Protein Alignment Pten and Tpte

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_954866.2
• Gene: Tpte / 234129
• MGIID: 2446460
• Length: 664
• Species: Mus musculus
• Alignment Length: 365
• Identity: 126/365 - (34%)
• Similarity: 185/365 - (50%)
• Gaps: 69/365 - (18%)

  Fly     8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQH 72
            :..:.|.:||..:.|||:.|:||||||:.:.||||.:|:..: |..:||.:::|.:.|:..|..|
Mouse   335 LERLTRKLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGR-ESFYRNPIKEVVRFLDTKHPNH 398

  Fly    73 YKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKG 137
            |::|||||||:||...|..||.....||||.||:|.:..|..:|:.|:.:|..||||:|||.|||
Mouse   399 YQVYNLCSERAYDPKHFHYRVRRIMIDDHNVPTLEEMLLFSKEVNNWMAQDPENVVAIHCKGGKG 463

  Fly   138 RTGTMICAYLVFSGIKKSADEALAWYDEKRTKDR------KGVTIPSQRRYVQYFSKLVCS---S 193
            |||||:||.|:.|.|..:|.|:|.::.|:|| |:      :|:..|||.|||:||.||..:   :
Mouse   464 RTGTMVCACLIASEIVLNAKESLYFFGERRT-DKSNSSKFQGIETPSQNRYVKYFEKLKINYQLT 527

  Fly   194 VPYSKV--------------------SLNVCEIRFSE---SSCVQNLGMVECSISVLHDSATENA 235
            :|..||                    .|.|..|.:.|   |.|...    .|.|  .||..|:.|
Mouse   528 LPPKKVLVIKRLVVYSIHGVGKGDGSDLEVQIIMWQETVFSFCNSR----NCMI--FHDPETDRA 586

  Fly   236 --KPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDG 298
              .......|..|.:..|   :.|::|           |..|.....||.:|.|::|
Mouse   587 IINVFHCPALYDDVKVKF---LSPNLP-----------KYYDDCPFFFWFHTSFIKN-------- 629

  Fly   299 TVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAEN 338
              |:..  |.::|:|:.||....|.:.|:|.:.:.| .||
Mouse   630 --NRLY--LPRNELDNTHKPKTWKIYGEKFAVEVDF-GEN 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	52/108 (48%)
		PTEN_C2	196..335	CDD:287393	35/163 (21%)
Tpte	NP_954866.2	PTPc_motif	413..>478	CDD:214649	33/64 (52%)
		PTEN_C2	529..663	CDD:287393	37/166 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8442
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001369
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100936
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710