Protein Alignment Pten and TEP1

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_014271.3
• Gene: TEP1 / 855595
• SGDID: S000005072
• Length: 434
• Species: Saccharomyces cerevisiae
• Alignment Length: 420
• Identity: 90/420 - (21%)
• Similarity: 158/420 - (37%)
• Gaps: 123/420 - (29%)

  Fly     5 ISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENH 69
            ::||..::...:.|.:   .:.|..||::||..|:|...||.....:.|:||.|:|:...|...|
Yeast    20 VNLMKKILSLPMKKTK---NDIGLRLDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYH 81

  Fly    70 AQ-HYKIYNLCSE--------------------RSYDVAKFR------GRVAVYPFD-------- 99
            .: :::|:|...|                    :.:::.:.|      |::.:.|.|
Yeast    82 GKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESKDFEIQELRSTLINDGKIPISPIDLETRTLVE 146

  Fly   100 --------------DHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFS 150
                          ||.||..||::.....::.:|....:.|..:||:.||||:|.:..|||: .
Yeast   147 EETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLM-K 210

  Fly   151 GIKKSADEALAWYDEKRTK--DRKGVTIPSQRRYVQYFSKLVC-----------SSVPYSKVSLN 202
            .::....||...:.:.|.|  ...|||||||.||::|....:.           .:|.: |....
Yeast   211 YLQCPLGEARLIFMQARFKYGMTNGVTIPSQLRYLRYHEFFITHEKAAQEGISNEAVKF-KFKFR 274

  Fly   203 VCEIRF--------SESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDF-------QKSFV 252
            :.::.|        |||:.|        :..:.|.:...||...| |.:..|.       ..:|:
Yeast   275 LAKMTFLRPSSLITSESAIV--------TTKIQHYNDDRNALLTR-KVVYSDIMAHECGGNMTFI 330

  Fly   253 LTIKPSIPVSGDVKFELT-----KKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEI 312
            .. :..:.:..|.:.|.|     .|:...||           :::.|.| ..:|.|:.||.....
Yeast   331 FG-RDYLTLENDCRIEFTLGTSKSKAASSII-----------SWTSCAS-CWLNIYLETLMHIIK 382

  Fly   313 DDVHKDSEHKRFSEEFKISIVFEAENFSND 342
            ||...|              .|:.|....|
Yeast   383 DDSSPD--------------YFQVERLKRD 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	31/157 (20%)
		PTEN_C2	196..335	CDD:287393	28/158 (18%)
TEP1	NP_014271.3	PTP_PTEN-like	43..251	CDD:350347	53/208 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346246
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001369
OrthoInspector	1	1.000	-	-		oto99650
orthoMCL	1	0.900	-	-		OOG6_100936
Panther	1	1.100	-	-	O	PTHR12305
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1027
SonicParanoid	1	1.000	-	-		X965
TreeFam	0	0.000	Not matched by this tool.
	10	9.770