Protein Alignment Pten and dnajc6

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_021332834.1
• Gene: dnajc6 / 796345
• ZFINID: ZDB-GENE-080104-2
• Length: 979
• Species: Danio rerio
• Alignment Length: 494
• Identity: 123/494 - (24%)
• Similarity: 204/494 - (41%)
• Gaps: 94/494 - (19%)

  Fly     1 MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLL 65
            :.:||...|..:.|.|:.     ..|| :||:.||...||.|.||| :.:|..:||..||:...|
Zfish   100 LKDTIKDTSTKVMNQVAT-----YTKG-ELDIAYITSRIIVMSYPA-ETVEMGYRNHTEDIRSFL 157

  Fly    66 EENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAV 130
            :..||.||.::|| |:|:|..|||..||:...:.....|::..:...|.::..|||::..||..:
Zfish   158 DSRHADHYTVFNL-SQRNYRGAKFSNRVSECNWPSRQAPSLHNLFAVCKNMYNWLKQNPKNVCVI 221

  Fly   131 HCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCS--S 193
            .|..|:..:|.::||...|..:..:...|:.....||  ...|:. ||.|||:.|...||..  :
Zfish   222 TCSDGRAPSGVLVCAMFCFCHLFANPVPAMQLLSAKR--PGSGLW-PSHRRYIGYVCSLVSEKPT 283

  Fly   194 VPYSKVSLNVCEIRFSESSCV--QNLGMVE-CSISVLHDSATENAKP-DRLKTLPIDFQKSFVLT 254
            ||:|| .|.:..:..|...|.  |..|... |.:.:........|:. :|::...|...|   :.
Zfish   284 VPHSK-PLVIKTVTISPVPCFNKQRSGCRPFCDVLIGETKIFSTAQEYERMREHRIQEGK---VV 344

  Fly   255 IKPSIPVSGDV--------KFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSE 311
            ....:...|||        ...|..|..:..|.....:|.|:...|      ||.|::    |:|
Zfish   345 FPVGVSAQGDVVISVYHMRSHALQAKVTNTQIFQIQFHTGFIAPGS------TVLKFM----KTE 399

  Fly   312 IDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPN----CY 372
            :|..  ||..| :.:.|.:.|         |::.|::||:: :....:|:.....||||    |:
Zfish   400 LDAC--DSPEK-YPQLFHVLI---------DIEVESTEKQK-DLTPPWEQFPTKDLSPNVLFSCH 451

  Fly   373 AEKKVLTAIVND------------------NTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTAC 419
            .|.:...||.::                  ....::..|..|.:.:....|...::|.|  |.|.
Zfish   452 QEHQDALAIADEMEGLDLEDPAQGHSSCGGRVGPNEESEPSDDEMLSLSSQQSNASNEK--SKAA 514

  Fly   420 KRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLI 458
            ||.:|.:....|                  |:.::.||:
Zfish   515 KRPEPQAAAPPP------------------PAAEEVDLL 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	52/157 (33%)
		PTEN_C2	196..335	CDD:463081	32/150 (21%)
dnajc6	XP_021332834.1	PTP_auxilin_N	115..277	CDD:350411	56/172 (33%)
		PTEN_C2	285..420	CDD:463081	34/160 (21%)
		PHA03247	<538..842	CDD:223021
		DnaJ	<927..968	CDD:99751