DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pten and AT3G09100

DIOPT Version :9

Sequence 1:	NP_001162933.1	Gene:	Pten / 43991	FlyBaseID:	FBgn0026379	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	NP_974263.1	Gene:	AT3G09100 / 820064	AraportID:	AT3G09100	Length:	672	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	110/574 - (19%)
Similarity:	203/574 - (35%)	Gaps:	162/574 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RNVVSKKRIRYKEKGYDLDLT----YINDNIIAMGYPAPD-KLEGLFRNRLEDVFKLLEENHAQH 72
            :.|:..:||..::.|..:|||    |         |...| |.||:                 :|
plant   124 KQVIHNQRIAGRKLGLVIDLTNTTRY---------YSTTDLKKEGI-----------------KH 162

  Fly    73 YKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWL--KEDSSNVVAVHCKAG 135
            .||  .|          :||.||       |..:. :..|.::|:.::  .:.|...:.|||..|
plant   163 VKI--AC----------KGRDAV-------PDNVS-VNAFVNEVNQFVLNLKHSKKYILVHCTHG 207

  Fly   136 KGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYF------SKLVCSSV 194
            ..|||.||..||:.|| ..:..:||..:.:.|.   .|:..|.....:..|      ..::|.|.
plant   208 HNRTGFMIVHYLMRSG-PMNVTQALKIFSDARP---PGIYKPDYIDALYSFYHEIKPESVICPST 268

  Fly   195 P----YSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRL-KTLPID----FQKS 250
            |    .:::.||...:...|.......|.|:......|....:.:..|.| ..:|.|    :::.
plant   269 PEWKRSTELDLNGEALPDDEDDDGGPAGPVQGFQEESHQVDVKMSNDDVLGDEIPPDQEEGYRQF 333

  Fly   251 FVLTIKPSIPVSGDVKF------ELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSK 309
            |...:..:|...|..:|      .|.:::...:...::        |:..::|||  :|:..|:.
plant   334 FYRMLSLNIGGRGCSQFPGSHPVSLNRENLQLLRQRYY--------YATWKADGT--RYMMLLTT 388

  Fly   310 SEIDDVHKDSEHKRFSEEFKI-----SIVFEAENFS-------NDVQAEASEKERNENVLNFERS 362
            .....|.:....:|....|..     .|..:..:|:       .|...:..::||...:
plant   389 DGCYIVDRSFRFRRVQMRFPFRHPTEGISDKVHHFTLLDGEMIIDTLPDKQKQERRYLI------ 447

  Fly   363 DYDSLSPN--------CYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKI-QYDTSTNSKNTSTA 418
             ||.::.|        .|...|:|         :.:.|:..:|:...:.| :||..      ...
plant   448 -YDMVAINGQSVVERPFYERWKML---------EKEVIDPRNHEKARSHIYRYDLE------PFR 496

  Fly   419 CKRK--------QPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKT--DLIKWQNSEVHITSDTRS 473
            .:||        :...|..:|||:......|.:.  ::.|.:.:|  .|:||:..|::.......
plant   497 VRRKDFWLLSAVEKVLKGFIPSLSHEADGLIFQG--WDDPYVPRTHEGLLKWKYPEMNSVDFLYE 559

  Fly   474 INEN-------------KNINYNSYITCKQSSPK------FNCGTEDGEEDWES 508
            .:|:             |:::.||.:....|.|.      ..|..:..|:.|.|
plant   560 QDESGRGMLSLFERGKKKHMDGNSVVFRDDSDPAEYSGKIVECSWDQDEKVWVS 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	27/110 (25%)
Pten	NP_001162933.1	PTEN_C2	196..335	CDD:287393	25/154 (16%)
AT3G09100	NP_974263.1	RNA_5'-triphosphatase	86..252	CDD:350352	43/177 (24%)
		mRNA_cap_enzyme	354..547	CDD:396068	37/226 (16%)
		mRNA_cap_C	552..645	CDD:397827	10/62 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910