Protein Alignment Pten and PTEN1

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_198756.2
• Gene: PTEN1 / 833936
• AraportID: AT5G39400
• Length: 412
• Species: Arabidopsis thaliana
• Alignment Length: 339
• Identity: 116/339 - (34%)
• Similarity: 174/339 - (51%)
• Gaps: 63/339 - (18%)

  Fly     9 SNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHY 73
            ::.:||:|||||.|....|||||::||:|.::||.:|| :::..::||.|..|..:|:..|..||
plant    30 NSYLRNLVSKKRRRLIIGGYDLDMSYISDKLLAMSFPA-ERMRAVYRNPLWQVKSVLDMRHPDHY 93

  Fly    74 KIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGR 138
            |:||||.|.|||...|.|||..:||||::.|::::||.||..|..||..|..|:..|||.|||||
plant    94 KVYNLCIEESYDPDNFYGRVERFPFDDNHVPSLKMIQLFCESVHSWLSLDPKNIAVVHCMAGKGR 158

  Fly   139 TGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSS---VPYSKV- 199
            ||.|:.||||:.|:  ||:|||..|..:||.:..||:||||||||:|:|.|:..|   .|..|:
plant   159 TGLMVSAYLVYGGM--SAEEALEMYASRRTTNNNGVSIPSQRRYVKYWSDLLSFSKKGPPEVKLP 221

  Fly   200 ---SLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKP--DRLKTLPIDFQKSFVLTIKP-- 257
               |..:..||..:::.|.::..|   :|.|.:...|..:|  :..:.....|:|.:..:..|
plant   222 QEHSRELLRIRLYDTANVDSVFFV---VSELQEVPNEMYRPSVELARGCCRQFKKGYCRSSSPRY 283

  Fly   258 ----------------------------------------------SIPVSGDVKFELTKKSPDK 276
                                                          .:.||||::....:|....
plant   284 YISHVNCDSEEDEEVTDGEEPHLVVQMDTESSIIDEKTCLDFYFDKPVRVSGDIRITFYQKMIGS 348

  Fly   277 IICHFWLNTFFVRN 290
            .:.:...||.|:.|
plant   349 RLFYTCFNTAFITN 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	55/108 (51%)
		PTEN_C2	196..335	CDD:287393	22/149 (15%)
PTEN1	NP_198756.2	PTP_PTEN	52..207	CDD:350359	79/157 (50%)
		PTEN_C2	<327..395	CDD:371036	9/36 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2643
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001369
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100936
Panther	1	1.100	-	-	O	PTHR12305
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.770