Protein Alignment Pten and Tns3

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_011242029.1
• Gene: Tns3 / 319939
• MGIID: 2443012
• Length: 1553
• Species: Mus musculus
• Alignment Length: 571
• Identity: 134/571 - (23%)
• Similarity: 232/571 - (40%)
• Gaps: 141/571 - (24%)

  Fly    25 EKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKF 89
            |..::|||||:.:.|||:.:||....|. :.:.|::|.::|:..|..:|.:.|| ||:.||:.|.
Mouse   115 EDSHELDLTYVTERIIAVSFPASCSEES-YLHSLQEVTRMLKCKHGDNYLVLNL-SEKRYDLTKL 177

  Fly    90 RGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKK 154
            ..::....:.:.:.|.::.:...|...:.||..|..:||.:||:.||||.|.:|.:|:.|:.:..
Mouse   178 NPKIMDVGWPELHAPPLDKMCTICKAQESWLNNDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSA 242

  Fly   155 SADEALAWYDEKRTKDRK--GVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRF--------- 208
            |||:||..:..|:..|.|  .:..|||:||||:.|.|:..::   |::.:...:.|
Mouse   243 SADQALDRFAMKKFYDDKISALMEPSQKRYVQFLSGLLSGAM---KMNTSPLFLHFVIMHGVPSF 304

  Fly   209 -SESSCVQNLGMVECS----ISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDV--- 265
             :..:|...|.:.:..    .|.:::..:||  |.|::           :.|:|:..:.||:
Mouse   305 DTGGACRPFLKLYQAMQPVYTSGIYNVGSEN--PSRIR-----------IAIEPAQLLKGDIMVK 356

  Fly   266 ----KFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSE 326
                ||   :.:...:|.....:|            |.|..|.....|.|:|...||.   ||.:
Mouse   357 CYHKKF---RSATRDVIFRLQFHT------------GAVQGYGLLFGKEELDSACKDD---RFPD 403

  Fly   327 EFKISIVFEAENFSNDVQAEASEKERNENVLNFERS---DYDSLSP--------NCYAEKKV--- 377
            ..||.:||.|          ..||.:....|..::.   ||::..|        |..|:.:|
Mouse   404 YGKIELVFSA----------TPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMSADGEVLHT 458

  Fly   378 -------LTAIVNDNTTKSQTI----------ETLDHKDIVTKIQYDT--STNSKNTSTACKRKQ 423
                   |.|.|...:.....|          .:.||.|....:..|:  ||.|..|....:|..
Mouse   459 QGPVDGSLYAKVRKKSASDTGIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERLT 523

  Fly   424 PNSKT-LLP-------------SLNDS----------------TKEEIKRN-HIFNQPSIK--KT 455
            |.::. |.|             .|.||                |:..:... |:....::|  :|
Mouse   524 PGARRGLSPQEKAELDQLLSGFGLEDSASSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRET 588

  Fly   456 DLI--KWQNSEVHITSD--TRSINENKNINYNSYITCKQSSPKFNCGTEDG 502
            |::  :..:.::|....  |.|.:|.....:....||.:||.  |....||
Mouse   589 DILDDEMPHHDLHSVDSLGTLSSSEGPQSTHLGPFTCLKSSQ--NSLLSDG 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	34/108 (31%)
		PTEN_C2	196..335	CDD:287393	30/159 (19%)
Tns3	XP_011242029.1	C1	35..81	CDD:237996
		PTP_tensin-3	121..279	CDD:350409	55/159 (35%)
		PTEN_C2	286..412	CDD:371036	29/156 (19%)
		PHA03307	645..>1077	CDD:223039
		PHA03247	<907..1186	CDD:223021
		SH2_Tensin_like	1276..1392	CDD:198181
		PTB_tensin	1416..1547	CDD:269924

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810