGYSSLSRFRPIDGNATGARAIRVQDIPNGSIGRPVEFEIDGSRAGSGNLE 1151
               ||||.......|.......|.||..:.:|||||||||||:|.:|||||||||||:|||||||
Mosquito  1026 ---TESNESRYESKYSSQLKGGFEPIGRDVSGARAIRVQDIPDGVLGRPVEFEIDGSQAGSGNLE 1087

  Fly  1152 ILVNGGRVTSSVRSLGGQRFIASFTPHEHGTHTVQITFNGETVPGSPWHAEIMSSPGLTALGEST 1216
            ||||||||||:||:||.|||||||||||.||||||||||.||||||||:..||||||||||||||
Mosquito  1088 ILVNGGRVTSAVRALGNQRFIASFTPHESGTHTVQITFNEETVPGSPWNINIMSSPGLTALGEST 1152

  Fly  1217 RLVPANTPAVFEILPPPGQSLSKGECVATVLTPSKSKLNARVTHEAANGAARIEFVPTEVGTHVI 1281
            ||||||.|||||:|||||.|:...:||||||:|||:|::||||||:|||:.||||||:|||||:|
Mosquito  1153 RLVPANLPAVFEVLPPPGASIRGSDCVATVLSPSKTKVSARVTHESANGSLRIEFVPSEVGTHII 1217

  Fly  1282 DASINGTKIAGGPLIAKVYDSSLIQVTEVNGGVVGQACQFRVDASAAGEGQLEISINEGEVPNHV 1346
            :|||.||.:.|||||||||||||||||:||||||||.||||||||||||||||||||||||||||
Mosquito  1218 EASIGGTTLVGGPLIAKVYDSSLIQVTDVNGGVVGQPCQFRVDASAAGEGQLEISINEGEVPNHV 1282

  Fly  1347 QVVGGGRCLVSFTPEQAKSHLIDIKFNGETVRGCPFVCAVADTSRVLLNLSNLELIPVNRPSSFH 1411
            ||||||||||||||||||.||||||||||||.||||||:|||||||||||:||||||||||:|||
Mosquito  1283 QVVGGGRCLVSFTPEQAKPHLIDIKFNGETVIGCPFVCSVADTSRVLLNLTNLELIPVNRPASFH 1347

  Fly  1412 ITVSGGGAAELAVSVRGPQGELPVRVTGDIHAGFTAEFTPTTVGGHSINVEYNGFAVQGTPFLAK 1476
            ||||||||||||||||||||||||||||||||||||||||..||.|:|||||||:.||||||:||
Mosquito  1348 ITVSGGGAAELAVSVRGPQGELPVRVTGDIHAGFTAEFTPNHVGAHTINVEYNGYPVQGTPFVAK 1412

  Fly  1477 SYDASKVVVGSVSRGTMGRPVQFTVDAGDAGEGNLEITISAKGQNIPTQVHPQGSARFSVSFVPT 1541
            ||||:||.|||||:||:||||||||||||||||||||||||||.||||||||||:|:|:|||||.
Mosquito  1413 SYDATKVAVGSVSKGTVGRPVQFTVDAGDAGEGNLEITISAKGHNIPTQVHPQGNAKFAVSFVPA 1477

  Fly  1542 ESCEHTINVSFNKMPVPGCPITVSISGGVAGPQVSLGGPGPVHQTNSFVINHNGGRLEDIEVNVE 1606
            |.|||.||||||||.||||||||.|:||..|||||||||||:|..||.||||.||||||||||||
Mosquito  1478 EPCEHIINVSFNKMLVPGCPITVIINGGTTGPQVSLGGPGPLHMPNSLVINHAGGRLEDIEVNVE 1542

  Fly  1607 GPAGQSVPAQVHQSADGVFKAEFVPRVVGEHRVNVTVNGLPTAGSPYAAKVYDVSAIKVKNVSSG 1671
            ||:|.||||||.|:|||||||||||||||||.|:|||.|.||.||||:||||||:|||||||::|
Mosquito  1543 GPSGHSVPAQVLQTADGVFKAEFVPRVVGEHWVSVTVEGQPTVGSPYSAKVYDVTAIKVKNVNNG 1607

  Fly  1672 TVGKAVTFLVETSQAGPGNLEVTVNGGRVPTSAQAQGQHTYAISFTPREAESHTVELRFNSQDVP 1736
            ||||.|.|||||||||||||||||||||||||||||||||||||||||||::||||||||.||||
Mosquito  1608 TVGKPVVFLVETSQAGPGNLEVTVNGGRVPTSAQAQGQHTYAISFTPREAQNHTVELRFNGQDVP 1672

  Fly  1737 GSPFTCRVAAAARIQSPETMDKVSVGRLFEFVVESDTKPTVEVLGPARRSVPVKIDALGSSTLGY 1801
            ||||||:|:.||||.|.:..||||||..|:||||||..|.|||||||||.|...|....|.:.||
Mosquito  1673 GSPFTCKVSPAARIVSSDLTDKVSVGHTFDFVVESDIAPVVEVLGPARRPVRADIVPAASPSSGY 1737

  Fly  1802 NVKFEPMEVGDHSVEVRLPGGGHVEGSPFLLKAYSAEKVIVTDIRAGVVNKSVSFGINASQAGAG 1866
            .|||||:|||||||||||||.||||||||||||||||||:|||||.|||.|||||||||||||||
Mosquito  1738 RVKFEPVEVGDHSVEVRLPGSGHVEGSPFLLKAYSAEKVVVTDIRPGVVGKSVSFGINASQAGAG 1802

  Fly  1867 NLEIIVAVNGKNVPNFVQSEGNARFKVNFKPTEAATHSLSVRFNGHPVPGSPFSCHIAAAAASPS 1931
            ||||||||.||||||||||||||||||||||||||||||||||||:|||||||:||:..|..|
Mosquito  1803 NLEIIVAVGGKNVPNFVQSEGNARFKVNFKPTEAATHSLSVRFNGYPVPGSPFACHVTHAPVS-- 1865

  Fly  1932 MGLPRAMAMGECLKQAAVKMDNTFELEGFDGVEPQIFVTSPSGDNEHCQLSQHDGGSYSASFRPT 1996
              |.:|:|.||||:||.||.::.||||||||::||:.:|:||||....::|..| ..:..:|.||
Mosquito  1866 --LSKAIATGECLRQAPVKAESVFELEGFDGIDPQVLITAPSGDTVTSRVSFRD-EVHLVAFVPT 1927

  Fly  1997 TVGRHLISVTANDQHINGSPFSCNVFDVSRVSISGLEQQYGPANLGVPVTFSVDAAGAGEGTLEL 2061
            :|||||||||||||||||||||||||||||||||||:.:...|:||||:||||||||||||||||
Mosquito  1928 SVGRHLISVTANDQHINGSPFSCNVFDVSRVSISGLDPRSTMASLGVPLTFSVDAAGAGEGTLEL 1992

  Fly  2062 VVSTDSSTVKAEVVACARGLYDVTFVPQSTEPHYVNITFNEVAVDGSPFRVDIQQHTQHIQIGSL 2126
            ||||.:|||||||.|||||||||||:|||.|||:||||||::.|:|||||.::||:|||:|:|:.
Mosquito  1993 VVSTATSTVKAEVTACARGLYDVTFIPQSCEPHFVNITFNDLPVEGSPFRCEVQQNTQHVQVGNT 2057

  Fly  2127 AAIDFPADDQIVEIFSPDQKSVPYSINRQTAEFRTHMTGNYTLRFIDRETRQHIGSRTLCVFDPT 2191
            ..||..||||.||||.|:.|.||::::|:.||||....|.|.:|:||:|||..|.:||:.||||:
Mosquito  2058 TLIDLMADDQTVEIFDPENKLVPFTLSRKAAEFRAAKIGQYVVRYIDQETRNFIAARTINVFDPS 2122

  Fly  2192 LVKITEVSEAFCHRPASIGVSLNEAGQGDLSALVRCGATEVPHTIRGPSKTGVYEIVYQPTRVAP 2256
            :|||.||.||:||:|||:.||.||||||.|:::||||..||||:|||.:..||:||||.||||||
Mosquito  2123 MVKIVEVGEAYCHKPASLVVSTNEAGQGTLTSMVRCGGLEVPHSIRGTANGGVWEIVYHPTRVAP 2187

  Fly  2257 HKISILFNEVPISLKPLEINVLPASAGKEISVSGLGLYQSRVGKTTSFAIDTVKRPAREFDVVVS 2321
            |||.||:|:||||.|.:|||||..:..|||:|:||||||:|||||||||||||..||||||||||
Mosquito  2188 HKIMILYNQVPISNKAIEINVLAPAMSKEITVNGLGLYQARVGKTTSFAIDTVGHPAREFDVVVS 2252

  Fly  2322 GPGGQALPVRCYQTKNGHLQAEFTINKPGQCVIEVLHQSKPLPGSPFTCESFDSSKVSTQGVTKE 2386
            |||||||||||||||.||||||||:.|.|||:|:||||||||.|||:||||:|.:|:..|.|.|.
Mosquito  2253 GPGGQALPVRCYQTKGGHLQAEFTVQKVGQCLIDVLHQSKPLMGSPYTCESYDPTKIQLQKVPKM 2317

  Fly  2387 PLALHSPNSFTVRTDNAGTAELEAFAISPSNQSIPVLISEQSDGVYNVEFVPSQPGNYKLTLMYG 2451
            .|..:||.|:.|::::||.||:|...:||:.|::||.:::|.|..:::||||...|:||.|:|||
Mosquito  2318 NLCANSPISWIVQSESAGVAEIEVTVLSPTGQNVPVKLTQQDDYEHSIEFVPQAAGHYKATVMYG 2382

  Fly  2452 GETIPSSPLNFTASSSGVRNDARAAGHGLEVCHRNKEASFVVYCPIAPNVQIERLDEYGERIEPK 2516
            ||.:|:||:.|...|:|.::|:.|:|:||||.||.||.||||:||.||||||||.||..|||||:
Mosquito  2383 GEAVPNSPITFAVQSAGGKSDSHASGNGLEVAHRGKETSFVVFCPTAPNVQIERTDEQAERIEPR 2447

  Fly  2517 IKALGNNEWRISYTILSVGKYEIRASCPNRGSLPGSPWHISCVESNKVTPVGGWGTLVDHDGRLI 2581
            ||.:|||:|:|.||||:||:|||||||.|||.||||||:|:|::..||||:||||:.:|..|:|:
Mosquito  2448 IKNMGNNQWKIFYTILTVGRYEIRASCTNRGPLPGSPWNIACLDPAKVTPIGGWGSCLDSSGKLV 2512

  Fly  2582 LPARIIFDVENAGPGKLVCSIDGIEIPVDKLVDGKMCLNITGENLAAGEHDLDLTWSGLTITQCP 2646
            ||::|:||...||||:|.|.:|..|:.|:|...||..|.::.:.||.|||..|||||||.|:|.|
Mosquito  2513 LPSKIVFDTSMAGPGELTCYVDDAEVMVEKQGSGKCVLFLSDDGLAKGEHSFDLTWSGLPISQSP 2577

  Fly  2647 RSAFVTGQQ-AADKVQLMGRGLAAAQAGEAAHFTIDASNAPAGRPEVILTSQDNTSLPVSLAQPR 2710
            ...:|||.. .:|:|.|.||||..||.||.:||||||::|.:|:|||.:...|...|||:|.|||
Mosquito  2578 GFVYVTGMTIGSDRVVLTGRGLTTAQVGEVSHFTIDATDALSGKPEVHMAYDDGEPLPVTLLQPR 2642

  Fly  2711 PSENIWLASYTPLKSTTGTLNLSVKWNGRLVKGCPLTVAVGSSMDASKVIVSGEGLRHGIVGKDI 2775
            |:|.||||||.|.|||.|.|:|.|:||||::||||||:.||.::||:||:.||||||:|:||::|
Mosquito  2643 PNELIWLASYNPHKSTGGPLSLEVEWNGRIIKGCPLTIPVGPAVDAAKVLCSGEGLRNGVVGREI 2707

  Fly  2776 KSWIDTRRAGPGELTAHCAGVRKVAYCELYDHGDATFTLNIKPQESGRHILTIKYGGQNVPGSPF 2840
            ||||||||||||||||||||.|||||||||||||||||||:||||.|||.||||||||:|||||:
Mosquito  2708 KSWIDTRRAGPGELTAHCAGPRKVAYCELYDHGDATFTLNVKPQEPGRHTLTIKYGGQHVPGSPY 2772

  Fly  2841 ALKVAGAPDASKVRVYGPGIEHGVLATFQSRFICDTRGAGAGQLTVRVRGPKGAFRVEMQRESQK 2905
            .|:|.||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||
Mosquito  2773 TLRVVGAPDASKVRVYGPGIEHGVLATFQSRFIVDTRGAGAGQLTVRVRGPKGAFRVEMQRESQK 2837

  Fly  2906 DRTILCKYDPTEPGDYRVEVKWAGEFVPGSPFPVMIFDTEEELRRYLQG 2954
            |||||||||||||||||||||||||.||||||||:||||:|||:|:|.|
Mosquito  2838 DRTILCKYDPTEPGDYRVEVKWAGELVPGSPFPVLIFDTQEELKRFLHG 2886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jbug	NP_001261140.1	CH_jitterbug-like_rpt1	57..166	CDD:409076	90/108 (83%)
		CH_jitterbug-like_rpt2	170..274	CDD:409078	84/103 (82%)
		CH_jitterbug-like_rpt3	275..373	CDD:409034	60/97 (62%)
		IG_FLMN	468..560	CDD:214720	81/91 (89%)
		IG_FLMN	560..648	CDD:214720	74/87 (85%)
		IG_FLMN	1119..1198	CDD:214720	69/78 (88%)
		IG_FLMN	1220..1302	CDD:214720	59/81 (73%)
		IG_FLMN	1310..1389	CDD:214720	74/78 (95%)
		IG_FLMN	1399..1480	CDD:214720	72/80 (90%)
		IG_FLMN	1480..1569	CDD:214720	74/88 (84%)
		IG_FLMN	1575..1659	CDD:214720	68/83 (82%)
		IG_FLMN	1661..1747	CDD:214720	75/85 (88%)
		IG_FLMN	1757..1837	CDD:214720	59/79 (75%)
		IG_FLMN	1837..1926	CDD:214720	80/88 (91%)
		IG_FLMN	1936..2023	CDD:214720	54/86 (63%)
		Filamin	2021..2111	CDD:395505	71/89 (80%)
		IG_FLMN	2198..2280	CDD:214720	56/81 (69%)
		IG_FLMN	2285..2375	CDD:214720	75/89 (84%)
		IG_FLMN	2376..2465	CDD:214720	38/88 (43%)
		Filamin	2474..2555	CDD:395505	59/80 (74%)
		IG_FLMN	2657..2751	CDD:214720	56/93 (60%)
		IG_FLMN	2756..2847	CDD:214720	74/90 (82%)
		IG_FLMN	2850..2944	CDD:214720	90/93 (97%)
jbug	XP_061504219.1	None